New use of BCG for recombinant vaccines

Phagosome-lysosome interactions in cultured macrophages infected with virulent tubercle bacilli. Reversal of the usual nonfusion pattern and observations on bacterial survival.

1975 • 528 citations

Stress Proteins and Immunology

1990 • 458 citations

Stress proteins are immune targets in leprosy and tuberculosis.

1988 • 446 citations

Induction of Salmonella Stress Proteins Upon Infection of Macrophages

1990 • 429 citations

Class I-restricted processing and presentation of exogenous cell-associated antigen in vivo.

1990 • 414 citations

Site-specific integration of mycobacteriophage L5: integration-proficient vectors for Mycobacterium smegmatis, Mycobacterium tuberculosis, and bacille Calmette-Guérin.

1991 • 397 citations

CD8+ T lymphocytes in intracellular microbial infections

1988 • 335 citations

Lysogeny and transformation in mycobacteria: stable expression of foreign genes.

1988 • 321 citations

Introduction of foreign DNA into mycobacteria using a shuttle phasmid

1987 • 312 citations

Impaired resistance to Mycobacterium tuberculosis infection after selective in vivo depletion of L3T4+ and Lyt-2+ T cells

1987 • 287 citations

Characterization, sequence determination, and immunogenicity of a 64-kilodalton protein of Mycobacterium bovis BCG expressed in escherichia coli K-12

1987 • 252 citations

Quality control of BCG vaccine by WHO: a review of factors that may influence vaccine effectiveness and safety.

1990 • 239 citations

Differential stringent control of the tandem E. coli ribosomal RNA promoters from the rrnA operon expressed in vivo in multicopy plasmids

1983 • 202 citations

Functional analysis of influenza-specific helper T cell clones in vivo. T cells specific for internal viral proteins provide cognate help for B cell responses to hemagglutinin.

1986 • 199 citations

A heat shock operon in Coxiella burnetti produces a major antigen homologous to a protein in both mycobacteria and Escherichia coli

1988 • 198 citations

Mycobacteria‐reactive Lyt‐2⁺ T cell lines

1988 • 175 citations

IMMUNOTHERAPY VERSUS CHEMOTHERAPY IN LOCALISED CUTANEOUS LEISHMANIASIS

1987 • 173 citations

Vaccines for the Third World

1989 • 136 citations

T cells primed by influenza virion internal components can cooperate in the antibody response to haemagglutinin

1979 • 125 citations

An immunodominant class I-restricted cytotoxic T lymphocyte determinant of human immunodeficiency virus type 1 induces CD4 class II-restricted help for itself.

1990 • 110 citations

La vaccination preventive contre la tuberculose par le "BCG"

1927 • 107 citations

Cloning and sequence of the gene for heat shock protein 60 from Chlamydia trachomatis and immunological reactivity of the protein

1991 • 106 citations

Complete nucleotide sequence of pAL5OOO, a plasmid from Mycobacterium fortuitum

1988 • 99 citations

A sensitive immunochemical assay for biologically active MuIFN-γ

1987 • 79 citations

In vitro influenza virus-specific antibody production in man: antigen-specific and HLA-restricted induction of helper activity mediated by cloned human T lymphocytes.

1982 • 75 citations

Molecular cloning and sequence analysis of the Sta58 major antigen gene of Rickettsia tsutsugamushi: sequence homology and antigenic comparison of Sta58 to the 60-kilodalton family of stress proteins

1990 • 62 citations

Strain Virulence and the Lysosomal Response in Macrophages Infected with Mycobacterium tuberculosis

1974 • 60 citations

Protein-specific cytotoxic T lymphocytes. Recognition of transfectants expressing intracellular, membrane-associated or secreted forms of β-galactosidase

1989 • 59 citations

Cloning and expression of functional fragment C of tetanus toxin

1990 • 58 citations

Immunology and Immunopathology of the Intestines: Recombinant Avirulent Salmonella Vaccine Strains with Stable Maintenance and High Level Expression of Cloned Genes in Vivo

1989 • 55 citations

Biomedical science and the Third World: under the volcano.

1989 • 18 citations

Trypanothione Reductase

1989 • 15 citations