Development of Cell Lines Capable of Complementing E1, E4, and Protein IX Defective Adenovirus Type 5 Mutants

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

Manipulation of Adenovirus Vectors

2003 • 780 citations

An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.

1994 • 743 citations

A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5

1988 • 606 citations

Methods for construction of adenovirus vectors

1995 • 483 citations

Packaging capacity and stability of human adenovirus type 5 vectors

1993 • 457 citations

Poly(A) signals

1991 • 438 citations

Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff

1985 • 383 citations

Adenovirus as an expression vector in muscle cells in vivo.

1992 • 301 citations

Redundant control of adenovirus late gene expression by early region 4

1989 • 261 citations

Adenovirus early region 4 encodes two gene products with redundant effects in lytic infection

1989 • 225 citations

Emergence of Early Region 1-Containing Replication-Competent Adenovirus in Stocks of Replication-Defective Adenovirus Recombinants (ΔE1 + ΔE3) During Multiple Passages in 293 Cells

1994 • 193 citations

Expression of Heterologous Sequences in Adenoviral Vectors

1992 • 171 citations

Localization of the adenovirus early region 1B 55-kilodalton protein during lytic infection: association with nuclear viral inclusions requires the early region 4 34-kilodalton protein

1991 • 154 citations

Adenoviral early region 4 is required for efficient viral DNA replication and for late gene expression

1986 • 145 citations

A Recombinant Human Adenovirus Vaccine against Rabies

1990 • 145 citations

Interaction of adenoviral E4 and E1b products in late gene expression

1990 • 143 citations

A cell line that supports the growth of a defective early region 4 deletion mutant of human adenovirus type 2.

1983 • 141 citations

Monitoring foreign gene expression by a human adenovirus-based vector using the firefly luciferase gene as a reporter

1993 • 141 citations

Adenovirus type 5 virions can be assembled in vivo in the absence of detectable polypeptide IX

1981 • 137 citations

Mucosal Immunity and Protection after Intranasal Immunization with Recombinant Adenovirus Expressing Herpes Simplex Virus Glycoprotein B

1993 • 136 citations

A cascade of adenovirus early functions is required for expression of adeno-associated virus

1981 • 122 citations

Gene Therapy for Cystic Fibrosis Using E1-Deleted Adenovirus: A Phase I Trial in the Nasal Cavity. University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

1994 • 119 citations

[2] Techniques for human adenovirus vector construction and characterization

1995 • 118 citations

Development of a helper-independent human adenovirus vector and its use in the transfer of the herpes simplex virus thymidine kinase gene

1986 • 113 citations

mRNAs from human adenovirus 2 early region 4

1984 • 95 citations

Adenovirus early region 4 is essential for normal stability of late nuclear RNAs

1989 • 87 citations

Adenovirus-mediated transfer of a gene encoding human apolipoprotein A-I into normal mice increases circulating high-density lipoprotein cholesterol.

1994 • 86 citations

Characterization of the major mRNAs from adenovirus 2 early region 4 by cDNA cloning and sequencing

1984 • 69 citations

Splice junctions in adenovirus 2 early region 4 mRNAs: multiple splice sites produce 18 to 24 RNAs

1984 • 67 citations

Protective Immunity to Rotavirus-Induced Diarrhoea Is Passively Transferred to Newborn Mice from Naive Dams Vaccinated with a Single Dose of a Recombinant Adenovirus Expressing Rotavirus VP7sc

1993 • 65 citations

Highly inducible synthesis of heterologous proteins in epithelial cells carrying a glucocorticoid-responsive vector

1992 • 62 citations

Two Adenovirus Proteins with Redundant Activities in Virus Growth Facilitates Tripartite Leader mRNA Accumulation

1993 • 61 citations

Protection elicited by a replication-defective adenovirus vector expressing the tick-borne encephalitis virus non-structural glycoprotein NS1

1994 • 56 citations

Adenoviral-mediated gene transfer of human surfactant protein B to respiratory epithelial cells.

1994 • 54 citations

Mapping of a 14,000-dalton antigen to early region 4 of the human adenovirus 5 genome

1983 • 47 citations

Efficacy of adenovirus-vectored respiratory syncytial virus vaccines in a new ferret model

1994 • 46 citations

Expression of the Glycoprotein of Vesicular Stomatitis Virus by Infectious Adenovirus Vectors

1989 • 44 citations

[15] Use of fluorography for sensitive isotope detection in polyacrylamide gel electrophoresis and related techniques

1983 • 40 citations

Immunogenicity in mice of tandem repeats of an epitope from herpes simplex gD protein when expressed by recombinant adenovirus vectors

1993 • 38 citations

A block of transcription elongation by RNA polymerase II at synthetic sites in vitro

1989 • 37 citations

Investigation of promoter function in human and animal cells infected with human recombinant adenoviruses expressing rotavirus antigen VP7sc

1995 • 24 citations

Synthesis and Processing of the Haemagglutinin--esterase Glycoprotein of Bovine Coronavirus Encoded in the E3 Region of Adenovirus

1992 • 23 citations

Expression of the gene encoding secreted placental alkaline phosphatase (SEAP) by a nondefective adenovirus vector

1993 • 12 citations

Function and immunogenicity of human parainfluenza virus 3 glycoproteins expressed by recombinant adenoviruses

1992 • 12 citations

Expression of the OSU rotavirus outer capsid protein VP4 by an adenovirus recombinant

1992 • 11 citations