Interleukin-10 gene transfer activates interferon-? and the interferon-?-inducible genesGbp-1/Mag-1 andMig-1 in mammary tumors

Macrophage deactivation by interleukin 10.

1991 • 1,253 citations

Distribution and cloning of eukaryotic mRNAs by means of differential display: refinements and optimization

1993 • 874 citations

Mig and IP-10: CXC chemokines that target lymphocytes

1997 • 802 citations

Biological properties of interleukin 10

1992 • 656 citations

Interleukin-10 (IL-10) inhibits the induction of nitric oxide synthase by interferon-γ in murine macrophages

1992 • 384 citations

Human Mig chemokine: biochemical and functional characterization.

1995 • 378 citations

A macrophage mRNA selectively induced by gamma-interferon encodes a member of the platelet factor 4 family of cytokines.

1990 • 302 citations

The CXC Chemokines IP-10 and Mig Are Necessary for IL-12-Mediated Regression of the Mouse RENCA Tumor

1998 • 295 citations

Mig, the Monokine Induced By Interferon-γ, Promotes Tumor Necrosis In Vivo

1997 • 251 citations

Interleukin‐10 production by human carcinoma cell lines and its relationship to interleukin‐6 expression

1993 • 245 citations

Interleukin-10 inhibits tumor metastasis through an NK cell-dependent mechanism.

1996 • 227 citations

Systemic administration of cellular IL-10 induces an effective, specific, and long-lived immune response against established tumors in mice.

1996 • 207 citations

Interleukin-10 prevents dendritic cell accumulation and vaccination with granulocyte-macrophage colony-stimulating factor gene-modified tumor cells.

1997 • 200 citations

The functional characterization of interleukin-10 receptor expression on human natural killer cells

1995 • 193 citations

Human IL-10 is a chemoattractant for CD8+ T lymphocytes and an inhibitor of IL-8-induced CD4+ T lymphocyte migration.

1993 • 184 citations

Local release of IL-10 by transfected mouse mammary adenocarcinoma cells does not suppress but enhances antitumor reaction and elicits a strong cytotoxic lymphocyte and antibody-dependent immune memory.

1995 • 180 citations

The role of CXC chemokines in the regulation of angiogenesis in non-small cell lung cancer

1997 • 161 citations

Antimetastatic and Antitumor Activities of Interleukin 10 in a Murine Model of Breast Cancer

1996 • 157 citations

Interleukin 10 suppresses tumor growth and metastasis of human melanoma cells: potential inhibition of angiogenesis.

1996 • 151 citations

The interferon-induced 67-kDa guanylate-binding protein (hGBP1) is a GTPase that converts GTP to GMP

1994 • 149 citations

Interleukin 10 transfected into Chinese hamster ovary cells prevents tumor growth and macrophage infiltration.

1993 • 140 citations

Interleukin-10 Inhibits Tumor Metastasis, Downregulates MHC Class I, and Enhances NK Lysis

1997 • 138 citations

Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP.

1991 • 125 citations

Elongation factor-1 alpha mRNA is selectively translated following mitogenic stimulation.

1994 • 117 citations

CD8 T cell clones inhibit antitumor T cell function by secreting IL-10.

1995 • 104 citations

Loss of Tumorigenicity and Increased Immunogenicity Induced by Interleukin-10 Gene Transfer in B16 Melanoma Cells

1996 • 83 citations

Induction of macrophage nitric oxide production by interferon‐γ and tumor necrosis factor‐α is enhanced by interleukin‐10

1993 • 83 citations

In vitro priming of tumor-reactive cytolytic T lymphocytes by combining IL-10 with B7-CD28 costimulation.

1995 • 70 citations

Identification and characterization of a new gene family induced during macrophage activation.

1991 • 54 citations

IL-10 inhibition of human prostate PC-3 ML cell metastases in SCID mice: IL-10 stimulation of TIMP-1 and inhibition of MMP-2/MMP-9 expression.

1997 • 45 citations

Differential responsiveness of human bronchial epithelial cells, lung carcinoma cells, and bronchial fibroblasts to interferon-gamma in vitro.

1994 • 40 citations

Interleukin-10 gene transfer inhibits murine mammary tumors and elevates nitric oxide

1998 • 38 citations

Promoter analysis of an interferon-inducible gene associated with macrophage activation.

1994 • 36 citations

Differential Effects of Pentoxifylline and Interleukin–10 on Production of Tumor Necrosis Factor and Inducible Nitric Oxide Synthase by Murine Macrophages

1997 • 26 citations

Opposing Effects of Interleukin‐10 on Mouse Macrophage Functions

1995 • 24 citations

Differential utilization of IFN-gamma-responsive elements in two maturationally distinct macrophage cell lines.

1995 • 23 citations