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Recent developments in the rational design of multivalent glycoconjugates

Data up to Jan 2025

Published1997
Citations101
References98

Total Citations Per Year

Abstract

References (98)

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1993 • 711 citations

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1995 • 574 citations

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1993 • 442 citations

Modern methods in carbohydrate synthesis

1997 • 394 citations

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1995 • 380 citations

Polyacrylamides Bearing Pendant α-Sialoside Groups Strongly Inhibit Agglutination of Erythrocytes by Influenza Virus: The Strong Inhibition Reflects Enhanced Binding through Cooperative Polyvalent Interactions

1996 • 335 citations

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1995 • 267 citations

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1993 • 256 citations

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1980 • 254 citations

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1994 • 219 citations

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1993 • 188 citations

New synthetic cluster ligands for galactose/N-acetylgalactosamine-specific lectin of mammalian liver

1984 • 178 citations

Neoglycoconjugates: Preparation and applications

1995 • 173 citations

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1995 • 154 citations

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1994 • 141 citations

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1992 • 140 citations

“Active” and “latent” thioglycosyl donors in oligosaccharide synthesis. Application to the synthesis of α-sialosides

1992 • 138 citations

Macromolecular recognition: Effect of multivalency in the inhibition of binding of yeast mannan to concanavalin A and pea lectins by mannosylated dendrimers

1996 • 138 citations

Ligand Recognition by E-Selectin: Synthesis, Inhibitory Activity and Conformational Analysis of Bivalent Sialyl Lewis x Analogs

1995 • 135 citations

Glycocoating of Oligovalent Amines: Synthesis of Thiourea‐Bridged Cluster Glycosides from Glycosyl Isothiocyanates

1996 • 130 citations

Cellular Mucins: Targets for Immunotherapy

2017 • 130 citations

Use of diethyl squarate for the coupling of oligosaccharide amines to carrier proteins and characterization of the resulting neoglycoproteins by MALDI-TOF mass spectrometry

1996 • 128 citations

Synthetic carbohydrate vaccines based on tumour-associated antigens

1995 • 123 citations

Studies on lectins XXXV. Water-soluble O-glycosyl polyacrylamide derivatives for specific precipitation of lectins

1978 • 119 citations

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1989 • 110 citations

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1987 • 109 citations

Multiple Sialyl Lewisx N‐Glycopeptides: Effective Ligands for E‐Selectin

1996 • 105 citations

Cellular Mucins: Targets for Immunotherapy

1994 • 102 citations

Glycopeptides bind MHC molecules and elicit specific T cell responses.

1993 • 98 citations

Synthetic vaccines: synthesis of a dimeric Tn antigen-lipopeptide conjugate that elicits immune responses against Tn-expressing glycoproteins

1994 • 95 citations

Sugar Calixarenes: Preparation of Calix[4]arenes Substituted at the Lower and Upper Rims with O‐Glycosyl Groups

1995 • 93 citations

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1996 • 82 citations

Carbohydrates in an Acidic Multivalent Assembly: Nanomolar P-Selectin Inhibitors

1996 • 77 citations

Synthesis of novel dendritic glycosides

1995 • 75 citations

Synthesis of Esterase‐resistant 9‐O‐Acetylated Polysialoside as Inhibitor of Influenza C Virus Hemagglutinin

1992 • 74 citations

Chemical and enzymatic synthesis of multivalent sialoglycopeptides

1994 • 73 citations

Inhibition of influenza A virus hemagglutinin and induction of interferon by synthetic sialylated glycoconjugates

1991 • 72 citations

Molecular recognition of bivalent sialosides by influenza virus

1991 • 71 citations

New strategy in glycopolymer syntheses. Preparation of antigenic water-soluble poly(acrylamide-co-p-acrylamidophenyl .beta.-lactoside)

1992 • 70 citations

Synthesis of protein conjugates and analogues of N-acetylneuraminic acid

1990 • 70 citations

Mild stereoselective syntheses of thioglycosides under PTC conditions and their use as active and latent glycosyl donors

1994 • 69 citations

Polysialosides scaffolded on p-Tert-butylcalix[4]arene

1996 • 68 citations

Synthesis of a Divalent Sialyl Lewis x O‐glycan, a Potent Inhibitor of Lymphocyte‐Endothelium Adhesion

1995 • 67 citations

Synthesis of antigenic copolymers of N-acetylneuraminic acid binding to wheat germ agglutinin and antibodies

1988 • 66 citations

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1995 • 65 citations

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1981 • 62 citations

Cell-Type Specific and Ligand Specific Enhancement of Cellular Uptake of Oligodeoxynucleoside Methylphosphonates Covalently Linked with a Neoglycopeptide, YEE(ah-GalNAc)3

1995 • 62 citations

Stereoselective phase transfer catalyzed syntheses of glycosyloxysuccinimides and their transformations into glycoprobes

1995 • 60 citations

Affinity Chromatography of Macromolecular Substances on Adsorbents Bearing Carbohydrate Ligands

1981 • 56 citations

Synthetic Glycoconjugates as Human Vaccines

1994 • 53 citations

Synthesis of hyper-branched dendritic lactosides

1995 • 52 citations

Soluble polymers for lectin-mediated drug targeting

1994 • 51 citations

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1991 • 49 citations

Synthesis of a tetravalent sialyl Lewis x glycan, a high-affinity inhibitor of L-selectin-mediated lymphocyte binding to endothelium

1996 • 48 citations

Expedient syntheses of neoglycoproteins using phase transfer catalysis and reductive amination as key reactions

1991 • 47 citations

Towards the development of antimicrobial drugs acting by inhibition of pathogen attachment to host cells: A need for polyvalency

1989 • 43 citations

Immobilized glycoconjugates for cell recognition studies

1984 • 43 citations

Synthesis of fragments of bacterial polysaccharides and their application for the preparation of synthetic antigens

1984 • 42 citations

Combined glycomimetic and multivalent strategies for the design of potent selectin antagonists

1996 • 40 citations

Michael addition as the key step in the syntheses of sialyloligosaccharide–protein conjugates from N-acryloylated glycopyranosylamines

1990 • 40 citations

First synthesis of N-linked-glycopeptoid as new glycopeptidomimetics

1995 • 40 citations

The Relevance of Neoglycoconjugates for Histology and Pathology.

1995 • 40 citations

Synthesis and lectin binding properties of dendritic mannopyranoside

1996 • 39 citations

An Aminated GDP-Fucose Analog Useful in the Fucosyltransferase Catalyzed Addition of Biological Probes onto Oligosaccharide Chains1

1995 • 38 citations

Synthesis of Neoglycoconjugates

1994 • 38 citations

Synthesis of glycosylated peptide templates containing 6′-O-phosphorylated mannose disaccharides and their binding to the cation-independent mannose 6-phosphate receptor

1994 • 37 citations

Versatile synthesis of bi- and tri-antennary galactose ligands: interaction with the Gal/GalNAc receptor of human hepatoma cells

1995 • 36 citations

Synthetic Glycoconjugates. 5. Polymeric Sugar Ligands Available for Determining the Binding Specificity of Lectins

1995 • 35 citations

Synthesis of new oligosaccharidyl-thio-β-cyclodextrins (CDS): a novel family of potent drug-targetting vectors.

1994 • 34 citations

Synthesis of divalent α-D-mannopyranosylated clusters having enhanced binding affinities towards concanavalin A and pea lectins

1996 • 31 citations

[19] Neoglycolipids: Probes in structure /function assignments to oligosaccharides

1994 • 28 citations

Synthesis of glycopolymers containing GM3-saccharide

1996 • 27 citations

Enzymic Synthesis of Octadecameric Saccharides of Multiply Branched Blood Group I-Type, Carrying Four Distal .alpha.1,3-Galactose or .beta.1,3-GlcNAc Residues

1995 • 27 citations

Strategies for the Synthesis and Screening of Glycoconjugates. 2. Covalent Immobilization for Flow Cytometry

1995 • 26 citations

Binding Modes of Mammalian Hepatic Gal/GalNAc Receptors

2007 • 26 citations

Zuckercalixarene: Synthese von Calix[4]arenen mit O‐Glycosylsubstituenten am oberen oder unteren Rand

1994 • 23 citations

Single step syntheses of lactosylated clusters by telomerizations

1994 • 21 citations

Synthesis of new glycopeptidomimetics based on N-substituted oligoglycine bearing an N-linked lactoside side-chain

1995 • 20 citations

Syntheses and transformations of glycohydrolase substrates into protein conjugates based on Michael additions

1991 • 19 citations

[8] Michael additions for syntheses of neoglycoproteins

1994 • 19 citations

Michael addition of poly-L-lysine to N-acryloylated sialosides. Syntheses of influenza A virus haemagglutinin inhibitor and group B meningococcal polysaccharide vaccinest

1993 • 19 citations

Custom-designed glycopolymer syntheses by terpolymerizations

1992 • 19 citations

Fluorescein-labeled O-glycosyloxyalkenyl-aminoalkenyl-acrylamide copolymers in lectin-saccharide binding studies

1991 • 17 citations

[24] Tailor-made glycopolymer syntheses

1994 • 17 citations

[27] Syntheses of clustered lactosides by telomerization

1994 • 14 citations

[24] Induction of rabbit immunoglobulin G antibodies against synthetic sialylated neoglycoproteins

1994 • 13 citations

Synthesis and Immunological Properties of Glycopeptide T-Cell Determinants

1993 • 12 citations

Phase transfer catalysis in carbohydrate chemistry

1997 • 11 citations

[22] Carbohydrate-lysyllysine conjugates as cell antiadhesion agents

1994 • 10 citations

Synthesis and carbon-13 n.m.r. spectroscopy of Man3 Lys2-raffinose conjugate

1982 • 6 citations

Oligosaccharide—Polyacrylamide Conjugates of Immunological Interest

1994 • 6 citations

Synthetic Probe for Study of Molecules Related to Selectin Family

1994 • 5 citations

[18] Replacement of glycosphingolipid ceramide residues by glycerolipid for microtiter plate assays

1994 • 4 citations

Synthesis of 8-aminooctyl glycopyranosides and of their conjugates with poly(l-glutamic acid) having a 2-(4-hydroxyphenyl) ethylamino group for radiolabeling

1993 • 2 citations

Preface

1994 • 1 citations

Cited By (0)

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Recent developments in the rational design of multivalent glycoconjugates (1997) – Topics in current chemistry | Metascience Observatory Explorer