Epstein–Barr virus latent-infection membrane proteins are palmitoylated and raft-associated: Protein 1 binds to the cytoskeleton through TNF receptor cytoplasmic factors

Functional rafts in cell membranes

1997 • 9,471 citations

Regulation of Renal Organic Anion Transporter 3 (SLC22A8) Expression and Function by the Integrity of Lipid Raft Domains and their Associated Cytoskeleton

2013 • 2,950 citations

FUNCTIONS OF LIPID RAFTS IN BIOLOGICAL MEMBRANES

1998 • 2,942 citations

Structure and Function of Sphingolipid- and Cholesterol-rich Membrane Rafts

2000 • 2,321 citations

An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells

1985 • 1,257 citations

The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family

1995 • 990 citations

LAT Palmitoylation

1998 • 837 citations

Epstein-Barr virus latent membrane protein 1 is essential for B-lymphocyte growth transformation.

1993 • 778 citations

Interaction of influenza virus haemagglutinin with sphingolipid-cholesterol membrane domains via its transmembrane domain

1997 • 644 citations

Role of Lipid Modifications in Targeting Proteins to Detergent-resistant Membrane Rafts

1999 • 626 citations

Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23

1990 • 585 citations

Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr Virus LMP1 Domain Important for B-Lymphocyte Transformation: Role in NF-κB Activation

1996 • 491 citations

The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor kappa B.

1992 • 416 citations

Epstein-Barr virus latent infection membrane protein alters the human B-lymphocyte phenotype: deletion of the amino terminus abolishes activity

1988 • 403 citations

The Epstein–Barr virus oncogene product latent membrane protein 1 engages the tumor necrosis factor receptor-associated death domain protein to mediate B lymphocyte growth transformation and activate NF-κB

1997 • 397 citations

Caveolin Is Palmitoylated on Multiple Cysteine Residues

1995 • 356 citations

Activation of the p38 Mitogen-activated Protein Kinase Pathway by Epstein-Barr Virus-encoded Latent Membrane Protein 1 Coregulates Interleukin-6 and Interleukin-8 Production

1999 • 347 citations

Signalling functions of protein palmitoylation

1998 • 328 citations

Integral membrane protein 2 of Epstein—barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases

1995 • 318 citations

Epstein-Barr Virus LMP2A Transforms Epithelial Cells, Inhibits Cell Differentiation, and Activates Akt

2000 • 279 citations

Epstein-Barr virus-encoded protein found in plasma membranes of transformed cells

1985 • 274 citations

Activation of the cJun N-terminal kinase (JNK) pathway by the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1)

1998 • 269 citations

An integral membrane protein (LMP2) blocks reactivation of Epstein-Barr virus from latency following surface immunoglobulin crosslinking.

1994 • 262 citations

Phosphoinositides and phosphoinositide-utilizing enzymes in detergent-insoluble lipid domains.

1996 • 246 citations

The Immunoreceptor Tyrosine-Based Activation Motif of Epstein–Barr Virus LMP2A Is Essential for Blocking BCR-Mediated Signal Transduction

1997 • 235 citations

Orientation and patching of the latent infection membrane protein encoded by Epstein-Barr virus

1986 • 232 citations

Role of the TRAF Binding Site and NF-κB Activation in Epstein-Barr Virus Latent Membrane Protein 1-Induced Cell Gene Expression

1998 • 229 citations

Membrane rafts and signaling by the multichain immune recognition receptors

2000 • 226 citations

The Epstein–Barr virus LMP1 amino acid sequence that engages tumor necrosis factor receptor associated factors is critical for primary B lymphocyte growth transformation

1997 • 224 citations

Epstein-Barr virus latent membrane protein transactivates the human immunodeficiency virus type 1 long terminal repeat through induction of NF-kappa B activity

1992 • 211 citations

Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Activates the JNK Pathway through Its Extreme C Terminus via a Mechanism Involving TRADD and TRAF2

1999 • 208 citations

Sequence variation in the Epstein--Barr virus latent membrane protein 1

1994 • 186 citations

CD40 signaling in human dendritic cells is initiated within membrane rafts

2000 • 183 citations

A second Epstein-Barr virus membrane protein (LMP2) is expressed in latent infection and colocalizes with LMP1

1990 • 180 citations

Palmitoylation of the HIV-1 envelope glycoprotein is critical for viral infectivity

2000 • 179 citations

Essential Role of CD8 Palmitoylation in CD8 Coreceptor Function

2000 • 178 citations

Characterization of LMP-1's association with TRAF1, TRAF2, and TRAF3

1997 • 171 citations

An Animal Model for Acute and Persistent Epstein-Barr Virus Infection

1997 • 171 citations

Epstein-Barr virus LMP1 induction of the epidermal growth factor receptor is mediated through a TRAF signaling pathway distinct from NF-kappaB activation

1997 • 167 citations

Epstein–Barr Virus Coopts Lipid Rafts to Block the Signaling and Antigen Transport Functions of the BCR

2001 • 159 citations

Latent Membrane Protein 2A-Mediated Effects on the Phosphatidylinositol 3-Kinase/Akt Pathway

2000 • 150 citations

Activation of the small GTPase Cdc42 by the inflammatory cytokines TNFα and IL-1, and by the Epstein-Barr virus transforming protein LMP1

1999 • 146 citations

The Epstein-Barr Virus Oncoprotein Latent Membrane Protein 1 Engages the Tumor Necrosis Factor Receptor-Associated Proteins TRADD and Receptor-Interacting Protein (RIP) but Does Not Induce Apoptosis or Require RIP for NF-κB Activation

1999 • 145 citations

Transient Translocation of the B Cell Receptor and Src Homology 2 Domain-Containing Inositol Phosphatase to Lipid Rafts: Evidence Toward a Role in Calcium Regulation

2000 • 136 citations

An Epstein-Barr virus transformation-associated membrane protein interacts with src family tyrosine kinases

1992 • 135 citations

Tyrosine 112 of Latent Membrane Protein 2A Is Essential for Protein Tyrosine Kinase Loading and Regulation of Epstein-Barr Virus Latency

1998 • 134 citations

Physical and Functional Interaction of Filamin (Actin-binding Protein-280) and Tumor Necrosis Factor Receptor-associated Factor 2

2000 • 131 citations

Localization of the Major NF-κB-activating Site and the Sole TRAF3 Binding Site of LMP-1 Defines Two Distinct Signaling Motifs

1997 • 131 citations

An Epstein-Barr virus transforming protein associates with vimentin in lymphocytes.

1987 • 121 citations

The LMP2A ITAM Is Essential for Providing B Cells with Development and Survival Signals In Vivo

2000 • 120 citations

The truncated form of the Epstein-Barr virus latent-infection membrane protein expressed in virus replication does not transform rodent fibroblasts

1988 • 119 citations

A fusion of the EBV latent membrane protein-1 (LMP1) transmembrane domains to the CD40 cytoplasmic domain is similar to LMP1 in constitutive activation of epidermal growth factor receptor expression, nuclear factor-kappa B, and stress-activated protein kinase.

1998 • 113 citations

Identification of latent membrane protein 2A (LMP2A) domains essential for the LMP2A dominant-negative effect on B-lymphocyte surface immunoglobulin signal transduction

1996 • 103 citations

Deletion of DNA encoding the first five transmembrane domains of Epstein-Barr virus latent membrane proteins 2A and 2B

1993 • 100 citations

A Fusion of the EBV Latent Membrane Protein-1 (LMP1) Transmembrane Domains to the CD40 Cytoplasmic Domain Is Similar to LMP1 in Constitutive Activation of Epidermal Growth Factor Receptor Expression, Nuclear Factor-κB, and Stress-Activated Protein Kinase

1998 • 98 citations

The only domain which distinguishes Epstein-Barr virus latent membrane protein 2A (LMP2A) from LMP2B is dispensable for lymphocyte infection and growth transformation in vitro; LMP2A is therefore nonessential

1992 • 97 citations

Comparative analysis identifies conserved tumor necrosis factor receptor-associated factor 3 binding sites in the human and simian Epstein-Barr virus oncogene LMP1

1996 • 93 citations

Transformation by the oncogenic latent membrane protein correlates with its rapid turnover, membrane localization, and cytoskeletal association

1991 • 91 citations

The amino-terminus and membrane-spanning domains of LMP-1 inhibit cell proliferation

2000 • 67 citations

MIP-T3, a Novel Protein Linking Tumor Necrosis Factor Receptor-associated Factor 3 to the Microtubule Network

2000 • 64 citations

Phenotypes of Epstein-Barr virus LMP1 deletion mutants indicate transmembrane and amino-terminal cytoplasmic domains necessary for effects in B-lymphoma cells

1992 • 64 citations

The 30-Base-Pair Deletion in Chinese Variants of the Epstein-Barr Virus LMP1 Gene Is Not the Major Effector of Functional Differences between Variant LMP1 Genes in Human Lymphocytes

1998 • 57 citations

High Concentration of the EBV Latent Membrane Protein 1 in Glycosphingolipid-Rich Complexes from both Epithelial and Lymphoid Cells

1997 • 51 citations

An Epstein-Barr Virus Transforming Protein Associates with Vimentin in Lymphocytes

1987 • 48 citations

Evidence of LMP1-TRAF3 interactions in glycosphingolipid-rich complexes of lymphoblastoid and nasopharyngeal carcinoma cells

1999 • 45 citations

Epstein-Barr virus latent membrane protein: induction of B-cell activation antigens and membrane patch formation does not require vimentin

1989 • 37 citations

Epstein--Barr virus types 1 and 2 have nearly identical LMP-1 transforming genes

1994 • 29 citations

Functional analysis of different LMP1 proteins isolated from Epstein–Barr virus-positive carriers

1999 • 18 citations