Non-stimulant treatments for ADHD

Adult Outcome of Hyperactive Boys

1993 • 1,373 citations

Diagnosis and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents

1998 • 1,095 citations

Clinical Relevance of the Primary Findings of the MTA: Success Rates Based on Severity of ADHD and ODD Symptoms at the End of Treatment

2001 • 1,066 citations

Hyperactive Boys Almost Grown Up

1985 • 996 citations

Pharmacological profile of antidepressants and related compounds at human monoamine transporters

1997 • 906 citations

Pharmacotherapy of Attention-Deficit Hyperactivity Disorder across the Life Cycle

1996 • 846 citations

Selective effects of methylphenidate in attention deficit hyperactivity disorder: A functional magnetic resonance study

1998 • 844 citations

Further Evidence for Family-Genetic Risk Factors in Attention Deficit Hyperactivity Disorder

1992 • 772 citations

Psychiatric Status of Hyperactives as Adults: A Controlled Prospective 15-Year Follow-up of 63 Hyperactive Children

1985 • 770 citations

Dopamine D4 receptor gene polymorphism is associated with attention deficit hyperactivity disorder.

1996 • 684 citations

Atomoxetine in the Treatment of Children and Adolescents With Attention-Deficit/Hyperactivity Disorder: A Randomized, Placebo-Controlled, Dose-Response Study

2001 • 661 citations

Effects of Methylphenidate on Extracellular Dopamine, Serotonin, and Norepinephrine: Comparison with Amphetamine

1997 • 613 citations

A Placebo-Controlled Study of Guanfacine in the Treatment of Children With Tic Disorders and Attention Deficit Hyperactivity Disorder

2001 • 564 citations

Hyperactive Boys Almost Grown Up

1991 • 559 citations

A REVIEW OF STIMULANT DRUG RESEARCH WITH HYPERACTIVE CHILDREN

1977 • 551 citations

ADHD Is Associated With Early Initiation of Cigarette Smoking in Children and Adolescents

1997 • 515 citations

Family-Genetic and Psychosocial Risk Factors in DSM-III Attention Deficit Disorder

1990 • 485 citations

Effects of acute subcutaneous nicotine on attention, information processing and short-term memory in alzheimer's disease

1992 • 478 citations

Family-Environment Risk Factors for Attention-Deficit Hyperactivity Disorder

1995 • 474 citations

Is maternal smoking during pregnancy a risk factor for attention deficit hyperactivity disorder in children?

1996 • 422 citations

Nicotine effects on adults with attention-deficit/hyperactivity disorder

1996 • 415 citations

A Twin Study of Hyperactivity—II. The Aetiological Role of Genes, Family Relationships and Perinatal Adversity

1989 • 370 citations

Assessing the abuse potential of methylphenidate in nonhuman and human subjects: a review

2001 • 357 citations

Cigarette smoking in adult patients diagnosed with attention deficit hyperactivity disorder

1995 • 345 citations

Bupropion Hydrochloride in Attention Deficit Disorder with Hyperactivity

1996 • 344 citations

A Double-Blind Placebo Controlled Study of Desipramine in the Treatment of ADD: I. Efficacy

1989 • 316 citations

Clonidine Benefits Children with Attention Deficit Disorder and Hyperactivity: Report of a Double-Blind Placebo-Crossover Therapeutic Trial

1985 • 315 citations

Differential Effects of Methylphenidate on Working Memory in ADHD Children with and without Comorbid Anxiety

1995 • 308 citations

An Open Trial of Guanfacine in the Treatment of Attention-Deficit Hyperactivity Disorder

1995 • 303 citations

Effect of Anxiety on Cognition, Behavior, and Stimulant Response in ADHD

1989 • 290 citations

Preferential stimulation of ventral tegmental area dopaminergic neurons by nicotine

1987 • 275 citations

Bupropion versus Methylphenidate in the Treatment of Attention-Deficit Hyperactivity Disorder

1995 • 256 citations

Guanfacine Treatment of Comorbid Attention-Deficit Hyperactivity Disorder and Tourette's Syndrome: Preliminary Clinical Experience

1995 • 250 citations

Imipramine and Methylphenidate Treatments of Hyperactive Boys

1974 • 244 citations

Dopamine D₄ Gene 7-Repeat Allele and Attention Deficit Hyperactivity Disorder

1999 • 243 citations

Controlled Stimulant Treatment of ADHD and Comorbid Tourette's Syndrome: Effects of Stimulant and Dose

1997 • 237 citations

Growth Deficits in ADHD Children Revisited: Evidence for Disorder-Associated Growth Delays?

1996 • 234 citations

Long-term Methylphenidate Therapy in Children With Comorbid Attention-Deficit Hyperactivity Disorder and Chronic Multiple Tic Disorder

1999 • 234 citations

Six-week, double-blind, placebo-controlled study of desipramine for adult attention deficit hyperactivity disorder

1996 • 234 citations

The Treatment of Attention-Deficit Hyperactivity Disorder in Tourette's Syndrome: A Double-Blind Placebo-Controlled Study With Clonidine and Desipramine

1995 • 229 citations

A Pilot Controlled Clinical Trial of ABT-418, a Cholinergic Agonist, in the Treatment of Adults With Attention Deficit Hyperactivity Disorder

1999 • 229 citations

Risperidone Treatment for Juvenile Bipolar Disorder: A Retrospective Chart Review

1999 • 226 citations

Which boys respond to stimulant medication? A controlled trial of methylphenidate in boys with disruptive behaviour

1987 • 211 citations

Cholinergic modulation of the content of temporal memory.

1987 • 210 citations

Time-Response Analysis of the Effect of Stimulant Medication on the Learning Ability of Children Referred for Hyperactivity

1978 • 210 citations

Pregnancy, delivery and infancy complications and attention deficit hyperactivity disorder: Issues of gene-environment interaction

1997 • 204 citations

A Pilot Study of Methyiphenidate, Clonidine, or the Combination in ADHD Comorbid with Aggressive Oppositional Defiant or Conduct Disorder

2000 • 203 citations

The Clinical Use of Stimulant Drugs in Children.

1972 • 184 citations

Efficacy of Methylphenidate for Attention-Deficit Hyperactivity Disorder in Children With Tic Disorder

1995 • 174 citations

Response of Children with ADHD to Methylphenidate: Interaction with Internalizing Symptoms

1994 • 165 citations

Cholinergic modulation of the content of temporal memory.

1987 • 161 citations

Bupropion Sustained Release in Adolescents With Comorbid Attention-Deficit/Hyperactivity Disorder and Depression

2001 • 161 citations

A Twin Study of Hyperactivity—I. An Examination of Hyperactivity Scores and Categories Derived from Rutter Teacher and Parent Questionnaires

1989 • 155 citations

Treatment of Hyperactive Children With Monoamine Oxidase Inhibitors

1985 • 148 citations

Bupropion treatment of attention-deficit hyperactivity disorder in adults

1990 • 145 citations

Segregation analysis of attention deficit hyperactivity disorder

1992 • 145 citations

Sudden Death in Children Treated with a Tricyclic Antidepressant

1991 • 143 citations

A Double-blind Placebo Controlled Study of Desipramine in the Treatment of ADD: II. Serum Drug Levels and Cardiovascular Findings

1989 • 141 citations

One-year follow-up of hyperactive boys treated with imipramine or methylphenidate

1975 • 141 citations

Do Typical Clinical Doses of Methylphenidate Cause Tics in Children Treated for Attention-Deficit Hyperactivity Disorder?

1999 • 131 citations

Clonidine in Child and Adolescent Psychiatry

1990 • 130 citations

Tricyclic Antidepressant and Methylphenidate Treatment of Attention Deficit Disorder in Children

1983 • 128 citations

An Open Trial of Bupropion for ADHD in Adolescents With Substance Use Disorders and Conduct Disorder

1998 • 128 citations

Venlafaxine in adults with attention-deficit/hyperactivity disorder: an open clinical trial.

1996 • 127 citations

Treatment of ADHD with fluoxetine: A preliminary trial

1991 • 123 citations

Epinephrine and Norepinephrine Act as Potent Agonists at the Recombinant Human Dopamine D4 Receptor

1997 • 121 citations

Guanfacine for Treatment of Attention-Deficit Hyperactivity Disorder in Boys

1995 • 118 citations

Effects of Imipramine and Dextroamphetamine on Behavior of Neuropsychiatrically Impaired Children

1972 • 112 citations

The effects of cigarettes of varying yield on rapid information processing performance

1984 • 112 citations

Nortriptyline Treatment of Children with Attention-deficit Hyperactivity Disorder and Tic Disorder or Tourette's Syndrome

1993 • 111 citations

Systematic Chart Review of the Pharmacologic Treatment of Comorbid Attention Deficit Hyperactivity Disorder in Youth with Bipolar Disorder

1999 • 108 citations

Growth Deficits in Children With Attention Deficit Hyperactivity Disorder

1998 • 106 citations

Cellular and Subcellular Localization of the Dopamine Transporter in Rat Cortex

1997 • 105 citations

Clonidine for Sleep Disturbances Associated with Attention-Deficit Hyperactivity Disorder

1994 • 104 citations

IMIPRAMINE AND METHYLPHENIDATE IN HYPERACTIVE CHILDREN

1980 • 104 citations

Release of dopamine and 5-hydroxytryptamine from rat striatal slices following activation of nicotinic cholinergic receptors

1983 • 102 citations

Attention, memory, and cigarette smoking

1984 • 102 citations

Estimation of the association between desipramine and the risk for sudden death in 5- to 14-year-old children.

1995 • 101 citations

Comparison of Clonidine Response in the Treatment of Attention-deficit Hyperactivity Disorder with and without Comorbid Tic Disorders

1993 • 97 citations

Combining Methylphenidate and Clonidine: A CLINICALLY SOUND MEDICATION OPTION

1999 • 96 citations

Is Attention Deficit Hyperactivity Disorder Familial?

1994 • 96 citations

Nicotine chewing gum (2 mg, 4 mg) and cigarette smoking: comparative effects upon vigilance and heart rate

1989 • 95 citations

Methylphenidate in Hyperactive Boys with Comorbid Tic Disorder: II. Short-Term Behavioral Effects in School Settings

1992 • 94 citations

A Controlled Study of Nortriptyline in Children and Adolescents with Attention Deficit Hyperactivity Disorder

2000 • 94 citations

Effects of prenatal nicotine exposure on rat striatal dopaminergic and nicotinic systems

1989 • 93 citations

Methylphenidate and Desipramine in Hospitalized Children: I. Separate and Combined Effects on Cognitive Function

1993 • 90 citations

Treatment effects of oral and transdermal clonidine in relation to methylphenidate: an open pilot study in ADD-H.

1987 • 87 citations

A Systematic Assessment of Tricyclic Antidepressants in the Treatment of Adult Attention-Deficit Hyperactivity Disorder

1995 • 87 citations

Pindolol and Methylphenidate in Children with Attention-Deficit Hyperactivity Disorder. Clinical Efficacy and Side-Effects

1996 • 86 citations

An open trial of venlafaxine in adult patients with attention deficit hyperactivity disorder.

1995 • 84 citations

Effects of buspirone and its metabolite, 1-(2-pyrimidinyl)piperazine, on brain monoamines and their metabolites in rats.

1989 • 84 citations

Long-Term Effects of Stimulant Medications on the Brain: Possible Relevance to the Treatment of Attention Deficit Hyperactivity Disorder

2001 • 81 citations

A double-blind trial of bupropion in children with attention deficit disorder.

1987 • 80 citations

Genetic Latent Structure Analysis of Dysmorphology in Attention Deficit Disorder

1990 • 76 citations

The Psychology of Separation and Loss

1988 • 75 citations

Open-label trial of venlafaxine in adults with attention deficit disorder.

1995 • 75 citations

Nortriptyline in the Treatment of ADHD: A Chart Review of 58 Cases

1993 • 73 citations

Dopamine Axons in Primate Prefrontal Cortex: Specificity of Distribution, Synaptic Targets, and Development

1997 • 70 citations

α2 ADRENERGIC AGONISTS

1998 • 69 citations

Effects of ?2-adrenoceptor agonists on locus coeruleus firing rate and brain noradrenaline turnover in N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ)-treated rats

1991 • 67 citations

AMITRIPTYLINE AND METHYLPHENIDATE TREATMENT OF BEHAVIORALLY DISORDERED CHILDREN

1977 • 66 citations

Desipramine in the Treatment of Children with Attention Deficit Disorder

1986 • 66 citations

Buspirone: chemical profile of a new class of anxioselective agents.

1982 • 66 citations

Carbamazepine Use in Children and Adolescents with Features of Attention-Deficit Hyperactivity Disorder: A Meta-Analysis

1996 • 64 citations

A Naturalistic Study of 24-Hour Electrocardiographic Recordings and Echocardiographic Findings in Children and Adolescents Treated with Desipramine

1993 • 62 citations

Desipramine Treatment of Boys with Attention-Deficit Hyperactivity Disorder and Tics: Preliminary Clinical Experience

1988 • 62 citations

Bupropion in children with attention deficit disorder.

1989 • 60 citations

Alcohol abuse and attention deficit disorder.

1983 • 59 citations

Behavioral effects of prenatal exposure to nicotine in guinea pigs.

1982 • 58 citations

A Double-blind Placebo Controlled Study of Desipramine in the Treatment of ADD: III. Lack of Impact of Comorbidity and Family History Factors on Clinical Response

1993 • 57 citations

Desipramine Treatment of Children with Attention-deficit Hyperactivity Disorder and Tic Disorder or Tourette's Syndrome

1993 • 57 citations

Long-Term Outcome in Attention-Deficit Hyperactivity Disorder

1992 • 51 citations

Increased AMPA receptor function in slices containing the prefrontal cortex of spontaneously hypertensive rats.

2001 • 51 citations

Propranolol for Adults with Temper Outbursts and Residual Attention Deficit Disorder

1986 • 50 citations

The Personality Inventory for Children and Response to Methylphenidate: Preliminary Evidence for Predictive Utility

1983 • 48 citations

A Pilot Study of Nadolol for Overt Aggression in Developmentally Delayed Individuals

1997 • 47 citations

Effects of methylphenidate on early adolescent growth

1990 • 46 citations

Postnatal behavioural effects of maternal nicotine exposure in rats

1988 • 44 citations

An Open Clinical Trial of Buspirone in Children With Attention‐Deficit/Hyperactivity Disorder

1998 • 43 citations

The use of imipramine in children's behavior disorders.

1970 • 41 citations

Selegiline in adults with attention deficit hyperactivity disorder: clinical efficacy and safety.

1996 • 40 citations

A case of Tourette's syndrome with symptoms of attention deficit disorder treated with desipramine.

1986 • 40 citations

Combination of Treatments for Attention Deficit Hyperactivity Disorder in Adults

1991 • 39 citations

Clinical Effects of Imipramine and Methylphenidate in Hyperactive Children

1975 • 38 citations

Motor Performance in Hyperactive Children Treated with Imipramine

1988 • 38 citations

Alterations in the vigilance performance of children receiving amitriptyline and methylphenidate pharmacotherapy

1976 • 38 citations

Comparison of guanfacine versus clonidine for efficacy, safety and occurrence of withdrawal syndrome in step-2 treatment of mild to moderate essential hypertension

1986 • 29 citations

Influence of repeated treatment with buspirone on central 5-hydroxytryptamine and dopamine synthesis

1992 • 28 citations

Imipramine in the Treatment of Minimal Brain Dysfunction in Children

1973 • 27 citations

The use of imipramine in Tourette's syndrome and attention deficit disorder: case report.

1985 • 25 citations

An indication for use of imipramine in attention deficit disorder

1982 • 24 citations

A Naturalistic Assessment of Protriptyline for Attention-Deficit Hyperactivity Disorder

1996 • 23 citations

Desipramine in the treatment of attention deficit disorder in adolescents.

1985 • 21 citations

Methylphenidate and Growth: Demonstration of a Growth Impairment and a Growth-Rebound Phenomenon

1986 • 20 citations

Case Series: Clonidine Has No Systematic Effects on PR or QTc Intervals in Children

1999 • 19 citations

Chronic administration of buspirone down-regulates 5-HT2 receptor binding sites

1991 • 17 citations

Genetic factors in hyperactivity.

1989 • 16 citations

Modification of hyperkinetic behavior by nortriptyline.

1973 • 9 citations

[Effectiveness and tolerance of the selective MAO-A inhibitor moclobemide in children with hyperkinetic syndrome].

1991 • 2 citations

Deleted Work

1955 • 0 citations