Hormonal regulation of extracellular plasminogen activators and Mr ∼ 54000 plasminogen activator inhibitor in human neoplastic cell lines, studied with monoclonal antibodies

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid

1956 • 14,202 citations

Plasminogen Activators, Tissue Degradation, and Cancer

1985 • 2,584 citations

Protein Inhibitors of Proteinases

1980 • 2,220 citations

Plasminogen: Purification from Human Plasma by Affinity Chromatography

1970 • 2,160 citations

HUMAN PLASMA PROTEINASE INHIBITORS

1983 • 2,129 citations

A better cell line for making hybridomas secreting specific antibodies

1978 • 1,649 citations

On the Regulation and Control of Fibrinolysis

1980 • 1,139 citations

A study of proteases and protease-inhibitor complexes in biological fluids

1978 • 810 citations

Proteinases in mammalian cells and tissues

1978 • 701 citations

Protein a from Staphylococcus aureus. Its isolation by affinity chromatography and its use as an immunosorbent for isolation of immunoglobulins

1972 • 607 citations

Concomitant secretion of prourokinase and of a plasminogen activator-specific inhibitor by cultured human monocytes-macrophages.

1984 • 418 citations

Demonstration of a fast-acting inhibitor of plasminogen activators in human plasma

1984 • 382 citations

Detection and partial characterization of an inhibitor of plasminogen activator in human platelets.

1984 • 365 citations

A proenzyme form of human urokinase.

1982 • 350 citations

Evidence for the Occurrence of a Fast-Acting Inhibitor for Tissue-Type Plasminogen Activator in Human Plasma

1984 • 345 citations

Demonstration of a fast-acting inhibitor of plasminogen activators in human plasma

1984 • 303 citations

Purification of zymogen to plasminogen activator from human glioblastoma cells by affinity chromatography with monoclonal antibody

1982 • 269 citations

Macrophage fibrinolytic activity: Identification of two pathways of plasmin formation by intact cells and of a plasminogen activator inhibitor

1982 • 225 citations

PROPERTIES OF PLASMINOGEN ACTIVATORS FORMED BY NEOPLASTIC HUMAN CELL CULTURES

1974 • 207 citations

Molecular species of plasminogen activators secreted by normal and neoplastic human cells.

1980 • 202 citations

Inactivation of tissue plasminogen activator in plasma. Demonstration of a complex with a new rapid inhibitor.

1984 • 193 citations

CULTURED GRANULOSA CELLS PRODUCE TWO PLASMINOGEN ACTIVATORS AND AN ANT IACTIVATOR, EACH REGULATED DIFFERENTLY BY GONADOTROPINS.

1985 • 181 citations

Immunocytochemical localization of urokinase-type plasminogen activator in Lewis lung carcinoma.

1984 • 173 citations

Reverse fibrin autography: A method to detect and partially characterize protease inhibitors after sodium dodecyl sulfate-polyacrylamide gel electrophoresis

1984 • 170 citations

Urokinase Inhibitor in Human Placenta

1968 • 167 citations

Molecular Basis of Biological Degradative Processes

1978 • 163 citations

Purification of a Specific Placental Plasminogen Activator Inhibitor by Monoclonal Antibody and Its Complex Formation with Plasminogen Activator

1985 • 161 citations

Human endothelial cells contain one type of plasminogen activator

1984 • 156 citations

Hormonal regulation of plasminogen activator mRNA production in porcine kidney cells

1983 • 151 citations

Purification of human fibroblast urokinase proenzyme and analysis of its regulation by proteases and protease nexin.

1984 • 134 citations

Isolation of tissue-type plasminogen activator-inhibitor complexes from human plasma

1984 • 132 citations

Urokinase‐type plasminogen activator and its inhibitor secreted by cultured human monocyte‐macrophages

1985 • 130 citations

Effects of the DNA intercalators 4'-(9-acridinylamino)methanesulfon-m-anisidide and 2-methyl-9-hydroxyellipticinium on topoisomerase II mediated DNA strand cleavage and strand passage

1985 • 127 citations

Human endothelial cells produce a plasminogen activator inhibitor and a tissue-type plasminogen activator-inhibitor complex

1984 • 118 citations

Plasminogen Activator Released as Inactive Proenzyme from Murine Cells Transformed by Sarcoma Virus

1982 • 111 citations

An inhibitor from placenta specifically binds urokinase and inhibits plasminogen activator released from ovarian carcinoma in tissue culture

1978 • 110 citations

An inhibitor of plasminogen activator in rabbit endothelial cells.

1981 • 108 citations

Inhibition of tissue-type plasminogen activator by conditioned medium from cultured human and porcine vascular endothelial cells

1983 • 99 citations

The dexamethasone-induced inhibitor of fibrinolytic activity in hepatoma cells. A cellular product which specifically inhibits plasminogen activation.

1982 • 95 citations

Serine enzymes released by cultured neoplastic cells.

1978 • 94 citations

Minactivin: A human monocyte product which specifically inactivates urokinase‐type plasminogen activators

1983 • 86 citations

Dexamethasone induction of an inhibitor of plasminogen activator in HTC hepatoma cells.

1984 • 84 citations

Proteolytic activation of tissue plasminogen activator by plasma and tissue enzymes

1984 • 79 citations

Inactive proenzyme to tissue-type plasminogen activator from human melanoma cells, identified after affinity purification with a monoclonal antibody.

1984 • 78 citations

Evidence for the presence of two different fibrinolytic inhibitors in human endothelial cell conditioned medium

1984 • 74 citations

Characteristics of interactions between surfactants and the human erythrocyte membrane

1971 • 74 citations

Induction of fibrinolytic activity in HeLa cells by phorbol myristate acetate. Tissue-type plasminogen activator antigen and mRNA augmentation require intermediate protein biosynthesis.

1985 • 73 citations

Plasminogen activator from cells transformed by an oncogenic virus. Inhibitors of the activation reaction

1979 • 72 citations

Hormonal regulation of plasminogen activator in rat hepatoma cells

1983 • 68 citations

Monoclonal antibody to human 66,000 molecular weight plasminogen activator from melanoma cells. Specific enzyme inhibition and one-step affinity purification.

1983 • 64 citations

HUMAN FIBROBLASTS PRODUCE INHIBITOR DIRECTED AGAINST PLASMINOGEN ACTIVATOR WHEN TREATED WITH GLUCOCORTICOIDS*

1981 • 62 citations

Tumor promoter PMA stimulates the synthesis and secretion of mouse pro-urokinase in MSV-transformed 3T3 cells: this is mediated by an increase in urokinase mRNA content.

1984 • 58 citations

Dexamethasone regulation of plasminogen activator in embryonic and tumor-derived human cells.

1980 • 54 citations

Effects of 12-O-Tetradecanoylphorbol 13-Acetate on the Production of mRNAs for Human Tissue-Type Plasminogen Activator

1983 • 53 citations

Proenzyme to urokinase‐type plasminogen activator in the mouse in vivo

1985 • 52 citations

Sequence of formation of molecular forms of plasminogen and plasmin-inhibitor complexes in plasma activated by urokinase or tissue-type plasminogen activator

1984 • 42 citations

Plasminogen activating enzyme in cultured glioblastoma cells. An immunofluorescence study with monoclonal antibody.

1982 • 41 citations

Plasminogen activator in psoriatic scales is of the tissue-type PA as identified by monoclonal antibodies

1985 • 32 citations

Transcriptional induction of urokinase in cultured human kidney carcinoma cells by tetradecanoyl‐phorbol‐acetate

1984 • 22 citations

Urokinase inhibitor in patients with bladder cancer

1974 • 17 citations

Hormonal regulation of protein synthesis in cultured kidney cells

1985 • 6 citations