A new view on hypocortisolism

Stress, Adaptation, and Disease: Allostasis and Allostatic Load

1998 • 4,336 citations

A Syndrome produced by Diverse Nocuous Agents

1936 • 3,733 citations

Stress and the Individual

1993 • 3,458 citations

Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions*

1984 • 3,073 citations

Biological basis of the behavior of sick animals

1988 • 2,123 citations

The potential role of hypocortisolism in the pathophysiology of stress-related bodily disorders

2000 • 1,655 citations

Organization of the stress system and its dysregulation in melancholic and atypical depression: high vs low CRH/NE states

2002 • 1,241 citations

When Not Enough Is Too Much: The Role of Insufficient Glucocorticoid Signaling in the Pathophysiology of Stress-Related Disorders

2003 • 1,155 citations

Cytokines for psychologists: Implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition.

1998 • 1,130 citations

The role of adrenocorticoids as modulators of immune function in health and disease: neural, endocrine and immune interactions

1997 • 827 citations

Burnout, Perceived Stress, and Cortisol Responses to Awakening

1999 • 819 citations

Comorbidity of fibromyalgia with medical and psychiatric disorders

1992 • 496 citations

Glucocorticoids promote a TH2 cytokine response by CD4+ T cells in vitro.

1996 • 493 citations

CSF Norepinephrine Concentrations in Posttraumatic Stress Disorder

2001 • 451 citations

Chronic Pain and Fatigue Syndromes: Overlapping Clinical and Neuroendocrine Features and Potential Pathogenic Mechanisms

1997 • 429 citations

Hypocortisolism and increased glucocorticoid sensitivity of pro-Inflammatory cytokine production in Bosnian war refugees with posttraumatic stress disorder

2004 • 388 citations

Chronic widespread pain and fibromyalgia: what we know, and what we need to know

2003 • 383 citations

Posttraumatic Stress Disorder in Female Veterans

2004 • 342 citations

Abuse-Related Posttraumatic Stress Disorder and Alterations of the Hypothalamic-Pituitary-Adrenal Axis in Women With Chronic Pelvic Pain

1998 • 309 citations

The Locus Coeruleus as a Site for Integrating Corticotropin‐Releasing Factor and Noradrenergic Mediation of Stress Responsesa

1993 • 297 citations

Neuroendocrine and Psychophysiologic Responses in PTSD: A Symptom Provocation Study

1999 • 282 citations

Salivary cortisol response to awakening in chronic fatigue syndrome

2004 • 262 citations

Function of the hypothalamic-pituitary-adrenal axis in patients with fibromyalgia and low back pain.

1998 • 261 citations

Fibromyalgia: A Stress Disorder?

2004 • 251 citations

Prevalence and Impact of Posttraumatic Stress Disorder-Like Symptoms on Patients With Fibromyalgia Syndrome

2000 • 242 citations

Responses of the sympathetic nervous system and the hypothalamic–pituitary–adrenal axis to interleukin-6: A pilot study in fibromyalgia

2000 • 230 citations

The relationship between symptoms of post-traumatic stress disorder and pain, affective disturbance and disability among patients with accident and non-accident related pain

1996 • 228 citations

Suppression of Cellular Immunity in Men With a Past History of Posttraumatic Stress Disorder

2001 • 218 citations

Chronic pain syndromes and their relation to childhood abuse and stressful life events

2003 • 212 citations

Prevalence of post-traumatic stress disorder in fibromyalgia patients: Overlapping syndromes or post-traumatic fibromyalgia syndrome?

2002 • 200 citations

Endogenous glucocorticoids restrain catecholamine synthesis and release at rest and during immobilization stress in rats.

1993 • 180 citations

Cytokines and Chronic Fatigue Syndrome

2001 • 167 citations

Relationship of Physical Symptoms to Posttraumatic Stress Disorder Among Veterans Seeking Care for Gulf War-Related Health Concerns

2000 • 152 citations

Endogenous Glucocorticoids Protect Against Cytokine-Mediated Lethality During Viral Infection

1999 • 149 citations

Endocrine Correlates of Stress Vulnerability

1993 • 147 citations

Glucocorticoids and Inflammation Revisited: The State of the Art

2002 • 129 citations

Musculoskeletal manifestations and autoantibody profilein 90 hepatitis C virus infected israeli patients

1998 • 128 citations

Fibromyalgia as a sympathetically maintained pain syndrome

2004 • 120 citations

Corticotropin-releasing factor administered into the locus coeruleus, but not the parabrachial nucleus, stimulates norepinephrine release in the prefrontal cortex

1995 • 109 citations

Multiple Mycoplasmal Infections Detected in Blood of Patients with Chronic Fatigue Syndrome and/or Fibromyalgia Syndrome

1999 • 109 citations

The immune-inflammatory pathophysiology of fibromyalgia: increased serum soluble gp130, the common signal transducer protein of various neurotrophic cytokines

1999 • 101 citations

Posttraumatic Stress Symptomatology Is Associated With Unexplained Illness Attributed to Persian Gulf War Military Service

2001 • 101 citations

Pain and PTSD symptoms in female veterans⋆,⋆⋆

2003 • 101 citations

Comorbidity of Fibromyalgia and Posttraumatic Stress Disorder Symptoms in a Community Sample of Women

2004 • 99 citations

Fibromyalgia-associated hepatitis C virus infection

1997 • 97 citations

Differential Responsivity of the Hypothalamic‐Pituitary‐Adrenal Axis to Glucocorticoid Negative‐Feedback and Corticotropin Releasing Hormone in Rats Undergoing Morphine Withdrawal: Possible Mechanisms Involved in Facilitated and Attenuated Stress Responses

2001 • 91 citations

Cytokine and Other Immunologic Markers in Chronic Fatigue Syndrome and Their Relation to Neuropsychological Factors

2001 • 88 citations

Cortisol and hypothalamic–pituitary–gonadal axis hormones in follicular-phase women with fibromyalgia and chronic fatigue syndrome and effect of depressive symptoms on these hormones

2004 • 86 citations

Normal production of inflammatory cytokines in chronic fatigue and fibromyalgia syndromes determined by intracellular cytokine staining in short-term cultured blood mononuclear cells

2003 • 85 citations

Elevated Cytotoxicity in Combat Veterans with Long-Term Post-traumatic Stress Disorder: Preliminary Observations

1998 • 83 citations

Intermittent Morphine Administration Induces Dependence and is a Chronic Stressor in Rats

2003 • 80 citations

Allostatic Load, Perceived Stress, and Health: A Prospective Study in Two Age Groups

2004 • 75 citations

High prevalence ofMycoplasmainfections among European chronic fatigue syndrome patients. Examination of fourMycoplasmaspecies in blood of chronic fatigue syndrome patients

2002 • 75 citations

Fibromyalgia, hepatitis C infection, and the cytokine connection

2003 • 61 citations

Paradoxical Effects of Chronic Morphine Treatment on the Temperature and Pituitary‐Adrenal Responses to Acute Restraint Stress: A Chronic Stress Paradigm

2001 • 60 citations

Regulation of a putative neurotransmitter effect of corticotropin-releasing factor: effects of adrenalectomy.

1997 • 59 citations

Adrenalectomy augments in vivo release of norepinephrine in the paraventricular nucleus during immobilization stress.

1993 • 52 citations

Regulation of a Putative Neurotransmitter Effect of Corticotropin-Releasing Factor: Effects of Adrenalectomy

1997 • 52 citations

Glucocorticoid-induced sympathoinhibition in humans

1995 • 49 citations

CRH Effects on Central Noradrenergic Neurons: Relationship to Stress

1988 • 35 citations

Atypical depression as a secondary symptom in chronic fatigue syndrome

2003 • 18 citations