Sequences of human immunoglobulin switch regions: implications for recombination and transcription

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

1987 • 1,936 citations

A rapid single-stranded cloning strategy for producing a sequential series of overlapping clones for use in DNA sequencing: Application to sequencing the corn mitochondrial 18 S rDNA

1985 • 1,051 citations

Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control.

1988 • 583 citations

α-Interferon-induced transcription of HLA and metallothionein genes containing homologous upstream sequences

1985 • 498 citations

Arrangement of human immunoglobulin heavy chain constant region genes implies evolutionary duplication of a segment containing γ, ε and α genes

1982 • 421 citations

Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE production.

1990 • 353 citations

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching.

1986 • 344 citations

Recombination-stimulating sequences in yeast ribosomal DNA correspond to sequences regulating transcription by RNA polymerase I

1987 • 317 citations

A convenient and adaptable package of computer programs for DNA and protein sequence management, analysis and homology determination

1984 • 285 citations

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes.

1988 • 285 citations

Molecular cloning and characterization of a human DNA binding factor that represses transcription

1989 • 285 citations

Mitogen- and IL-4-regulated expression of germ-line Ig γ2b transcripts: Evidence for directed heavy chain class switching

1988 • 277 citations

A single DNA response element can confer inducibility by both alpha- and gamma-interferons.

1989 • 262 citations

Homology requirements for recombination in Escherichia coli.

1985 • 255 citations

Repression of the IgH Enhancer in Teratocarcinoma Cells Associated with a Novel Octamer Factor

1989 • 176 citations

Switch region of immunoglobulin Cμ gene is composed of simple tandem repetitive sequences

1981 • 173 citations

IgE secretion by Epstein-Barr virus-infected purified human B lymphocytes is stimulated by interleukin 4 and suppressed by interferon gamma.

1989 • 167 citations

Interactions of alpha- and gamma-interferon in the transcriptional regulation of the gene encoding a guanylate-binding protein.

1989 • 159 citations

A multiple sequence alignment program

1986 • 158 citations

Nucleotide sequences of switch regions of immunoglobulin C epsilon and C gamma genes and their comparison.

1982 • 157 citations

Duplication and deletion in the human immunoglobulin ϵ genes

1982 • 146 citations

MECHANISM AND DEVELOPMENTAL PROGRAM OF IMMUNOGLOBULIN GENE REARRANGEMENT IN MAMMALS

1989 • 144 citations

Interferon-responsive regulatory elements in the promoter of the human 2',5'-oligo(A) synthetase gene.

1987 • 137 citations

Structure and expression of germ line immunoglobulin gamma 2b transcripts.

1988 • 136 citations

Rapid induction of transcription of unrearranged S gamma 1 switch regions in activated murine B cells by interleukin 4.

1989 • 134 citations

Overlapping sites for constitutive and induced DNA binding factors involved in interferon-stimulated transcription.

1989 • 134 citations

A gamma-interferon-induced factor that binds the interferon response sequence of the MHC class I gene, H-2Kb.

1989 • 113 citations

Immunoglobulin gene organisation and expression in haemopoietic stem cell leukaemia.

1983 • 112 citations

Structure and expression of germ line immunoglobulin heavy-chain epsilon transcripts: interleukin-4 plus lipopolysaccharide-directed switching to C epsilon.

1990 • 111 citations

DNase I hypersensitive sites in the chromatin of human μ immunoglobulin heavy-chain genes

1983 • 110 citations

Complete physical map of the human immunoglobulin heavy chain constant region gene complex.

1989 • 109 citations

Involvement of Double-strand Chromosomal Breaks for Mating-type Switching in Saccharomyces cerevisiae

1984 • 98 citations

Evolutionary approach to the question of immunoglobulin heavy chain switching: evidence from cloned human and mouse genes.

1980 • 97 citations

Molecular aspects of heavy-chain class switching.

1989 • 95 citations

Nucleotide Sequence of a Human Immunoglobulin Cγ4 Gene

1981 • 91 citations

High-affinity binding site for a specific nuclear protein in the human IgM gene

1985 • 89 citations

DNA sequence of the murine gamma 1 switch segment reveals novel structural elements.

1986 • 86 citations

A model for the molecular requirements of immunoglobulin heavy chain class switching

1982 • 85 citations

A DNA Binding Protein Regulated by IL-4 and by Differentiation in B Cells

1988 • 79 citations

Effect of limited homology on gene conversion in a Saccharomyces cerevisiae plasmid recombination system.

1988 • 78 citations

Production of sterile transcripts of C_γ genes in an IgM-producing human neoplastic B cell line that switches to IgG-producing cells

1989 • 74 citations

Structure and expression of murine germ-line immunoglobulin epsilon heavy chain transcripts induced by interleukin 4.

1990 • 72 citations

A pattern of partially homologous recombination in mouse L cells.

1984 • 68 citations

Long terminal repeat-like elements flank a human immunoglobulin epsilon pseudogene that lacks introns.

1982 • 55 citations

Structure of germ line immunoglobulin alpha heavy-chain RNA and its location on polysomes.

1990 • 51 citations

Structure of the human immunoglobulin C epsilon 2 gene, a truncated pseudogene: implications for its evolutionary origin.

1983 • 51 citations

The human immunoglobulin C_μ–C_δlocus: complete nucleotide sequence and structural analysis

1989 • 45 citations

Immunoglobulin D switching can occur through homologous recombination in human B cells.

1990 • 45 citations

Identification of a nuclear factor that binds to a conserved sequence of the I-A beta gene.

1988 • 43 citations

Structure and Expression of Germ Line Immunoglobulin γ2b Transcripts

1988 • 36 citations

Structure and Expression of Germ Line Immunoglobulin Heavy-Chain ε Transcripts: Interleukin-4 Plus Lipopolysaccharide-Directed Switching to Cε

1990 • 33 citations

Sigma region located between C, and C, genes of human immunoglobulin heavy chain: possible involvement of tRNA-like structure in RNA splicing

1988 • 22 citations

Effect of Limited Homology on Gene Conversion in a Saccharomyces cerevisiae Plasmid Recombination System

1988 • 20 citations

Structure of Germ Line Immunoglobulin α Heavy-Chain RNA and Its Location on Polysomes

1990 • 19 citations

Illegitimate recombination in the histone multigenic family generates circular DNAs in Drosophila embryos

1988 • 17 citations

Immunoglobulin D Switching Can Occur through Homologous Recombination in Human Β Cells

1990 • 14 citations