Fractionation and characterization of oligomeric, protofibrillar and fibrillar forms of β-amyloid peptide

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Maturation of the head of bacteriophage T4

1973 • 3,781 citations

Diffusible, nonfibrillar ligands derived from Aβ _1–42 are potent central nervous system neurotoxins

1998 • 3,404 citations

A constrained regularization method for inverting data represented by linear algebraic or integral equations

1982 • 2,616 citations

The molecular pathology of Alzheimer's disease

1991 • 2,603 citations

Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1996 • 2,543 citations

Hydrogen peroxide mediates amyloid β protein toxicity

1994 • 2,065 citations

The carboxy terminus of the .beta. amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease

1993 • 1,951 citations

Amyloid Deposits and Amyloidosis

1980 • 1,787 citations

Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ42(43)

1994 • 1,700 citations

Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein

1984 • 1,633 citations

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

1993 • 1,422 citations

Amyloid β-Protein Fibrillogenesis

1997 • 1,103 citations

Amyloid β-Protein Fibrillogenesis

1999 • 1,041 citations

Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

1999 • 917 citations

Neurotoxicity of a Fragment of the Amyloid Precursor Associated with Alzheimer's Disease

1989 • 904 citations

In vitro aging of ß-amyloid protein causes peptide aggregation and neurotoxicity

1991 • 833 citations

On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants.

1996 • 773 citations

Dynamic Light Scattering: Applications of Photon Correlation Spectroscopy

2011 • 682 citations

Water-soluble Aβ(N-40, N-42) Oligomers in Normal and Alzheimer Disease Brains

1996 • 603 citations

Evolution of amyloid: What normal protein folding may tell us about fibrillogenesis and disease

1999 • 554 citations

Morphology and Toxicity of Aβ-(1-42) Dimer Derived from Neuritic and Vascular Amyloid Deposits of Alzheimer's Disease

1996 • 482 citations

Analysis of Heterogeneous βA4 Peptides in Human Cerebrospinal Fluid and Blood by a Newly Developed Sensitive Western Blot Assay

1996 • 477 citations

Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro.

1987 • 475 citations

Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging.

1994 • 455 citations

Atomic force microscopic imaging of seeded fibril formation and fibril branching by the Alzheimer's disease amyloid-β protein

1997 • 440 citations

The toxicity in vitro of β-amyloid protein

1995 • 427 citations

Inhibition of PC12 cell redox activity is a specific,early indicator of the mechanism of beta-amyloid-mediated celldeath.

1994 • 406 citations

Aggregation of Secreted Amyloid β-Protein into Sodium Dodecyl Sulfate-stable Oligomers in Cell Culture

1995 • 365 citations

Aggregation-related toxicity of synthetic β-amyloid protein in hippocampal cultures

1991 • 280 citations

The Toxicity of the Alzheimer's β-Amyloid Peptide Correlates with a Distinct Fiber Morphology

1997 • 213 citations

Aggregation State and Neurotoxic Properties of Alzheimer Beta-Amyloid Peptide

1995 • 205 citations

Oligomerization of Endogenous and Synthetic Amyloid β-Protein at Nanomolar Levels in Cell Culture and Stabilization of Monomer by Congo Red

1998 • 184 citations

Isolation, Chemical Characterization, and Quantitation of Aβ 3-Pyroglutamyl Peptide from Neuritic Plaques and Vascular Amyloid Deposits

1997 • 174 citations

Inhibition of fibril formation in beta-amyloid peptide by a novel series of benzofurans.

1999 • 173 citations

Common structural features determine the effectiveness of carvedilol, daunomycin and rolitetracycline as inhibitors of Alzheimer beta-amyloid fibril formation.

1999 • 123 citations

Hemin and related porphyrins inhibit β‐amyloid aggregation

1997 • 98 citations

Molecular genetic approaches to Alzheimer's disease

1989 • 65 citations

Ultrastructural studies of amyloid fibrils and senile plaques in human brain

1986 • 62 citations

Computationally derived structural models of the ?-amyloid found in Alzheimer's disease plaques and the interaction with possible aggregation inhibitors

1999 • 48 citations

Heat shock partially protects rat pheochromocytoma PC12 cells from amyloid β peptide toxicity

1993 • 26 citations

Cited By (0)

Loading...