Transfection with γ-glutamyl transpeptidase enhances recovery from glutathione depletion using extracellular glutathione

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1966 • 26,261 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

[48] Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples

1981 • 1,564 citations

A Kinetic Photometric Method for Serum γ-Glutamyl Transpeptidase

1969 • 1,222 citations

Regulation of cellular glutathione

1989 • 851 citations

Glutathione and Related γ-Glutamyl Compounds: Biosynthesis and Utilization

1976 • 846 citations

Regulation of gamma-glutamyl-cysteine synthetase by nonallosteric feedback inhibition by glutathione.

1975 • 729 citations

Glutathione: interorgan translocation, turnover, and metabolism.

1979 • 601 citations

γ-Glutamyl transpeptidase: catalytic, structural and functional aspects

1981 • 442 citations

Analysis of adenovirus transforming proteins from early regions 1A and 1B with antisera to inducible fusion antigens produced in Escherichia coli

1984 • 349 citations

Gamma-glutamyl transpeptidase – its role in hepatocarcinogenesis

1985 • 313 citations

The liver: Biology and pathobiology

1988 • 312 citations

Leukotriene D: a slow reacting substance from rat basophilic leukemia cells.

1980 • 301 citations

Intracellular cysteine delivery system that protects against toxicity by promoting glutathione synthesis.

1982 • 286 citations

γ-Glutamyl Transpeptidase in Transplantable, Chemically Induced Rat Hepatomas and “Spontaneous” Mouse Hepatomas<xref ref-type="fn" rid="FN2">2</xref>

1972 • 238 citations

Glutathione conjugate mediated toxicities*1

1990 • 228 citations

Oxygen toxicity: augmentation of antioxidant defense mechanisms in rat lung

1976 • 216 citations

HISTOCHEMICAL DEMONSTRATION OF A GAMMA-GLUTAMYL TRANSPEPTIDASE-LIKE ACTIVITY

1962 • 174 citations

Exogenous glutathione protects intestinal epithelial cells from oxidative injury.

1986 • 173 citations

Induction of γ-glutamyl transpeptidase in cultured cerebral endothelial cells by a product released by astrocytes

1987 • 164 citations

Glutathione uptake and protection against oxidative injury in isolated kidney cells

1988 • 152 citations

Protection against paraquat-induced injury by exogenous GSH in pulmonary alveolar type II cells

1986 • 146 citations

gamma-Glutamyl transpeptidase, a lymphoid cell-surface marker: relationship to blastogenesis, differentiation, and neoplasia.

1976 • 123 citations

Mutagenicity of Glutathione and Cysteine in the Ames Test

1983 • 122 citations

On the Cycles of Glutathione Metabolism and Transport

1981 • 120 citations

Intracellular delivery of cysteine

1987 • 100 citations

Preparation of mammalian plasma membranes by aqueous two-phase partition.

1989 • 97 citations

Overexpressed human metallothionein IIA gene protects Chinese hamster ovary cells from killing by alkylating agents.

1990 • 96 citations

Cloning and nucleotide sequence of human gamma-glutamyl transpeptidase.

1988 • 89 citations

Modulation of endothelial GSH concentrations: effect of exogenous GSH and GSH monoethyl ester

1989 • 85 citations

Identification of a human gamma-glutamyl cleaving enzyme related to, but distinct from, gamma-glutamyl transpeptidase.

1991 • 77 citations

Glutathione biosynthesis in the isolated perfused rat lung: utilization of extracellular glutathione

1984 • 71 citations

Increase in endothelial cell glutathione and precursor amino acid uptake by diethyl maleate and hyperoxia

1989 • 68 citations

An examination of the relative resistances to aflatoxin B¹ and susceptibilities to γ-glutamyl p-phenylene diamine mustard of γ-glutamyl transferase negative and positive cell lines

1981 • 60 citations

Histochemical demonstration of enhanced glutathione content in enzyme-altered islands induced by carcinogens in rat liver.

1980 • 58 citations

Bacteriophage lambda vector for transducing a cDNA clone library into mammalian cells.

1985 • 57 citations

Oxidative metabolism of glutathione by γ-glutamyl transpeptidase and peroxisome proliferation: the relevance to hepatocarcinogenesis. A hypothesis

1991 • 47 citations

In vivo modulation of rat hepatic γ-glutamyltransferase activity by glucocorticoids

1980 • 36 citations

Gamma-glutamyltransferase activity of liver plasma membrane: Induction following chronic alcohol consumption

1981 • 35 citations

Renal γ-glutamyl transpeptidases: Influence of glycosylation on the electrophoretic behavior and molecular weights of their subunits

1986 • 34 citations

High-level expression of enzymatically active mature human gamma-glutamyltransferase in transgenic V79 Chinese hamster cells.

1991 • 31 citations

A human hepatoma cell line expresses a single-chain form of gamma-glutamyl transpeptidase.

1987 • 29 citations

Mechanism and relevance of glutathione mutagenicity

1986 • 25 citations

Induction of γ-glutamyl transpeptidase mRNA by aflatoxin B₁ and ethoxyquin in rat liver

1987 • 23 citations

Induction of γ-glutamyl transpeptidase in primary cultures of normal rat hepatocytes by liver tumor promoters and structurally related compounds

1985 • 23 citations

Glutathione mutagenesis in Salmonella typhimurium TA100: Dependence on a single enzyme, γ-glutamyltranspeptidase

1987 • 19 citations

Expression of rat renal gamma — glutamyltransferase cDNA in Escherichia coli

1989 • 15 citations

Exogenous glutathione induces sister chromatid exchanges, clastogenicity and endoreduplication in V79-E Chinese hamster cells

1985 • 13 citations

The mechanism of cytogenetic genotoxicity of exogenous glutathione in V-79 cells in vitro?implication of hydrogen peroxide and general traits of oxidative chromosome damage

1988 • 12 citations

Transfection of cytochrome P450 cDNAs into mammalian cells used in mutation and transformation assays.

1990 • 4 citations