Organs from mice deleted for NRH:quinone oxidoreductase 2 are deprived of the melatonin binding site MT₃

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses

1994 • 1,099 citations

Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor.

1995 • 878 citations

Melatonin receptors: Localization, molecular pharmacology and physiological significance

1994 • 615 citations

Identification of the Melatonin-binding SiteMT 3 as the Quinone Reductase 2

2000 • 589 citations

Free-Running Activity Rhythms in the Rat: Entrainment by Melatonin

1983 • 552 citations

Evidence of melatonin synthesis by human lymphocytes and its physiological significance: possible role as intracrine, autocrine, and/or paracrine substance

2004 • 459 citations

Expression cloning of a high-affinity melatonin receptor from Xenopus dermal melanophores.

1994 • 434 citations

Melatonin: a novel protective agent against oxidative injury of the ischemic/reperfused heart

2003 • 320 citations

Dual Signaling of Human Mel1a Melatonin Receptors via Gi2, Gi3, and Gq/11 Proteins

1999 • 258 citations

New selective ligands of human cloned melatonin MT1 and MT2 receptors

2003 • 239 citations

High Melatonin Concentrations in Third Ventricular Cerebrospinal Fluid Are Not due to Galen Vein Blood Recirculating through the Choroid Plexus1

1999 • 218 citations

Comparative pharmacological studies of melatonin receptors: mt1, mt2 and mt3/qr2. tissue distribution of mt3/qr2 11Abbreviations: MCA-NAT, methoxy-carbonylamino-N-acetyltrypta- mine, 2-[125I]-I-MCA-NAT, 2-[125I]-iodomethoxy-carbonylamino-N-acetyltryptamine; 2-IbMT, 2-iodo-N-butanoyl-5-methoxytryptamine; 4-P-PDOT, 4-phenyl-2-propionamido-tetraline; DH97, N-pentanoyl-2-benzyltryptamine; S20760, 5-methoxy-N-cyclopropanoyl-tryptamine; S24635, N-[2-(5-carbamoylbenzofuran-3-yl)ethyl]-acetamide; …

2001 • 186 citations

Differential signaling of human Mel1a and Mel1b melatonin receptors through the cyclic guanosine 3′-5′-monophosphate pathway

1999 • 160 citations

Pharmacokinetics and oral bioavailability of exogenous melatonin in preclinical animal models and clinical implications

1997 • 158 citations

Ubiquitous melatonin-presence and effects in unicells, plants and animals

1996 • 156 citations

Melatonin madness

1995 • 146 citations

2-[¹²⁵I]Iodomelatonin Binding Sites in Hamster Brain Membranes: Pharmacological Characteristics and Regional Distribution*

1988 • 134 citations

Nucleotide and deduced amino acid sequence of a human cDNA (NQO2) corresponding to a second member of the NAD(P)H:quinone oxidoreductase gene family. Extensive polymorphism at the NQO2 gene locus on chromosome 6

1990 • 127 citations

Unexpected genetic and structural relationships of a long-forgotten flavoenzyme to NAD(P)H:quinone reductase (DT-diaphorase)

1997 • 121 citations

2-[125I]Iodo-5-methoxycarbonylamino-N-acetyltryptamine: a selective radioligand for the characterization of melatonin ML2 binding sites

1996 • 111 citations

Disruption of Dihydronicotinamide Riboside:Quinone Oxidoreductase 2 (NQO2) Leads to Myeloid Hyperplasia of Bone Marrow and Decreased Sensitivity to Menadione Toxicity

2002 • 109 citations

Human FAD-dependent NAD(P)H diaphorase

1980 • 83 citations

Pharmacological characterization of melatonin binding sites in Syrian hamster hypothalamus

1990 • 78 citations

Characterization of 2-[125I]iodomelatonin binding sites in Syrian hamster peripheral organs.

1999 • 78 citations

Melatonin, Its Receptors, and Relationships with Biological Rhythm Disorders

1997 • 77 citations

Melatonin rescues dopamine neurons from cell death in tissue culture models of oxidative stress

1997 • 77 citations

Melatonin Ameliorates Neurologic Damage and Neurophysiologic Deficits in Experimental Models of Stroke

2003 • 67 citations

Therapeutic Perspectives for Melatonin Agonists and Antagonists

2003 • 66 citations

Melatonin madness

1996 • 61 citations

H2O2 induced lipid peroxidation in rat brain homogenates is greatly reduced by melatonin

1995 • 53 citations

Molecular pharmacology of the ovine melatonin receptor: comparison with recombinant human MT1 and MT2 receptors

2003 • 40 citations

Synthesis of Nitroindole Derivatives with High Affinity and Selectivity for Melatoninergic Binding Sites MT₃

2002 • 38 citations

Kinetic and Docking Studies of the Interaction of Quinones with the Quinone Reductase Active Site

2003 • 28 citations