Structure and Expression of Germ Line Immunoglobulin Heavy-Chain ε Transcripts: Interleukin-4 Plus Lipopolysaccharide-Directed Switching to Cε

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Elevated recombination rates in transcriptionally active DNA

1989 • 1,666 citations

B cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells.

1986 • 797 citations

Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

1985 • 710 citations

B-Cell Stimulatory Factor-1/Interleukin 4

1987 • 602 citations

Evidence for Trans splicing in trypanosomes

1986 • 486 citations

Introduced T cell receptor variable region gene segments recombine in pre-B cells: Evidence that B and T cells use a common recombinase

1986 • 452 citations

T cell-derived B cell differentiation factor(s). Effect on the isotype switch of murine B cells.

1982 • 445 citations

Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y box.

1988 • 432 citations

IgG2a restriction of murine antibodies elicited by viral infections.

1987 • 429 citations

Serological, biochemical, and functional identity of B cell-stimulatory factor 1 and B cell differentiation factor for IgG1.

1985 • 410 citations

Suppression of in vivo polyclonal IgE responses by monoclonal antibody to the lymphokine B-cell stimulatory factor 1.

1986 • 355 citations

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching.

1986 • 344 citations

Organization of the constant-region gene family of the mouse immunoglobulin heavy chain

1982 • 323 citations

Recombination between immunoglobulin variable region gene segments is enhanced by transcription

1986 • 308 citations

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes.

1988 • 285 citations

Mitogen- and IL-4-regulated expression of germ-line Ig γ2b transcripts: Evidence for directed heavy chain class switching

1988 • 277 citations

Human N-myc is closely related in organization and nucleotide sequence to c-myc

1986 • 273 citations

Cμ-containing transcripts initiate heterogeneously within the IgH enhancer region and contain a novel 5′-nontranslatable exon

1985 • 232 citations

Pleiotropy and redundancy: T cell-derived lymphokines in the immune response

1989 • 228 citations

Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching.

1986 • 220 citations

Mitogen plus interleukin 4 induction of C epsilon transcripts in B lymphoid cells.

1988 • 208 citations

Immunoglobulin heavy-chain expression and class switching in a murine leukaemia cell line

1982 • 173 citations

The nucleotide sequence of the mouse immunoglobulin epsilon gene: comparison with the human epsilon gene sequence.

1982 • 108 citations

Mediators of Anaphylaxis and Inflammation

1982 • 99 citations

Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes.

1985 • 99 citations

Non-B right-handed DNA conformations of homopurine.homopyrimidine sequences in the murine immunoglobulin C alpha switch region.

1988 • 97 citations

Directed Ig class switch recombination in activated murine B cells.

1987 • 94 citations

A DNA Binding Protein Regulated by IL-4 and by Differentiation in B Cells

1988 • 79 citations

Cloning of human immunoglobulin epsilon chain genes: evidence for multiple C epsilon genes.

1982 • 70 citations

Deletion of Cmu genes in mouse B lymphocytes upon stimulation with LPS.

1983 • 60 citations

Structural studies of cell surface and secreted IgG in LPS-stimulated murine B cells

1983 • 40 citations

Constant-Region Genes of the Immunoglobulin Heavy Chain and the Molecular Mechanism of Class Switching

1989 • 35 citations