“In vivo” activated splenic T cells are refractory to interleukin 2 growth “in vitro”

A rapid method for the isolation of functional thymus‐derived murine lymphocytes

1973 • 4,203 citations

The clonal selection theory of acquired immunity

1959 • 2,008 citations

Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*

1979 • 1,989 citations

The clonal selection theory of acquired immunity

1959 • 1,576 citations

T cell growth factor receptors. Quantitation, specificity, and biological relevance

1981 • 1,087 citations

The Interleukin-2 T-Cell System: A New Cell Growth Model

1984 • 935 citations

Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen.

1984 • 742 citations

Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cells

1985 • 613 citations

A monoclonal antibody discriminating between subsets of T and B cells.

1981 • 565 citations

Fine Specificity Analysis with Monoclonal Antibodies of Antigens Controlled by the Major Histocompatibility Complex and by the Qa/TL Region in Mice

1979 • 451 citations

Identification and initial characterization of a rat monoclonal antibody reactive with the murine interleukin 2 receptor-ligand complex.

1983 • 348 citations

A rat anti-mouse T4 monoclonal antibody (H129.19) inhibits the proliferation of Ia-reactive T cell clones and delineates two phenotypically distinct (T4+, Lyt-2,3-, and T4-, Lyt-2,3+) subsets among anti-Ia cytolytic T cell clones.

1984 • 308 citations

Cancer Immunotherapy Using Interleukin-2 and Interleukin-2-Activated Lymphocytes

1986 • 307 citations

Use of the Avidin-Biotin Complex for Specific Staining of Biological Membranes in Electron Microscopy

1974 • 269 citations

Expression and function of interleukin-2 receptors on immature thymocytes

1985 • 217 citations

Production and characterization of monoclonal antibodies to human interleukin 2: strategy and tactics.

1983 • 203 citations

Autonomous activation of B and T cells in antigen-free mice

1986 • 184 citations

Systemic administration of recombinant interleukin 2 stimulates in vivo lymphoid cell proliferation in tissues.

1985 • 136 citations

Reagents for Immunofluorescence and Their Use for Studying Lymphoid Cell Products

1979 • 113 citations

Absence of growth by most receptor-expressing fetal thymocytes in the presence of interleukin-2

1985 • 108 citations

Immunocompetent autoreactive B lymphocytes are activated cycling cells in normal mice.

1986 • 97 citations

Regulation of T cell autocrine growth. T4+ cells become refractory to interleukin 2.

1986 • 94 citations

A mouse IgM allotypic determinant (Igh-6.5) recognized by a monoclonal rat antibody.

1981 • 92 citations

Requirements for growth of immature thymocytes from fetal and adult mice in vitro

1986 • 78 citations

Two-step separation of human peripheral blood monocytes on discontinuous density gradients of colloidal silica-polyvinylpyrrolidinone

1977 • 77 citations

Quantitative studies on T cell diversity. I. Determination of the precursor frequencies for two types of streptococcus A-specific helper cells in nonimmune, polyclonally activated splenic T cells.

1980 • 75 citations

Natural effector T lymphocytes in normal mice.

1985 • 70 citations

Macrophages Suppress Direct B‐Cell Activation by Lipopolysaccharide

1975 • 49 citations

Quantitative studies on concanavalin A-induced, TCGF-reactive T cells. I. Correlation between proliferation and lectin-dependent cytolytic activity.

1981 • 46 citations

Does clonal selection occur among T cells?

1983 • 18 citations

Interleukin 2 receptor expression in unstimulated murine splenic T cells. Localization to L3T4+ cells and regulation by non-H-2-linked genes.

1986 • 17 citations

Lymphocyte‐mediated cytotoxicity against tumor cells. II. Characteristics and tissue distribution of concanavalin A‐ activated cytotoxic effector cells

1976 • 8 citations