Synthesis of a Divalent Sialyl Lewis x O‐glycan, a Potent Inhibitor of Lymphocyte‐Endothelium Adhesion

MLEV-17-based two-dimensional homonuclear magnetization transfer spectroscopy

1985 • 3,603 citations

A cell-surface molecule involved in organ-specific homing of lymphocytes

1983 • 1,515 citations

α4β7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1

1993 • 1,427 citations

α4 integrins mediate lymphocyte attachment and rolling under physiologic flow

1995 • 1,018 citations

Selectin ligands.

1994 • 943 citations

Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice

1994 • 835 citations

The three members of the selectin receptor family recognize a common carbohydrate epitope, the sialyl Lewis(x) oligosaccharide

1992 • 698 citations

An endothelial ligand for L-Selectin is a novel mucin-like molecule

1992 • 660 citations

Binding of L-Selectin to the Vascular Sialomucin CD34

1993 • 629 citations

Sequential contribution of L- and P-selectin to leukocyte rolling in vivo.

1995 • 597 citations

L-selectin-mediated lymphocyte rolling on MAdCAM-1

1993 • 540 citations

The selectins and their ligands

1994 • 478 citations

Lectin-like cell adhesion molecule 1 mediates leukocyte rolling in mesenteric venules in vivo

1991 • 473 citations

The role of alpha-lactalbumin and the A protein in lactose synthetase: a unique mechanism for the control of a biological reaction.

1968 • 459 citations

Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains

1994 • 397 citations

Chemical-enzymic synthesis and conformational analysis of sialyl Lewis X and derivatives

1992 • 388 citations

MAdCAM-1 has homology to immunoglobulin and mucin-like adhesion receptors and to IgA1

1993 • 383 citations

The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor

1995 • 358 citations

Protective effects of oligosaccharides in P-selectin-dependent lung injury

1993 • 319 citations

Structural and functional characterization of monomeric soluble P-selectin and comparison with membrane P-selectin

1993 • 297 citations

Structure of the O-Glycans in GlyCAM-1, an Endothelial-derived Ligand for L-selectin

1995 • 291 citations

The Asn‐linked carbohydrate chains of human Tamm‐Horsfall glycoprotein of one male

1992 • 288 citations

Characterization of a specific ligand for P-selectin on myeloid cells. A minor glycoprotein with sialylated O-linked oligosaccharides

1993 • 274 citations

The P-selectin glycoprotein ligand from human neutrophils displays sialylated, fucosylated, O-linked poly-N-acetyllactosamine.

1994 • 273 citations

P-selectin and vascular cell adhesion molecule 1 mediate rolling and arrest, respectively, of CD4+ T lymphocytes on tumor necrosis factor α-activated vascular endothelium under flow.

1995 • 223 citations

Oligosaccharides that mediate mammalian cell-cell adhesion

1993 • 197 citations

Identification of the Sulfated Monosaccharides of GlyCAM-1, an Endothelial-Derived Ligand for L-Selectin

1994 • 166 citations

Biological magnetic resonance

1991 • 146 citations

Ligand Recognition by E-Selectin: Synthesis, Inhibitory Activity and Conformational Analysis of Bivalent Sialyl Lewis x Analogs

1995 • 135 citations

Characterization of Sialyloligosaccharide Binding by Recombinant Soluble and Native Cell-associated CD22

1995 • 119 citations

Expression of sialyl-Lewis X, an E-selectin ligand, in inflammation, immune processes, and lymphoid tissues.

1992 • 113 citations

Enzymic synthesis of oligosaccharides terminating in the tumor-associated sialyl-Lewis-a determinant

1989 • 105 citations

De novo expression of endothelial sialyl Lewis(a) and sialyl Lewis(x) during cardiac transplant rejection: superior capacity of a tetravalent sialyl Lewis(x) oligosaccharide in inhibiting L-selectin-dependent lymphocyte adhesion.

1995 • 101 citations

Ligand recognition by E-selectin: analysis of conformation and activity of synthetic monomeric and bivalent sialyl Lewis X analogs

1993 • 95 citations

Further characterization of the interaction between L-selectin and its endothelial ligands

1992 • 76 citations

The solution conformation of the Le group

1991 • 74 citations

Multivalent sialyl-LeX: potent inhibitors of E-selectin-mediated cell adhesion; reagent for staining activated endothelial cells

1994 • 73 citations

Selective expression of sialyl-Lewis x and Lewis a epitopes, putative ligands for L-selectin, on peripheral lymph-node high endothelial venules.

1992 • 66 citations

Detection of beta-galactosyl(1 leads to 4)N-acetylglucosaminide alpha(2 leads to 3)-sialyltransferase activity in fetal calf liver and other tissues.

1981 • 66 citations

Specific Expression of a Complex Sialyl Lewis X Antigen on High Endothelial Venules of Human Lymph Nodes: Possible Candidate for L-Selectin Ligand

1993 • 65 citations

Purification of theN-acetylglucosaminide ?(1?3/4) fucosyltransferase of human milk

1989 • 57 citations

Characterization of high endothelial-like properties of peritubular capillary endothelium during acute renal allograft rejection.

1990 • 52 citations

Sialyl Lewis^x‐ and L‐selectin‐dependent site‐specific lymphocyte extravasation into renal transplants during acute rejection

1994 • 48 citations

Use of the “core-2”-N-acetylglucosaminyltransferase in the chemical-enzymatic synthesis of a sialyl-Lex-containing hexasaccharide found on O-linked glycoproteins

1993 • 37 citations

Wheat germ agglutinin chromatography of GlcNacβ1-3(GlcNAcβl-6)Gal and GlcNAcβ1-3(GlcNAcβ1-6)Galβ1-4GlcNAc, obtained by in vitro synthesis and by partial cleavage of teratocarcinoma poly-N-acetyllactosaminoglycans

1990 • 26 citations

Analysis of an initial step of T cell adhesion to endothelial monolayers under flow conditions.

1995 • 25 citations

Human liver and human placenta both contain CMP‐NeuAc:Galβ1→4GlcNAc‐R α2→3‐ as well as α2→6‐sialyltransferase activity

1992 • 17 citations

Syntheses of model oligosaccharides of biological significance. X.•Syntheses and NMR and mass spectral analysis of trideuteriomethyl di-3,6-O-(4-O-β-<scp>D</scp>-galactopyranosyl-2-acetamido-2-deoxy-β-<scp>D</scp>-glucopyranosyl)-β-<scp>D</scp>-galactopyranoside: the I antigen branchpoint penta- and tetrasaccharides and a related trisaccharide

1990 • 16 citations

Construction of linear GlcNAc?1-6Gal?1-OR type oligosaccharides by partial cleavage of GlcNAc?1-3(GlcNAc?1-6)Gal?1-OR sequences with jack bean ?-N-acetylhexosaminidase

1991 • 11 citations

Enzyme‐aided construction of medium‐sized alditols of complete O‐linked saccharides

1994 • 11 citations

Analysis of Linkage Monosaccharides in Human Teratocarcinoma Cell Glycopeptides: Paper Chromatographie Separation ofN-Acetylglucosaminitol andN-Acetylgalactosaminitol

1982 • 9 citations

A novel β‐N‐acetylglucosaminidase activity in hog gastric mucosal microsomes: Preferential hydrolysis of terminal GlcNAcß1‐3 linkages in GlcNAcß1‐3(GlcNAcß1‐6)Galß1‐GlcNAc, but GlcNAcß1‐6 linkages in GlcNAcß1‐3(GlcNAcß1‐6)Gal

1993 • 6 citations