Relationship between Productive HIV-1 Infection of Macrophages and CCR5 Utilization
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References (47)
Current protocols in molecular biology
1988 • 7,584 citations
Identification of a major co-receptor for primary isolates of HIV-1
1996 • 3,649 citations
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5
1996 • 3,189 citations
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
1998 • 2,929 citations
CC CKR5: A RANTES, MIP-1α, MIP-1β Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1
1996 • 2,735 citations
The β-Chemokine Receptors CCR3 and CCR5 Facilitate Infection by Primary HIV-1 Isolates
1996 • 2,326 citations
The Role of Mononuclear Phagocytes in HTLV-III/LAV Infection
1986 • 1,828 citations
The antigenic structure of the HIV gp120 envelope glycoprotein
1998 • 1,206 citations
Effects of CCR5 and CD4 Cell Surface Concentrations on Infections by Macrophagetropic Isolates of Human Immunodeficiency Virus Type 1
1998 • 1,202 citations
Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene
1992 • 917 citations
Pathogenesis of human immunodeficiency virus infection
1993 • 835 citations
Dual Infection of the Central Nervous System by AIDS Viruses with Distinct Cellular Tropisms
1987 • 831 citations
A Conserved HIV gp120 Glycoprotein Structure Involved in Chemokine Receptor Binding
1998 • 814 citations
CCR5 Levels and Expression Pattern Correlate with Infectability by Macrophage-tropic HIV-1, In Vitro
1997 • 722 citations
Tyrosine Sulfation of the Amino Terminus of CCR5 Facilitates HIV-1 Entry
1999 • 688 citations
Macrophage-tropic human immunodeficiency virus isolates from different patients exhibit unusual V3 envelope sequence homogeneity in comparison with T-cell-tropic isolates: definition of critical amino acids involved in cell tropism
1992 • 594 citations
The V3 domain of the HIV–1 gp120 envelope glycoprotein is critical for chemokine–mediated blockade of infection
1996 • 499 citations
Length mutations in human mitochondrial DNA: direct sequencing of enzymatically amplified DNA
1987 • 381 citations
Mechanism of Transdominant Inhibition of CCR5-mediated HIV-1 Infection by ccr5Δ32
1997 • 371 citations
Interaction of Chemokine Receptor CCR5 with its Ligands: Multiple Domains for HIV-1 gp120 Binding and a Single Domain for Chemokine Binding
1997 • 363 citations
Fusogenic mechanisms of enveloped-virus glycoproteins analyzed by a novel recombinant vaccinia virus-based assay quantitating cell fusion-dependent reporter gene activation
1994 • 343 citations
Identification of a determinant within the human immunodeficiency virus 1 surface envelope glycoprotein critical for productive infection of primary monocytes.
1991 • 272 citations
CD4, CXCR-4, and CCR-5 dependencies for infections by primary patient and laboratory-adapted isolates of human immunodeficiency virus type 1
1997 • 237 citations
CCR5 Expression Correlates with Susceptibility of Maturing Monocytes to Human Immunodeficiency Virus Type 1 Infection
1998 • 207 citations
Expression of CCR5 Increases during Monocyte Differentiation and Directly Mediates Macrophage Susceptibility to Infection by Human Immunodeficiency Virus Type 1
1998 • 206 citations
HIV-1-induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR-5 co-receptor
1997 • 203 citations
Role of CCR5 in infection of primary macrophages and lymphocytes by macrophage-tropic strains of human immunodeficiency virus: resistance to patient-derived and prototype isolates resulting from the delta ccr5 mutation
1997 • 194 citations
CXCR-4 Is Expressed by Primary Macrophages and Supports CCR5-Independent Infection by Dual-Tropic but Not T-Tropic Isolates of Human Immunodeficiency Virus Type 1
1998 • 185 citations
Human Immunodeficiency Virus Type 1 T-Lymphotropic Strains Enter Macrophages via a CD4- and CXCR4-Mediated Pathway: Replication Is Restricted at a Postentry Level
1998 • 170 citations
Identification and Characterization of the CXCR4 Chemokine Receptor in Human T Cell Lines: Ligand Binding, Biological Activity, and HIV-1 Infectivity
1998 • 167 citations
Macrophage tropism of human immunodeficiency virus type 1 and utilization of the CC-CKR5 coreceptor
1997 • 165 citations
CXCR4 as a Functional Coreceptor for Human Immunodeficiency Virus Type 1 Infection of Primary Macrophages
1998 • 150 citations
Analysis of the Critical Domain in the V3 Loop of Human Immunodeficiency Virus Type 1 gp120 Involved in CCR5 Utilization
1999 • 122 citations
Identification of Envelope V3 Loop as the Major Determinant of CD4 Neutralization Sensitivity of HIV-1
1992 • 117 citations
CXCR4 is a functional coreceptor for infection of human macrophages by CXCR4-dependent primary HIV-1 isolates.
1998 • 112 citations
Cutting Edge: CXCR4 Is a Functional Coreceptor for Infection of Human Macrophages by CXCR4-Dependent Primary HIV-1 Isolates
1998 • 95 citations
Macrophage-tropic HIV: critical for AIDS pathogenesis?
1994 • 88 citations
CC Chemokine Receptor 5-Mediated Signaling and HIV-1 Co-receptor Activity Share Common Structural Determinants
1997 • 79 citations
Multiple Residues Contribute to the Inability of Murine CCR-5 To Function as a Coreceptor for Macrophage-Tropic Human Immunodeficiency Virus Type 1 Isolates
1998 • 69 citations
The Amino Terminus of Human CCR5 Is Required for Its Function as a Receptor for Diverse Human and Simian Immunodeficiency Virus Envelope Glycoproteins
1998 • 63 citations
Role of macrophages in the pathogenesis of human immunodeficiency virus (HIV) infection
1995 • 62 citations
Structure–function studies of the HIV-1 coreceptors
1998 • 61 citations
Role of Naturally Occurring Basic Amino Acid Substitutions in the Human Immunodeficiency Virus Type 1 Subtype E Envelope V3 Loop on Viral Coreceptor Usage and Cell Tropism
1999 • 49 citations
Macrophage-tropic HIV-1 variants: initiators of infection and AIDS pathogenesis?
1994 • 44 citations
The Skin as Target, Vector, and Effector Organ in Human Immunodeficiency Virus Disease
1995 • 23 citations
Adaptation of human immunodeficiency virus type 1 to cells expressing a binding-deficient CD4 mutant (lysine 46 to aspartic acid)
1995 • 15 citations
HIV-1 V3 envelope sequences required for macrophage infection
1995 • 7 citations