Genetically mediated brain abnormalities in schizophrenia

Effect of COMT Val ^108/158 Met genotype on frontal lobe function and risk for schizophrenia

2001 • 2,408 citations

Serotonin Transporter Genetic Variation and the Response of the Human Amygdala

2002 • 2,332 citations

A review of MRI findings in schizophrenia

2001 • 2,310 citations

The neuropathology of schizophrenia

1999 • 1,664 citations

The reduced neuropil hypothesis: a circuit based model of schizophrenia

1999 • 918 citations

Abnormally High Neuronal Density in the Schizophrenic Cortex

1995 • 866 citations

Physiological Dysfunction of the Dorsolateral Prefrontal Cortex in Schizophrenia Revisited

2000 • 811 citations

Prefrontal neurons and the genetics of schizophrenia

2001 • 738 citations

MRI anatomy of schizophrenia

1999 • 735 citations

Impaired Attention, Genetics, and the Pathophysiology of Schizophrenia

1994 • 671 citations

Evidence of dysfunction of a prefrontal-limbic network in schizophrenia: a magnetic resonance imaging and regional cerebral blood flow study of discordant monozygotic twins

1992 • 665 citations

The roles of prefrontal brain regions in components of working memory: Effects of memory load and individual differences

1999 • 549 citations

Schizophrenia susceptibility loci on chromosomes 13q32 and 8p21

1998 • 542 citations

Reduced frontotemporal functional connectivity in schizophrenia associated with auditory hallucinations

2002 • 534 citations

Genetics of bipolar disorder

1999 • 529 citations

Location of a Major Susceptibility Locus for Familial Schizophrenia on Chromosome 1q21-q22

2000 • 528 citations

Schizophrenic subjects show aberrant fMRI activation of dorsolateral prefrontal cortex and basal ganglia during working memory performance

2000 • 498 citations

Impaired recruitment of the hippocampus during conscious recollection in schizophrenia

1998 • 493 citations

Structural Abnormalities in Frontal, Temporal, and Limbic Regions and Interconnecting White Matter Tracts in Schizophrenic Patients With Prominent Negative Symptoms

2001 • 454 citations

Functional Hypofrontality and Working Memory Dysfunction in Schizophrenia

1998 • 403 citations

Genomewide Genetic Linkage Analysis Confirms the Presence of Susceptibility Loci for Schizophrenia, on Chromosomes 1q32.2, 5q33.2, and 8p21-22 and Provides Support for Linkage to Schizophrenia, on Chromosomes 11q23.3-24 and 20q12.1-11.23

2001 • 376 citations

Magnetic resonance imaging of brain in people at high risk of developing schizophrenia

1999 • 362 citations

Brain-derived neurotrophic factor and neurotrophin 3 in schizophrenic psychoses

2001 • 355 citations

Abnormal expression of brain-derived neurotrophic factor and its receptor in the corticolimbic system of schizophrenic patients

2000 • 340 citations

Abnormal monitoring of inner speech: a physiological basis for auditory hallucinations

1995 • 340 citations

Association of codon 108/158 catechol-O-methyltransferase gene polymorphism with the psychiatric manifestations of velo-cardio-facial syndrome

1996 • 308 citations

Neuropsychological Risk Indicators for Schizophrenia: A Review of Family Studies

1994 • 303 citations

Genome scan of European-American schizophrenia pedigrees: Results of the NIMH genetics initiative and millennium consortium

1998 • 278 citations

Brain structure, genetic liability, and psychotic symptoms in subjects at high risk of developing schizophrenia

2001 • 274 citations

The dysplastic net hypothesis: an integration of developmental and dysconnectivity theories of schizophrenia

1997 • 273 citations

Left Hippocampal Volume as a Vulnerability Indicator for Schizophrenia

2002 • 264 citations

Corticosterone Effects on BDNF Expression in the Hippocampus Implications for Memory Formation

2000 • 263 citations

Nicotinic Receptor Function in Schizophrenia

1996 • 261 citations

Fetal Hypoxia and Structural Brain Abnormalities in Schizophrenic Patients, Their Siblings, and Controls

2002 • 260 citations

Regional Gray Matter, White Matter, and Cerebrospinal Fluid Distributions in Schizophrenic Patients, Their Siblings, and Controls

1998 • 252 citations

Thalamic and amygdala–hippocampal volume reductions in first-degree relatives of patients with schizophrenia: an MRI-based morphometric analysis

1999 • 248 citations

Structural Brain Abnormalities in Patients With Schizophrenia and Their Healthy Siblings

2000 • 229 citations

Contributions of Genetic Risk and Fetal Hypoxia to Hippocampal Volume in Patients With Schizophrenia or Schizoaffective Disorder, Their Unaffected Siblings, and Healthy Unrelated Volunteers

2002 • 226 citations

Volume Changes in Gray Matter in Patients With Schizophrenia

2002 • 212 citations

An In Vivo Study of the Prefrontal Cortex of Schizophrenic Patients at Different Stages of Illness via Phosphorus Magnetic Resonance Spectroscopy

1995 • 203 citations

Multicenter Linkage Study of Schizophrenia Candidate Regions on Chromosomes 5q, 6q, 10p, and 13q: Schizophrenia Linkage Collaborative Group III

2000 • 203 citations

Cortical Dysfunction in Schizophrenia During Auditory Word and Tone Working Memory Demonstrated by Functional Magnetic Resonance Imaging

1998 • 194 citations

Functional anatomy of verbal fluency in people with schizophrenia and those at genetic risk

2000 • 194 citations

Association between the functional variant of the catechol-O-methyltransferase (COMT) gene and type 1 alcoholism

1999 • 191 citations

Linkage disequilibrium for schizophrenia at the chromosome 15q13-14 locus of the ?7-nicotinic acetylcholine receptor subunit gene (CHRNA7)

2001 • 185 citations

Insular cortex abnormalities in schizophrenia: a structural magnetic resonance imaging study of first-episode patients

2000 • 184 citations

Cortical and Subcortical Gray Matter Abnormalities in Schizophrenia Determined Through Structural Magnetic Resonance Imaging With Optimized Volumetric Voxel-Based Morphometry

2002 • 180 citations

Psychometric High-risk Paradigm, Perceptual Aberrations, and Schizotypy: An Update

1994 • 176 citations

Brain Derived Neurotrophic Factor (BDNF) gene variants association with age at onset and therapeutic response in schizophrenia

2000 • 175 citations

A genome-wide autosomal screen for schizophrenia susceptibility loci in 71 families with affected siblings: support for loci on chromosome 10p and 6

2000 • 172 citations

Brain-derived neurotrophic factor and tyrosine kinase receptor TrkB in rat brain are significantly altered after haloperidol and risperidone administration

2000 • 170 citations

The neurobiology of social recognition, approach, and avoidance

2002 • 169 citations

Eye Tracking and Schizophrenia: A Selective Review

1994 • 164 citations

Partial Volume Decrease of the Thalamus in Relatives of Patients With Schizophrenia

1998 • 159 citations

The effect of treatment with antipsychotic drugs on brain N-acetylaspartate measures in patients with schizophrenia

2001 • 156 citations

Quetiapine attenuates the immobilization stress-induced decrease of brain-derived neurotrophic factor expression in rat hippocampus

2002 • 154 citations

Magnetic resonance imaging and spectroscopy in offspring at risk for schizophrenia: Preliminary studies

1997 • 145 citations

Modality specific neural correlates of auditory and somatic hallucinations

2001 • 145 citations

Backward Masking Performance in Unaffected Siblings of Schizophrenic Patients

1997 • 144 citations

Hippocampal N-acetyl aspartate in unaffected siblings of patients with schizophrenia: a possible intermediate neurobiological phenotype

1998 • 137 citations

Evoked cerebral potential correlates of C-fibre activity in man

1983 • 136 citations

A functional serotonin transporter (5-HTT) polymorphism is associated with psychosis in neuroleptic-free schizophrenics

1998 • 131 citations

Genes, Experience, and Chance in Schizophrenia--Positioning for the 21st Century

1997 • 128 citations

"Schizotaxia": Clinical Implications and New Directions for Research

2001 • 118 citations

Suicidal behavior in patients with schizophrenia is related to COMT polymorphism

2000 • 114 citations

Schizophrenia: A Review of Genetic Studies

1999 • 114 citations

Higher scores of self reported schizotypy in healthy young males carrying the COMT high activity allele

2002 • 113 citations

Attenuated frontal activation in schizophrenia may be task dependent

1999 • 112 citations

Amygdala–hippocampal volume and verbal memory in first-degree relatives of schizophrenic patients

2001 • 108 citations

Proton Magnetic Resonance Spectroscopy in the Frontal and Temporal Lobes of Neuroleptic Naive Patients with Schizophrenia

1999 • 104 citations

A Turning Point in Schizophrenia Genetics

1997 • 101 citations

Brain changes in schizophrenia

1998 • 99 citations

The Maudsley Family Study 4. Normal planum temporale asymmetry in familial schizophrenia

1997 • 96 citations

Changes in Levels of Phosphorus Metabolites in Temporal Lobes of Drug-Naive Schizophrenic Patients

1999 • 96 citations

Excessive recruitment of neural systems subserving logical reasoning in schizophrenia

2002 • 95 citations

Association study of a functional catechol-O-methyltransferase gene polymorphism in Japanese schizophrenics

1998 • 94 citations

Schizophrenia and functional polymorphisms in the MAOA and COMT genes: No evidence for association or epistasis

2002 • 92 citations

Left striato-pallidal hyperactivity in schizophrenia. Part II: Phenomenology and thought disorder.

1989 • 88 citations

Evidence for linkage disequilibrium between the alpha 7‐nicotinic receptor gene (CHRNA7) locus and schizophrenia in Azorean families*

2001 • 87 citations

Treatment of nonpsychotic relatives of patients with schizophrenia: four case studies

1999 • 87 citations

Neural Correlates of Eye Tracking Deficits in First-degree Relatives of Schizophrenic Patients

1999 • 74 citations

Genetic Transmission of Negative and Positive Symptoms in the Biological Relatives of Schizophrenics

1991 • 71 citations

Lateralized abnormality of high-energy phosphate and bilateral reduction of phosphomonoester measured by phosphorus-31 magnetic resonance spectroscopy of the frontal lobes in schizophrenia

1995 • 69 citations

Modulation of DOI-induced increases in cortical BDNF expression by group II mGlu receptors

2002 • 67 citations

Structural MRI of the brain in presumed carriers of genes for schizophrenia, their affected and unaffected siblings.

2002 • 67 citations

Altered cerebral perfusion measured by SPECT in relatives of patients with schizophrenia

1999 • 63 citations

Potential linkage disequilibrium between schizophrenia and locus D22S278 on the long arm of chromosome 22

1995 • 58 citations

Use of a neurophysiological trait in linkage analysis of schizophrenia

1993 • 58 citations

Schizophrenia: A Review of Genetic Studies

1999 • 57 citations

Cerebral Phosphate Metabolism in First-Degree Relatives of Patients With Schizophrenia

2001 • 51 citations

Genetics of bipolar affective disorder

2000 • 49 citations

Reduced N-Acetylaspartate in Prefrontal Cortex of Adult Rats with Neonatal Hippocampal Damage

2002 • 46 citations

Proton Magnetic Resonance Spectroscopy of the Human Brain in Schizophrenia

2000 • 43 citations

A magnetic resonance imaging study of corpus callosum size in familial schizophrenic subjects,their relatives, and normal controls

2000 • 38 citations

Human Leukocyte Antigen and Season of Birth in Japanese Patients With Schizophrenia

2000 • 37 citations

Association of ZNF74 gene genotypes with age-at-onset of schizophrenia

2001 • 33 citations

Subtype-associated metabolite differences in the temporal lobe in schizophrenia detected by proton magnetic resonance spectroscopy

1999 • 32 citations

セロトニントランスポーター遺伝子型とヒト扁桃体反応, Hariri AR, Mattay VS, Tessitore A, et al, Serotonin transporter genetic variation and the response of the human amygdata, Science 297, 400-403, 2002

2003 • 26 citations

The Human Genome: Mutations

2002 • 20 citations

Heritability Heightens Brain Metabolite Differences in Schizophrenia

2000 • 18 citations

Cerebral Phosphate Metabolism in First-Degree Relatives of Patients With Schizophrenia

2001 • 5 citations

[Genetic analysis of anatomical and morphologic traits of the brain, determined by magnetic resonance imaging in families of schizophrenic patients].

1999 • 5 citations

[Rigidity of psyche processes and factors predisposing to schizophrenia].

2002 • 1 citations