Phelorphan, an inhibitor of enzymes involved in the biodegradation of enkephalins, affected the withdrawal symptoms in chronic morphine-dependent rats

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

Endogenous opioid peptides: multiple agonists and receptors

1977 • 2,494 citations

The enkephalinase inhibitor thiorphan shows antinociceptive activity in mice

1980 • 705 citations

Development of physical dependence on morphine in respect to time and dosage and quantification of the precipitated withdrawal syndrome in rats

1973 • 523 citations

Biological inactivation of enkephalins and the role of enkephalin-dipeptidyl-carboxypeptidase (“enkephalinase”) as neuropeptidase

1981 • 382 citations

Central and peripheral actions of morphine on intestinal transit.

1978 • 168 citations

Circulating opioids: Possible physiological roles in central nervous function

1982 • 92 citations

Suppression of withdrawal symptoms by dynorphin in heroin addicts

1982 • 92 citations

Differential epileptogenic potentials of selective? and? opiate receptor agonists

1983 • 56 citations

Tolerance and dependence induced by morphine-like pituitary peptides in rats

1976 • 55 citations

Opioid peptides inhibit intestinal transit in the rat by a central mechanism

1982 • 46 citations

Sexual Aspects of Drug Abuse in Narcotic Addicts*

1976 • 31 citations

Inhibition of enkephalinase activity attenuates naloxone-precipitated withdrawal symptoms

1987 • 26 citations

Peptidase inhibitors reduce opiate narcotic withdrawal signs, including seizure activity, in the rat

1982 • 23 citations

Enkephalinase inhibition suppresses naloxone-induced jumping in morphine-dependent mice.

1986 • 18 citations

Physical dependence produced by chronic intracerebroventricular infusion of [D-Arg]kyotorphin or thiorphan to rats

1984 • 12 citations

Opioid tolerance and dependence in light of the multiplicity of opioid receptors.

1984 • 9 citations

Effect of various enkephalin analogs and dipeptides on the enzymatic activity of enkephalinase B isolated from calf-brain striatum

1986 • 6 citations

Local connectedness and other properties of GA compactifications

1972 • 4 citations