Can soluble antigens induce CD8+ cytotoxic T-cell responses? A paradox revisited

New use of BCG for recombinant vaccines

1991 • 1,463 citations

Introduction of soluble protein into the class I pathway of antigen processing and presentation

1988 • 1,105 citations

Association of class I major histocompatibility heavy and light chains induced by viral peptides

1989 • 995 citations

Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay.

1976 • 951 citations

Cytotoxic T-Cell Immunity to Influenza

1983 • 932 citations

TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4−8+ T cells

1992 • 726 citations

In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine

1989 • 632 citations

Cytotoxic T Cells in Cytomegalovirus Infection

1982 • 610 citations

Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs

1990 • 479 citations

CD8-positive T lymphocytes specific for murine cytomegalovirus immediate-early antigens mediate protective immunity

1987 • 432 citations

Class I-restricted processing and presentation of exogenous cell-associated antigen in vivo.

1990 • 414 citations

Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter

1991 • 413 citations

Vaccinia Virus: A Tool for Research and Vaccine Development

1991 • 410 citations

Presentation of Exogenous Antigen with Class I Major Histocompatibility Complex Molecules

1990 • 338 citations

Humoral and cell-mediated immune responses to live recombinant BCG–HIV vaccines

1991 • 315 citations

Induction of cytotoxic T-cell responses in vivo in the absence of CD4 helper cells

1987 • 304 citations

Eradication of adenovirus E1-induced tumors by E1A-specific cytotoxic T lymphocytes

1989 • 300 citations

Ham-2 corrects the class I antigen-processing defect in RMA-S cells

1992 • 289 citations

Dendritic cells are accessory cells for the development of anti-trinitrophenyl cytotoxic T lymphocytes.

1980 • 265 citations

A cytotoxic T lymphocyte inhibits acquired immunodeficiency syndrome virus replication in peripheral blood lymphocytes.

1989 • 258 citations

Oral Salmonella typhimurium Vaccine Expressing Circumsporozoite Protein Protects Against Malaria

1988 • 250 citations

Saponin adjuvant enhancement of antigen-specific immune responses to an experimental HIV-1 vaccine.

1992 • 240 citations

The binary logic of antigen processing and presentation to T cells

1990 • 235 citations

Saponin adjuvant induction of ovalbumin-specific CD8+ cytotoxic T lymphocyte responses.

1992 • 224 citations

Induction of ovalbumin-specific cytotoxic T cells by in vivo peptide immunization.

1989 • 220 citations

Class discrimination in the world of immunology

1987 • 214 citations

Characterization of antigen-presenting cells that present exogenous antigens in association with class I MHC molecules.

1993 • 206 citations

HIV-1 gag-specific cytotoxic T lymphocytes recognize multiple highly conserved epitopes. Fine specificity of the gag-specific response defined by using unstimulated peripheral blood mononuclear cells and cloned effector cells.

1991 • 191 citations

Soluble proteins delivered to dendritic cells via pH-sensitive liposomes induce primary cytotoxic T lymphocyte responses in vitro.

1992 • 185 citations

Cytotoxic T lymphocytes against a soluble protein

1987 • 178 citations

Immune-stimulating complexes containing Quil A and protein antigen prime class I MHC-restricted T lymphocytes in vivo and are immunogenic by the oral route.

1991 • 174 citations

Antigen Presentation Requires Transport of MHC Class I Molecules from the Endoplasmic Reticulum

1990 • 167 citations

Analyses of the cytotoxic T lymphocyte responses to glycoprotein and nucleoprotein components of lymphocytic choriomeningitis virus

1988 • 155 citations

Macrophages as accessory cells for class I MHC-restricted immune responses.

1991 • 148 citations

Measles virus transmembrane fusion protein synthesized de novo or presented in immunostimulating complexes is endogenously processed for HLA class I- and class II-restricted cytotoxic T cell recognition.

1992 • 131 citations

Induction of a cellular immune response to a foreign antigen by a recombinant Listeria monocytogenes vaccine.

1992 • 116 citations

pH sensitive liposomes provide an efficient means of sensitizing target cells to class I restricted CTL recognition of a soluble protein

1991 • 114 citations

Biology of simian virus 40 (SV40) transplantation antigen (TrAg)

1980 • 99 citations

Vaccination of class I major histocompatibility complex (MHC)-restricted murine CD8+ cytotoxic T lymphocytes towards soluble antigens: immunostimulating-ovalbumin complexes enter the class I MHC-restricted antigen pathway and allow sensitization against the immunodominant peptide

1991 • 97 citations

Intracellular traffic and antigen processing

1989 • 92 citations

Specificity of cytotoxicity T cells directed to influenza virus hemagglutinin.

1979 • 61 citations

Bone marrow macrophages process exogenous Toxoplasma gondii polypeptides for recognition by parasite-specific cytolytic T lymphocytes.

1993 • 60 citations

Antigenic specificity of the cytolytic T lymphocyte (CTL) response to murine sarcoma virus-induced tumors. II. Analysis of the clonal progeny of CTL precursors stimulated in vitro with syngeneic tumor cells.

1980 • 54 citations

Functional activity in vivo of effector T cell populations. II. Anti-tumor activity exhibited by syngeneic anti-MoMULV-specific cytolytic T cell clones.

1984 • 53 citations

Influenza virus hemagglutinin-specific cytotoxic T cell response induced by polypeptide produced in Escherichia coli.

1985 • 51 citations

Induction of Influenza A Virus Cross-reactive Cytotoxic T Cells by a Nucleoprotein/Haemagglutinin Preparation

1985 • 50 citations

Enhancement of tumor growth correlates with suppression of the tumor-specific cytolytic T lymphocyte response in mice chronically infected by Trypanosoma cruzi.

1985 • 37 citations

Requirement of Histocompatible Macrophages for the Induction of a Secondary Cytotoxic Response to Syngeneic Tumor Cells in vitro

1979 • 28 citations

Accessory Cell Requirements for the Generation of Cytolytic T Lymphocytes

1979 • 28 citations

Accessory cells in the in vitro generation of type C viruses specific T killer lymphocytes. I. Role of macrophages in primary anti-FMR reaction.

1981 • 14 citations

Deleted Work

1955 • 0 citations