Two Distinct Compositional Classes of Vertebrate Gene-Bearing DNA Stretches, Their Structures and Possible Evolutionary Origin

Hypervariable ‘minisatellite’ regions in human DNA

1985 • 3,789 citations

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

Codon usage and tRNA content in unicellular and multicellular organisms.

1985 • 1,724 citations

Codon selection in yeast.

1982 • 1,580 citations

DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall

1985 • 1,233 citations

Molecular basis of base substitution hotspots in Escherichia coli

1978 • 1,185 citations

DNA METHYLATION AND GENE ACTIVITY

1983 • 1,115 citations

Codon catalog usage is a genome strategy modulated for gene expressivity

1981 • 951 citations

The Mosaic Genome of Warm-Blooded Vertebrates

1985 • 887 citations

Preferential codon usage in prokaryotic genes: the optimal codon-anticodon interaction energy and the selective codon usage in efficiently expressed genes

1982 • 850 citations

A fixed site of DNA replication in eucaryotic cells

1980 • 669 citations

A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA

1985 • 668 citations

Replication Timing of Genes and Middle Repetitive Sequences

1984 • 561 citations

DNA methylation: organ specific variations in the methylation pattern within and around ovalbumin and other chicken genes

1979 • 356 citations

The structure of the human zeta-globin gene and a closely linked, nearly identical pseudogene

1982 • 323 citations

Insertion of nucleotides opposite apurinic apyrimidinic sites in deoxyribonucleic acid during in vitro synthesis: uniqueness of adenine nucleotides

1983 • 320 citations

DNA methylation patterns Formation and function

1984 • 312 citations

An analysis of eukaryotic genomes by density gradient centrifugation

1976 • 242 citations

An approach to the organization of eukaryotic genomes at a macromolecular level

1976 • 215 citations

An analysis of the bovine genome by Cs2SO4—Ag+ density gradient centrifugation

1973 • 210 citations

Mid-prophase human chromosomes. The attainment of 2000 bands

1981 • 198 citations

The Major Components of the Mouse and Human Genomes

1981 • 158 citations

Altered base ratios in the DNA of an Escherichia coli mutator strain.

1967 • 153 citations

CG dinucleotide clusters in MHC genes and in 5′ demethylated genes

1984 • 146 citations

Functional Organization in the Nucleus

1982 • 145 citations

Clusters of CpG dinucleotides implicated by nuclease hypersensitivity as control elements of housekeeping genes

1985 • 145 citations

Asymmetrical distribution of CpG in an ‘average’ mammalian gene

1982 • 140 citations

Bloom's Syndrome: Evidence for an Increased Mutation Frequency in Vivo

1983 • 100 citations

Carcinogens induce targeted mutations in Escherichia coli

1982 • 93 citations

Secondary structure of MS2 phage RNA and bias in code word usage

1979 • 69 citations

ACNUC: a nucleic acid sequence data base and analysis system

1984 • 64 citations

Gene distribution and nucleotide sequence organization in the human genome

1986 • 60 citations

Supercoiled loops and the organization of replication and transcription in eukaryotes

1985 • 57 citations

Genetic changes in mammalian cells reminiscent of an SOS response

1984 • 48 citations

The DNA Components of the Chicken Genome

1979 • 48 citations

High frequency DNA rearrangements associated with mouse centromeric satellite DNA

1986 • 46 citations

Assignment of orthologous relationships among mammalian alpha-globin genes by examining flanking regions reveals a rapid rate of evolution.

1986 • 33 citations

Base composition heterogeneity of mammalian DNAs in CsCl-netropsin density gradient.

1976 • 20 citations

Deleted Work

1955 • 0 citations