DAD1 Is Required for the Function and the Structural Integrity of the Oligosaccharyltransferase Complex

Biological roles of oligosaccharides: all of the theories are correct

1993 • 5,121 citations

Secreted placental alkaline phosphatase: a powerful new quantitative indicator of gene expression in eukaryotic cells

1988 • 687 citations

Signals from the Stressed Endoplasmic Reticulum Induce C/EBP-Homologous Protein (CHOP/GADD153)

1996 • 671 citations

PROTEIN TRANSPORT ACROSS THE EUKARYOTIC ENDOPLASMIC RETICULUM AND BACTERIAL INNER MEMBRANES

1996 • 560 citations

A mammalian homolog of SEC61p and SECYp is associated with ribosomes and nascent polypeptides during translocation

1992 • 450 citations

Oligosaccharyltransferase activity is associated with a protein complex composed of ribophorins I and II and a 48 kd protein

1992 • 291 citations

A signal sequence receptor in the endoplasmic reticulum membrane

1987 • 291 citations

Proteins of rough microsomal membranes related to ribosome binding. I. Identification of ribophorins I and II, membrane proteins characteristics of rough microsomes

1978 • 281 citations

Biochemistry, molecular biology, and genetics of the oligosaccharyltransferase

1996 • 253 citations

The small GTP-binding protein rab6 functions in intra-Golgi transport.

1994 • 251 citations

Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells.

1993 • 223 citations

Binding of ribosomes to the rough endoplasmic reticulum mediated by the Sec61p-complex.

1994 • 191 citations

DAD1, the defender against apoptotic cell death, is a subunit of the mammalian oligosaccharyltransferase

1997 • 177 citations

A tetrameric complex of membrane proteins in the endoplasmic reticulum

1993 • 163 citations

The yeast WBP1 is essential for oligosaccharyl transferase activity in vivo and in vitro.

1992 • 156 citations

Proteins of rough microsomal membranes related to ribosome binding. II. Cross-linking of bound ribosomes to specific membrane proteins exposed at the binding sites

1978 • 142 citations

Yeast Wbp1p and Swp1p form a protein complex essential for oligosaccharyl transferase activity.

1993 • 125 citations

The essential OST2 gene encodes the 16-kD subunit of the yeast oligosaccharyltransferase, a highly conserved protein expressed in diverse eukaryotic organisms.

1995 • 122 citations

Human ribophorins I and II: the primary structure and membrane topology of two highly conserved rough endoplasmic reticulum-specific glycoproteins.

1987 • 106 citations

The Saccharomyces cerevisiae oligosaccharyltransferase is a protein complex composed of Wbp1p, Swp1p, and four additional polypeptides.

1994 • 105 citations

The 48-kDa subunit of the mammalian oligosaccharyltransferase complex is homologous to the essential yeast protein WBP1.

1992 • 88 citations

Antiribophorin antibodies inhibit the targeting to the ER membrane of ribosomes containing nascent secretory polypeptides.

1990 • 83 citations

Biosynthesis and processing of ribophorins in the endoplasmic reticulum.

1984 • 83 citations

Inhibition of N‐linked glycosylation induces early apoptosis in human promyelocytic HL‐60 cells

1995 • 73 citations

An essential 45 kDa yeast transmembrane protein reacts with anti-nuclear pore antibodies: purification of the protein, immunolocalization and cloning of the gene.

1991 • 72 citations

A specific screen for oligosaccharyltransferase mutations identifies the 9kDa OST5 protein required for optimal activity invivo and invitro

1997 • 68 citations

The alpha subunit of the Saccharomyces cerevisiae oligosaccharyltransferase complex is essential for vegetative growth of yeast and is homologous to mammalian ribophorin I.

1995 • 68 citations

The N‐oligosaccharyltransferase complex from yeast

1994 • 68 citations

The highly conserved DAD1 protein involved in apoptosis is required for N‐linked glycosylation

1997 • 59 citations

Isolation and characterization of cDNA clones for rat ribophorin I: complete coding sequence and in vitro synthesis and insertion of the encoded product into endoplasmic reticulum membranes

1987 • 47 citations

Purification and characterization of avian oligosaccharyltransferase. Complete amino acid sequence of the 50-kDa subunit.

1994 • 44 citations

Interactions among Subunits of the Oligosaccharyltransferase Complex

1997 • 41 citations

O-glycosylation of intact and truncated ribophorins in brefeldin A-treated cells: newly synthesized intact ribophorins are only transiently accessible to the relocated glycosyltransferases

1992 • 35 citations

Rat ribophorin II: Molecular cloning and chromosomal localization of a highly conserved transmembrane glycoprotein of the rough endoplasmic reticulum

1991 • 17 citations