Intracellular cysteine delivery system that protects against toxicity by promoting glutathione synthesis.

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues

1969 • 6,007 citations

Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione.

1973 • 1,717 citations

Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine).

1979 • 1,680 citations

Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism.

1973 • 1,467 citations

Chemistry of the amino acids

1961 • 1,404 citations

Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo.

1973 • 1,174 citations

Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system

1971 • 808 citations

Regulation of gamma-glutamyl-cysteine synthetase by nonallosteric feedback inhibition by glutathione.

1975 • 729 citations

Glutathione: interorgan translocation, turnover, and metabolism.

1979 • 601 citations

Acetaminophen-induced hepatic necrosis. 3. Cytochrome P-450-mediated covalent binding in vitro.

1973 • 500 citations

SPECIFICITY OF AMINO ACID ACYLASES

1952 • 349 citations

Glutathione export by human lymphoid cells: depletion of glutathione by inhibition of its synthesis decreases export and increases sensitivity to irradiation.

1981 • 230 citations

Evidence for impairment of transsulfuration pathway in cirrhosis

1981 • 229 citations

Glutathione depletion sensitizes tumor cells to oxidative cytolysis.

1982 • 214 citations

Stimulation of hepatic glutathione formation by administration of L-2-oxothiazolidine-4-carboxylate, a 5-oxo-L-prolinase substrate.

1981 • 199 citations

Inhibition of glutathione synthesis as a chemotherapeutic strategy for trypanosomiasis.

1981 • 140 citations

On the Cycles of Glutathione Metabolism and Transport

1981 • 120 citations

Cytotoxicity of cysteine in culture media

1976 • 92 citations

A Survey of Inborn Errors of Amino Acid Metabolism and Transport in Man

1981 • 81 citations

Morphological changes in rat brain induced byl-cysteine injection in newborn animals

1981 • 78 citations

Quantitative nutritional studies with water-soluble, chemically defined diets. III. Individual amino acids as sources of “non-essential” nitrogen

1957 • 73 citations

N-FORMYLCYSTEINE SYNTHESIS IN MITOCHONDRIA FROM FORMALDEHYDE AND l-CYSTEINE VIA THIAZOLIDINECARBOXYLIC ACID

1957 • 70 citations

Formation and metabolism of a glutathione-S-conjugate in isolated rat liver and kidney cells

1978 • 70 citations

Effects of methionine sulfoximine analogs on the synthesis of glutamine and glutathione: possible chemotherapeutic implications.

1979 • 64 citations

Depletion of glutathione selectively inhibits synthesis of leukotriene C by macrophages.

1981 • 61 citations

Prodrugs of L-cysteine as liver-protective agents. 2(R,S)-methylthiazolidine-4(R)-carboxylic acid (MTCA), a latent cysteine

1982 • 55 citations

The Metabolic Formation and Utilization of 5‐Oxo‐ <scp>L</scp> ‐proline ( <scp>L</scp> ‐Pyroglutamate, <scp>L</scp> ‐Pyrrolidone Carboxylate)

1975 • 46 citations

The Replacement by Thiazolidinecarboxylic Acid of Exogenous Cystine and Cysteine

1958 • 42 citations

5-Oxoprolinase (l-Pyroglutamate Hydrolase) in Higher Plants

1978 • 33 citations

Sulfur Amino Acid Requirements of Immature Beagle Dogs

1981 • 28 citations