Genetic changes in mammalian cells reminiscent of an SOS response

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

1983 • 1,952 citations

Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

1981 • 1,611 citations

Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli

1976 • 1,572 citations

The SOS regulatory system of Escherichia coli

1982 • 1,491 citations

Hemoglobin Synthesis in Murine Virus-Induced Leukemic Cells In Vitro: Stimulation of Erythroid Differentiation by Dimethyl Sulfoxide

1971 • 1,371 citations

The induction of gene activity in drosophila by heat shock

1979 • 1,308 citations

Cellular Oncogenes and Multistep Carcinogenesis

1983 • 1,154 citations

A regulatory upstream promoter element in the Drosophila Hsp 70 heat-shock gene

1982 • 1,038 citations

Biochemistry of Interferons and Their Actions

1982 • 868 citations

Radiosensitivity in ataxia-telangiectasia: a new explanation.

1980 • 784 citations

Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations

1983 • 719 citations

Erythroleukemic Differentiation

1978 • 694 citations

Butyric acid, a potent inducer of erythroid differentiation in cultured erythroleukemic cells

1975 • 663 citations

Persisting oncogenic herpesvirus induced by the tumour promoter TPA

1978 • 632 citations

Control of normal cell differentiation and the phenotypic reversion of malignancy in myeloid leukaemia

1978 • 593 citations

The effect of amino acid analogues and heat shock on gene expression in chicken embryo fibroblasts

1978 • 547 citations

The organization and expression of histone gene families

1981 • 501 citations

A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells

1983 • 485 citations

AppppA, heat-shock stress, and cell oxidation.

1983 • 379 citations

STRINGENT CONTROL IN E. COLI

1979 • 373 citations

DNA strand breaks and ADP-ribosyl transferase activation during cell differentiation

1982 • 351 citations

Regulation of normal differentiation in mouse and human myeloid leukemic cells by phorbol esters and the mechanism of tumor promotion

1979 • 337 citations

Antibody diversity: Somatic hypermutation of rearranged VH genes

1981 • 334 citations

Mechanism by which caffeine potentiates lethality of nitrogen mustard.

1982 • 294 citations

Ultraviolet reactivation and ultraviolet mutagenesis of λ in different genetic systems

1971 • 278 citations

Presence of diadenosine 5',5''' -P1, P4-tetraphosphate (Ap4A) in mamalian cells in levels varying widely with proliferative activity of the tissue: a possible positive "pleiotypic activator".

1976 • 269 citations

Genes, Chromosomes, and Neoplasia

1981 • 264 citations

Tumorigenesis in Mouse Skin: Inhibition by Synthetic Inhibitors of Proteases

1970 • 263 citations

Role of DNA breaks and ADP-ribosyl transferase activity in eukaryotic differentiation demonstrated in human lymphocytes

1982 • 238 citations

Clusters of point mutations are found exclusively around rearranged antibody variable genes.

1983 • 233 citations

Interferon-gamma induces enhanced expression of Ia and H-2 antigens on B lymphoid, macrophage, and myeloid cell lines.

1983 • 228 citations

Chromosome Damage and Repair

1981 • 219 citations

MUTATIONAL SPECIFICITY IN BACTERIA

1983 • 208 citations

Studies on Simian Virus 40 Excision from Cellular Chromosomes

1979 • 206 citations

Breakage of DNA and alterations in folded genomes by inducers of differentiation in Friend erythroleukemic cells.

1978 • 173 citations

Ultraviolet reactivation of herpes simplex virus is mutagenic and inducible in mammlian cells.

1978 • 164 citations

UV-induced extracellular factor from human fibroblasts communicates the UV response to nonirradiated cells

1984 • 162 citations

Differences between germ-line and rearranged immunoglobulin Vκ coding sequences suggest a localized mutation mechanism

1981 • 161 citations

Fission-spectrum neutrons at reduced dose rates enhance neoplastic transformation

1982 • 159 citations

Induction of differentiation of human myeloid leukemia cells by inhibitors of DNA synthesis.

1982 • 153 citations

Elevated spontaneous mutation rate in Bloom syndrome fibroblasts.

1981 • 150 citations

Restriction point control of cell growth by a labile protein: evidence for increased stability in transformed cells.

1982 • 150 citations

Diadenosine 5',5'''-P1,P4-tetraphosphate, a ligand of the 57-kilodalton subunit of DNA polymerase alpha.

1979 • 149 citations

Carcinogens enhance survival of UV-irradiated simian virus 40 in treated monkey kidney cells: induction of a recovery pathway?

1978 • 147 citations

Effects of altered [ADP-ribose]n metabolism on expression of fetal functions by adult hepatocytes

1982 • 144 citations

Diadenosine 5′, 5′′′-P1, P4-tetraphosphate: a pleiotropically acting alarmone?

1983 • 137 citations

Changes in DNA associated with induction of erythroid differentiation by dimethyl sulfoxide in murine erythroleukemia cells.

1978 • 132 citations

Timing of the steps in transformation of C3H 10T½ cells by X-irradiation

1984 • 128 citations

Anti‐mitogenic Function of Interferon‐Induced (2′‐5′)Oligo(adenylate) and Growth‐Related Variations in Enzymes that Synthesize and Degrade This Oligonucleotide

1981 • 122 citations

IS THERE SOS INDUCTION IN MAMMALIAN CELLS?

1980 • 121 citations

Induction of an error-prone mode of DNA repair in UV-irradiated monkey kidney cells

1980 • 120 citations

Induction of Differentiation of Human Promyelocytic Leukemia Cells (HL-60) by Nucleosides and Methotrexate

1981 • 120 citations

Clastogenic activity from Bloom syndrome fibroblast cultures.

1981 • 114 citations

Interferon enhances the expression of Fc gamma receptors.

1980 • 104 citations

Bloom's Syndrome: Evidence for an Increased Mutation Frequency in Vivo

1983 • 100 citations

Cancer genes come of age

1983 • 98 citations

Plasminogen activator: Induction of synthesis by DNA damage

1980 • 97 citations

Carcinogens induce targeted mutations in Escherichia coli

1982 • 93 citations

Characterization of the replication of Escherichia coli DNA in the absence of protein synthesis: Stable DNA replication

1975 • 91 citations

Expression of normal monocyte-macrophage differentiation antigens on HL60 promyelocytes undergoing differentiation induced by leukocyte-conditioned medium or phorbol diester

1981 • 90 citations

Enhanced survival of ultraviolet-irradiated herpes simplex virus in carcinogen-pretreated cells

1978 • 89 citations

Ultraviolet light enhanced reactivation of a mammalian virus

1970 • 86 citations

Induction of UV-resistant DNA replication in Escherichia coli: Induced stable DNA replication as an SOS function

1979 • 85 citations

Viral Probes for DNA Repair

1983 • 82 citations

Erythroid differentiation in cultured Friend leukemia cells treated with metabolic inhibitors.

1976 • 77 citations

RADIATION ENHANCED REACTIVATION OF NUCLEAR REPLICATING MAMMALIAN VIRUSES*

1977 • 74 citations

Infection of UV-irradiated xeroderma pigmentosum fibroblasts by herpes simplex virus: Study of capacity and Weigle reactivation

1976 • 74 citations

UV-REACTIVATION OF HERPES SIMPLEX VIRUS IS MUTAGENIC AND INDUCIBLE IN MAMMALIAN CELLS

1978 • 72 citations

Commitment: How do cells make the decision to differentiate?

1981 • 65 citations

Activation of an endogenous mouse type C virus by ultraviolet-irradiated herpes simplex virus types 1 and 2.

1976 • 63 citations

UV-reactivation, virus production and mutagenesis of SV40 in UV-irradiated monkey kidney cells

1980 • 62 citations

Modulation of chronic lymphocytic leukemia cells by phorbol ester: increase in Ia expression, IgM secretion and MLR stimulatory capacity.

1982 • 59 citations

"Onion skin" replication of integrated polyoma virus DNA and flanking sequences in polyoma-transformed rat cells: termination within a specific cellular DNA segment.

1983 • 53 citations

P1,P4-Di(adenosine-5')tetraphosphate inhibits phosphorylation of immunoglobulin G by Rous sarcoma virus pp60src.

1983 • 47 citations

3 Lytic Cycle of SV40 and Polyoma Virus

1980 • 46 citations

Regulation of immunoglobulin synthesis in mouse myeloma cells

1976 • 41 citations

Phorbol ester-mediated stimulation of the synthesis of mouse mammary tumour virus

1980 • 41 citations

The mechanism of untargeted mutagenesis in UV-irradiated yeast

1982 • 38 citations

Indirect induction of erythroid differentiation in mouse Friend cells: evidence for two intracellular reactions involved in the differentiation.

1983 • 38 citations

UV‐ENHANCED REACTIVATION OF MINUTE‐VIRUS‐OF‐MICE: STIMULATION OF A LATE STEP IN THE VIRAL LIFE CYCLE

1981 • 37 citations

Intervening DNA insertions and the alteration of gene expression by carcinogens.

1980 • 36 citations

Diadenosine 5', 5"'-P1,P4-tetraphosphate stimulates processing of adp-ribosylated poly(ADP-ribose) polymerase.

1983 • 36 citations

Induction of mouse mammary tumor virus RNA in mammary tumors of BALB/c mice treated with urethane, X-irradiation, and hormones

1979 • 35 citations

12-O-tetradecanoylphorbol 13-acetate-inducible proteins are synthesized at an increased rate in Bloom syndrome fibroblasts.

1982 • 34 citations

Directed mutagenesis method for analysis of mutagen specificity: application to ultraviolet-induced mutagenesis.

1983 • 33 citations

UV light-induced immunoglobulin heavy-chain class switch in a human lymphoblastoid cell line

1983 • 33 citations

A B-lymphocyte-specific high-turnover protein: Constitutive expression in resting B cells and induction of synthesis in proliferating cells

1982 • 32 citations

UV-ENHANCED VIRUS REACTIVATION IN MAMMALIAN CELLS: EFFECTS OF METABOLIC INHIBITORS*

1979 • 31 citations

W-reactivation and W-mutagenesis of gamma-irradiated phage lambda

1978 • 30 citations

Error-prone replication of ultraviolet-irradiated Simian Virus 40 in carcinogen-treated monkey kidney cells

1982 • 30 citations

γ-Ray enhanced reactivation of γ-irradiated adenovirus in human cells

1979 • 30 citations

Regulation of MHC class II invariant chain expression: induction of synthesis in human and murine plasmocytoma cells by arresting replication.

1983 • 27 citations

AMPLIFICATION OF TRANSLATIONAL CONTROL BY MEMBRANE‐MEDIATED EVENTS: A PLEIOTROPIC EFFECT ON CELLULAR AND VIRAL GENE EXPRESSION*

1980 • 27 citations

UV‐INDUCED REVERSION OF ADENOVIRUS 5ts2 INFECTING HUMAN CELLS

1981 • 27 citations

The bacterial response to DNA damage

1983 • 26 citations

Induction of mating type interconversion in a heterothallic strain of Saccharomyces cerevisiae by DNA damaging agents

1983 • 25 citations

γ-ray-enhanced reactivation of UV-irradiated adenovirus in normal human fibroblasts

1979 • 25 citations

Translocations Involving Ig-Locus-Carrying Chromosomes: A Model For Genetic Transposition in Carcinogenesis

1982 • 24 citations

Induction of Immunoglobulin Synthesis in Abelson Murine Leukemia Virus-transformed Mouse Lymphoma Cells in Culture

1977 • 24 citations

Enhanced reactivation and mutagenesis after transfection of carcinogen-treated monkey kidney cells with UV-irradiated Simian Virus 40 (SV40) DNA

1982 • 19 citations

Calcium, calmodulin and cAMP and the control of cellular proliferation

1982 • 16 citations

Mono ADP-ribosylation and poly ADP-ribosylation of proteins in normal and malignant tissues

1982 • 15 citations

Human cancer genes

1982 • 14 citations

Mammary Tumor Formation and Hormonal Control of Mouse Mammary Tumor Virus Expression

1982 • 13 citations

Mechanisms of chemical carcinogenesis

1981 • 11 citations

Simultaneous chemical induction of MTV and MLV in vitro

1977 • 7 citations

Enhanced Survival of Ultraviolet-Damaged Parvovirus LuIII and Herpes Virus in Carcinogen Pretreated Transformed Human Cells

1981 • 6 citations

Anti-glucocorticoids block the enhancement of mouse mammary tumor virus production by 12-Otetradecanoylphorbol-13-acetate

1983 • 4 citations