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Nucleotide and deduced amino acid sequence of a human cDNA (NQO2) corresponding to a second member of the NAD(P)H:quinone oxidoreductase gene family. Extensive polymorphism at the NQO2 gene locus on chromosome 6

Data up to Jan 2025

Published1990
Citations127
References39

Total Citations Per Year

Abstract

References (39)

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The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells.

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DT-diaphorase as a quinone reductase: A cellular control device against semiquinone and superoxide radical formation

1982 • 530 citations

Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes

1984 • 411 citations

Menadione-induced cytotoxicity is associated with protein thiol oxidation and alteration in intracellular Ca2+ homeostasis

1984 • 376 citations

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1979 • 293 citations

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1982 • 292 citations

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1985 • 233 citations

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1982 • 179 citations

Human dioxin-inducible cytosolic NAD(P)H:menadione oxidoreductase. cDNA sequence and localization of gene to chromosome 16.

1988 • 174 citations

Induction of NAD(P)H:quinone reductase in murine hepatoma cells by phenolic antioxidants, azo dyes, and other chemoprotectors: a model system for the study of anticarcinogens.

1986 • 153 citations

Generalised deficiency of cytochrome b5 reductase in congenital methaemoglobinaemia with mental retardation

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Induction of dna damage by menadione (2-methyl-1,4-naphthoquinone) in primary cultures of rat hepatocytes

1984 • 124 citations

Cloning of DNA complementary to rat liver NADPH-cytochrome c (P-450) oxidoreductase and cytochrome P-450b mRNAs. Evidence that phenobarbital augments transcription of specific genes.

1982 • 120 citations

Localization of human variable and constant region immunoglobulin heavy chain genes on subtelomeric band q32 of chromosome 14

1982 • 101 citations

Localization of the normal allele of T24 human bladder carcinoma oncogene to chromosome 11

1982 • 101 citations

Purification and characterization of two isofunctional forms of NAD(P)H: quinone reductase from mouse liver.

1986 • 85 citations

Human FAD-dependent NAD(P)H diaphorase

1980 • 83 citations

Biospecific adsorption of hepatic DT-diaphorase on immobilized dicoumarol

1981 • 82 citations

NAD(P)H:menadione oxidoreductase. Novel purification of enzyme cDNA and complete amino acid sequence, and gene regulation.

1986 • 82 citations

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An interpretation of human diaphorase isozymes in terms of three gene loci DIA1, DIA2 and DIA3

1977 • 33 citations

Distribution of newly synthesized DT-diaphorase in rat liver

1982 • 32 citations

Immunochemical studies on two DT diaphorase active antigens isolated from rat liver cytosol by affinity chromatography

1980 • 23 citations

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Nucleotide and deduced amino acid sequence of a human cDNA (NQO2) corresponding to a… (1990) – Biochemistry | Metascience Observatory Explorer