Epigenetic regulation of microRNA-370 by interleukin-6 in malignant human cholangiocytes

MicroRNA signatures in human cancers

2006 • 7,358 citations

TM4: A Free, Open-Source System for Microarray Data Management and Analysis

2003 • 4,724 citations

Combinatorial microRNA target predictions

2005 • 4,543 citations

Human MicroRNA Targets

2004 • 3,702 citations

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

2003 • 3,098 citations

Comprehensive analysis of CpG islands in human chromosomes 21 and 22

2002 • 1,485 citations

Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells

2006 • 1,325 citations

DNA methylation and gene silencing in cancer

2005 • 1,110 citations

Involvement of Human Micro-RNA in Growth and Response to Chemotherapy in Human Cholangiocarcinoma Cell Lines

2006 • 970 citations

Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues.

2006 • 789 citations

A combined computational-experimental approach predicts human microRNA targets

2004 • 776 citations

MicroRNAs and chromosomal abnormalities in cancer cells

2006 • 263 citations

Interleukin-6 Contributes to Growth in Cholangiocarcinoma Cells by Aberrant Promoter Methylation and Gene Expression

2006 • 223 citations

Interleukin 6 Supports the Maintenance of p53 Tumor Suppressor Gene Promoter Methylation

2005 • 219 citations

Cholangiocarcinoma

2006 • 218 citations

Inhibition of interleukin 6-mediated mitogen-activated protein kinase activation attenuates growth of a cholangiocarcinoma cell line

1999 • 208 citations

Multiple Mitogen-Activated Protein Kinase Signaling Pathways Connect the Cot Oncoprotein to the c-junPromoter and to Cellular Transformation

2000 • 198 citations

Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation.

1993 • 171 citations

Interleukin-6 Regulation of the Human DNA Methyltransferase (HDNMT) Gene in Human Erythroleukemia Cells

2001 • 158 citations

Diverse Toll-like receptors utilize Tpl2 to activate extracellular signal-regulated kinase (ERK) in hemopoietic cells

2006 • 142 citations

Over-expression of interleukin-6 enhances cell survival and transformed cell growth in human malignant cholangiocytes

2005 • 119 citations

Overexpression of the Tpl-2/Cot oncogene in human breast cancer

1999 • 90 citations

Interleukin‐6 functions as an autocrine growth factor in a cholangiocarcinoma cell line

1994 • 90 citations

IL-6 activates serum and glucocorticoid kinase via p38α mitogen-activated protein kinase pathway

2005 • 75 citations

Involvement of p38 mitogen-activated protein kinase signaling in transformed growth of a cholangiocarcinoma cell line

2001 • 67 citations

The Oncogenic Protein Kinase Tpl-2/Cot Contributes to Epstein-Barr Virus-Encoded Latent Infection Membrane Protein 1-Induced NF-κB Signaling Downstream of TRAF2

2002 • 59 citations

The human cot proto-oncogene encodes two protein serine/threonine kinases with different transforming activities by alternative initiation of translation.

1993 • 57 citations

Genomic organization and expression of Tpl-2 in normal cells and Moloney murine leukemia virus-induced rat T-cell lymphomas: activation by provirus insertion

1993 • 54 citations

Translational regulation by p38 mitogen-activated protein kinase signaling during human cholangiocarcinoma growth

2003 • 36 citations

Identification of the cells expressing cot proto-oncogene mRNA

1995 • 26 citations