The only domain which distinguishes Epstein-Barr virus latent membrane protein 2A (LMP2A) from LMP2B is dispensable for lymphocyte infection and growth transformation in vitro; LMP2A is therefore nonessential

Structural features in eukaryotic mRNAs that modulate the initiation of translation.

1991 • 1,849 citations

An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells

1985 • 1,257 citations

Release of Infectious Epstein-Barr Virus by Transformed Marmoset Leukocytes

1973 • 960 citations

Expression of Epstein–Barr Virus Transformation–Associated Genes in Tissues of Patients with EBV Lymphoproliferative Disease

1989 • 803 citations

Expression of Epstein-Barr virus latent gene products in tumour cells of Hodgkin's disease

1991 • 718 citations

Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation

1987 • 648 citations

Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23

1990 • 585 citations

Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

1987 • 567 citations

Genetic analysis of immortalizing functions of Epstein–Barr virus in human B lymphocytes

1989 • 553 citations

Epstein-Barr virus in nasal T-cell lymphomas in patients with lethal midline granuloma

1990 • 544 citations

Identification of target antigens for the human cytotoxic T cell response to Epstein-Barr virus (EBV): implications for the immune control of EBV-positive malignancies.

1992 • 519 citations

Epstein-Barr virus latent gene transcription in nasopharyngeal carcinoma cells: coexpression of EBNA1, LMP1, and LMP2 transcripts

1992 • 493 citations

Epstein-Barr virus nuclear protein 2 is a key determinant of lymphocyte transformation.

1989 • 491 citations

Association of B Cell Antigen Receptor with Protein Tyrosine Kinase Lyn

1991 • 471 citations

Epstein-Barr Virus: Transformation, Cytopathic Changes, and Viral Antigens in Squirrel Monkey and Marmoset Leukocytes

1972 • 441 citations

Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases.

1991 • 433 citations

Demonstration of monoclonal EBV genomes in Hodgkin's disease and Ki-1- positive anaplastic large cell lymphoma by combined Southern blot and in situ hybridization [see comments]

1989 • 422 citations

Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domain

1987 • 410 citations

Epstein-Barr virus latent infection membrane protein alters the human B-lymphocyte phenotype: deletion of the amino terminus abolishes activity

1988 • 403 citations

Establishment and characterization of an Epstein-Barr virus (EBC)-negative lymphoblastoid B cell line (BJA-B) from an exceptional, EBV-genome-negative African Burkitt's lymphoma.

1975 • 390 citations

Epstein-Barr virus (EBV)-associated lymphoproliferative disease in the SCID mouse model: implications for the pathogenesis of EBV-positive lymphomas in man.

1991 • 317 citations

Early events in Epstein-Barr virus infection of human B lymphocytes

1991 • 297 citations

Malignant Lymphoma in Cottontop Marmosets after Inoculation with Epstein-Barr Virus

1973 • 290 citations

Transformation of Balb 3T3 cells by the BNLF-1 gene of Epstein-Barr virus.

1988 • 280 citations

Differences Between Laboratory Strains of Epstein-Barr Virus Based on Immortalization, Abortive Infection, and Interference

1974 • 279 citations

Detection of ebv gene expression in reed‐sternberg cells of Hodgkin's disease

1990 • 279 citations

CD3-negative lymphoproliferative disease of granular lymphocytes containing Epstein-Barr viral DNA.

1989 • 275 citations

Epstein-Barr virus-encoded protein found in plasma membranes of transformed cells

1985 • 274 citations

Epstein-Barr virus latent gene expression in uncultured peripheral blood lymphocytes

1992 • 258 citations

Recombinant Epstein-Barr virus with small RNA (EBER) genes deleted transforms lymphocytes and replicates in vitro.

1991 • 220 citations

A Survey of Epstein-Barr Virus DNA in Lymphoid Tissue: Frequent Detection in Hodgkin’s Disease

1989 • 219 citations

Clonal transformation of adult human leukocytes by Epstein-Barr virus

1977 • 213 citations

Non-immortalizing P3J-HR-1 Epstein-Barr virus: a deletion mutant of its transforming parent, Jijoye

1982 • 204 citations

Molecular genetic analysis of lymphoid tumors arising after organ transplantation.

1989 • 186 citations

Consistent transcription of the Epstein-Barr virus LMP2 gene in nasopharyngeal carcinoma

1992 • 183 citations

A second Epstein-Barr virus membrane protein (LMP2) is expressed in latent infection and colocalizes with LMP1

1990 • 180 citations

Potential positive and negative autoregulation of p60c-src by intermolecular autophosphorylation.

1988 • 176 citations

Two related Epstein-Barr virus membrane proteins are encoded by separate genes

1989 • 161 citations

An Epstein-Barr virus protein associated with cell growth transformation interacts with a tyrosine kinase

1991 • 152 citations

Epstein-Barr virus DNA. IX. Variation among viral DNAs from producer and nonproducer infected cells

1981 • 149 citations

New Epstein–Barr virus variants from cellular subclones of P3J-HR-1 Burkitt lymphoma

1982 • 148 citations

Altered sites of tyrosine phosphorylation in pp60c-src associated with polyomavirus middle tumor antigen.

1986 • 147 citations

Deletion of the Nontransforming Epstein-Barr Virus Strain P3HR-1 Causes Fusion of the Large Internal Repeat to the DS _L Region

1982 • 145 citations

Biological differences between epstein-barr virus (EBV) strains with regard to lymphocyte transforming ability, superinfection and antigen induction

1975 • 143 citations

An Epstein-Barr virus transformation-associated membrane protein interacts with src family tyrosine kinases

1992 • 135 citations

BHRF1, the Epstein-Barr virus gene with homology to Bc12, is dispensable for B-lymphocyte transformation and virus replication

1991 • 128 citations

Use of second-site homologous recombination to demonstrate that Epstein-Barr virus nuclear protein 3B is not important for lymphocyte infection or growth transformation in vitro

1992 • 126 citations

The nature of Hodgkin and Reed-Sternberg cells, their association with EBV, and their relationship to anaplastic large-cell lymphoma

1991 • 123 citations

The truncated form of the Epstein-Barr virus latent-infection membrane protein expressed in virus replication does not transform rodent fibroblasts

1988 • 119 citations

hu‐PBL‐SCID Mice: A Model for Human Immune Function, AIDS, and Lymphomagenesis

1991 • 118 citations

Correlation of the expression of Epstein-Barr virus latent membrane protein and in situ hybridization with biotinylated BamHI-W probes in Hodgkin's disease.

1992 • 108 citations

Organization of the Epstein-Barr virus DNA molecule. III. Location of the P3HR-1 deletion junction and characterization of the NotI repeat units that form part of the template for an abundant 12-O-tetradecanoylphorbol-13-acetate-induced mRNA transcript

1983 • 104 citations

Epstein-Barr virus DNA XII. A variable region of the Epstein-Barr virus genome is included in the P3HR-1 deletion

1982 • 85 citations

The Terminal Protein Gene 2 of Epstein-Barr Virus Is Transcribed from a Bidirectional Latent Promoter Region

1989 • 79 citations

Differences between laboratory strains of Epstein-Barr virus based on immortalization, abortive infection and interference.

1975 • 57 citations

Second-site homologous recombination in Epstein-Barr virus: insertion of type 1 EBNA 3 genes in place of type 2 has no effect on in vitro infection

1992 • 55 citations

Identification of Epstein-Barr virus terminal protein 1 (TP1) in extracts of four lymphoid cell lines, expression in insect cells, and detection of antibodies in human sera

1990 • 51 citations

Altered Sites of Tyrosine Phosphorylation in pp60^c-src Associated with Polyomavirus Middle Tumor Antigen

1986 • 48 citations

Epstein-Barr virus (EBV) recombinants: use of positive selection markers to rescue mutants in EBV-negative B-lymphoma cells

1991 • 42 citations

Epstein-Barr virus latent membrane protein: induction of B-cell activation antigens and membrane patch formation does not require vimentin

1989 • 37 citations

The nature of Hodgkin and Reed-Sternberg cells, their association with EBV, and their relationship to anaplastic large-cell lymphoma

1991 • 34 citations

Composite Hodgkin's and Non-Hodgkin's lymphoma in a patient with acquired immune deficiency syndrome. In-situ demonstration of epstein–barr virus

1990 • 31 citations

Characterization of the BNLF-1 Oncogene of Epstein-Barr Virus

1989 • 10 citations