Phosphorylation of splicing factor SF1 on Ser20 by cGMP-dependent protein kinase regulates spliceosome assembly

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polycrylamide to nitrocellulose

1984 • 2,553 citations

Nucleocytoplasmic transport: signals, mechanisms and regulation

1997 • 987 citations

Clonal cell lines from the rat central nervous system

1974 • 727 citations

THE STRUCTURE AND FUNCTION OF PROTEINS INVOLVED IN MAMMALIAN PRE-mRNA SPLICING

1996 • 687 citations

The superfamily of arginine/serine-rich splicing factors.

1995 • 671 citations

SR proteins and splicing control.

1996 • 668 citations

The dynamics of a pre-mRNA splicing factor in living cells

1997 • 604 citations

Cloning and domain structure of the mammalian splicing factor U2AF

1992 • 566 citations

The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution.

1996 • 559 citations

A serine kinase regulates intracellular localization of splicing factors in the cell cycle

1994 • 511 citations

Defective smooth muscle regulation in cGMP kinase I-deficient mice

1998 • 510 citations

A specific subset of SR proteins shuttles continuously between the nucleus and the cytoplasm

1998 • 476 citations

Intestinal Secretory Defects and Dwarfism in Mice Lacking cGMP-Dependent Protein Kinase II

1996 • 405 citations

Primary structure of the human splicing factor asf reveals similarities with drosophila regulators

1991 • 357 citations

Cross-Intron Bridging Interactions in the Yeast Commitment Complex Are Conserved in Mammals

1997 • 342 citations

The Splicing Factor BBP Interacts Specifically with the Pre-mRNA Branchpoint Sequence UACUAAC

1997 • 327 citations

SRPK2: A Differentially Expressed SR Protein-specific Kinase Involved in Mediating the Interaction and Localization of Pre-mRNA Splicing Factors in Mammalian Cells

1998 • 306 citations

Cyclic GMP‐Dependent Protein Kinase and Cellular Signaling in the Nervous System

1997 • 288 citations

Initial splice-site recognition and pairing during pre-mRNA splicing

1996 • 281 citations

Interaction of U2AF ⁶⁵ RS Region with Pre-mRNA of Branch Point and Promotion Base Pairing with U2 snRNA

1996 • 279 citations

Dynamin GTPase regulated by protein kinase C phosphorylation in nerve terminals

1993 • 272 citations

A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition

1998 • 253 citations

Regulation of adenovirus alternative RNA splicing by dephosphorylation of SR proteins

1998 • 220 citations

Phosphorylation-dephosphorylation differentially affects activities of splicing factor ASF/SF2

1998 • 200 citations

Phosphorylation of spliceosomal protein SAP 155 coupled with splicing catalysis

1998 • 182 citations

In Vivo Regulation of Alternative Pre-mRNA Splicing by the Clk1 Protein Kinase

1997 • 169 citations

Coupling of signal transduction to alternative pre-mRNA splicing by a composite splice regulator

1998 • 162 citations

WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: The proline glycine and methionine-rich motif

1998 • 157 citations

[10] Design and use of peptide substrates for protein kinases

1991 • 125 citations

Determination of Cyclic Nucleotide-Dependent Protein Kinase Substrate Specificity by the Use of Peptide Libraries on Cellulose Paper

1995 • 123 citations

Regulation of Gene Expression by Cyclic GMP-Dependent Protein Kinase Requires Nuclear Translocation of the Kinase: Identification of a Nuclear Localization Signal

1997 • 121 citations

Cyclic-GMP-Dependent Protein Kinase Inhibits the Ras/Mitogen-Activated Protein Kinase Pathway

1998 • 109 citations

Three protein factors (SF1, SF3 and U2AF) function in pre-splicing complex formation in addition to snRNPs.

1991 • 104 citations

Conservation of functional domains involved in RNA binding and protein–protein interactions in human and Saccharomyces cerevisiae pre-mRNA splicing factor SF1

1998 • 98 citations

A Selective Precipitation Purification Procedure for Multiple Phosphoseryl-Containing Peptides and Methods for Their Identification

1994 • 97 citations

Cyclin E Associates with Components of the Pre-mRNA Splicing Machinery in Mammalian Cells

1998 • 91 citations

Regulation of Alternative Splicing of Protein Kinase Cβ by Insulin

1995 • 90 citations

Purification of splicing factor SF1, a heat-stable protein that functions in the assembly of a presplicing complex.

1992 • 86 citations

Depolarisation‐Dependent Protein Phosphorylation in Rat Cortical Synaptosomes: Factors Determining the Magnitude of the Response

1983 • 83 citations

A phenylalanine in peptide substrates provides for selectivity between cGMP- and cAMP-dependent protein kinases.

1992 • 80 citations

Rapid and selective modification of phosphoserine residues catalysed by Ba2+ ions for their detection during peptide microsequencing

1991 • 74 citations

Depolarization‐Dependent Protein Phosphorylation in Rat Cortical Synaptosomes: Characterization of Active Protein Kinases by Phosphopeptide Analysis of Substrates

1986 • 64 citations

Differential stimulation of protein kinase C activity by phorbol ester or calcium/phosphatidylserine in vitro and in intact synaptosomes.

1992 • 60 citations

The KH domain of the branchpoint sequence binding protein determines specificity for the pre-mRNA branchpoint sequence

1998 • 50 citations

Protein phosphatase 1 can modulate alternative 5′ splice site selection in a HeLa splicing extract

1994 • 47 citations

Cyclic GMP‐Dependent Protein Kinase Substrates in Rat Brain

1995 • 31 citations

Dephosphin, a 96 000 Da substrate of protein kinase C in synaptosomal cytosol, is phosphorylated in intact synaptosomes

1991 • 25 citations

Diverse modes of alternative splicing of human splicing factor SF1 deduced from the exon–intron structure of the gene

1998 • 16 citations