Gene Expression by PBMC in Primary Sclerosing Cholangitis: Evidence for Dysregulation of Immune Mediated Genes

Deregulated T Cell Activation and Autoimmunity in Mice Lacking Interleukin-2 Receptor β

1995 • 868 citations

Molecular cloning and expression of cDNAs for the human interleukin-2 receptor

1984 • 858 citations

Primary sclerosing cholangitis: a review of its clinical features, cholangiography, and hepatic histology.

1980 • 733 citations

Clinicopathologic features of the syndrome of primary sclerosing cholangitis

1980 • 555 citations

Incidence, clinical spectrum, and outcomes of primary sclerosing cholangitis in a united states community

2003 • 433 citations

TSG-6: a multifunctional protein associated with inflammation

2003 • 354 citations

A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44.

1992 • 295 citations

Association of primary sclerosing cholangitis with HLA-B8.

1983 • 270 citations

TNF/IL-1-inducible protein TSG-6 potentiates plasmin inhibition by inter-alpha-inhibitor and exerts a strong anti-inflammatory effect in vivo.

1996 • 214 citations

HLA Antigens and Immunoregulatory T Cells in Ulcerative Colitis Associated with Hepatobiliary Disease

1982 • 207 citations

TSG-6: An IL-1 /TNF-inducible protein with anti-inflammatory activity

1997 • 195 citations

Loss of transforming growth factor β signalling in the intestine contributes to tissue injury in inflammatory bowel disease

2001 • 187 citations

Increased frequency of autoimmune diseases in patients with primary sclerosing cholangitis

2000 • 184 citations

HLA class II haplotypes in primary sclerosing cholangitis patients from five European populations

1999 • 173 citations

TSG-6: a TNF-, IL-1-, and LPS-inducible secreted glycoprotein associated with arthritis.

1993 • 150 citations

Identification of novel molecules and pathogenic pathways in primary biliary cirrhosis: cDNA array analysis of intrahepatic differential gene expression

2001 • 146 citations

Increased prevalence of primary sclerosing cholangitis among first-degree relatives

2004 • 139 citations

Identification of a CD20-, FcϵRIβ-, and HTm4-Related Gene Family: Sixteen New MS4A Family Members Expressed in Human and Mouse

2001 • 131 citations

Transforming growth factor β (TGF-β) and autoimmunity

2005 • 118 citations

Expression and role of p75 interleukin 2 receptor on human monocytes.

1990 • 111 citations

TSG-6, an Arthritis-Associated Hyaluronan Binding Protein, Forms a Stable Complex with the Serum Protein Inter-.alpha.-inhibitor

1994 • 102 citations

Function associated with IL-2 receptor-beta on human neutrophils. Mechanism of activation of antifungal activity against Candida albicans by IL-2.

1993 • 97 citations

Identification of a new multigene four-transmembrane family (MS4A) related to CD20, HTm4 and β subunit of the high-affinity IgE receptor

2001 • 95 citations

Primary sclerosing cholangitis is associated to an extended B8-DR3 haplotype including particular MICA and MICB alleles

2001 • 90 citations

Cloning of a complementary DNA encoding a new mouse B lymphocyte differentiation antigen, homologous to the human B1 (CD20) antigen, and localization of the gene to chromosome 19.

1988 • 85 citations

The immunobiology of primary sclerosing cholangitis

2004 • 79 citations

Epidemiology of primary sclerosing cholangitis

2001 • 77 citations

Anti-neutrophil antibodies in primary sclerosing cholangitis

2001 • 74 citations

Lymphocyte subsets in primary sclerosing cholangitis

1987 • 64 citations

Gene mapping of the three subunits of the high affinity FcR for IgE to mouse chromosomes 1 and 19.

1989 • 63 citations

Cloning of the cDNA for a hematopoietic cell-specific protein related to CD20 and the beta subunit of the high-affinity IgE receptor: evidence for a family of proteins with four membrane-spanning regions.

1994 • 62 citations

Transcriptional regulation of TSG6, a tumor necrosis factor- and interleukin-1-inducible primary response gene coding for a secreted hyaluronan-binding protein.

1993 • 58 citations

Immunogenetics in PSC

2001 • 49 citations

Chromosome 11q13 and atopic asthma

1999 • 48 citations

In utero treatment with monoclonal antibody to IL-2 receptor β-chain completely abrogates development of Thy-1⁺ dendritic epidermal cells

1992 • 36 citations

Novel association of HLA-haplotypes with primary sclerosing cholangitis (PSC) in a southern European population

2003 • 29 citations

Expression of IL-2 receptor p55 and p75 chains by human B lymphocytes: effects of activation and differentiation.

1991 • 27 citations

Differential expression of the interleukin 2 receptor β (p75) chain on human peripheral blood natural killer subsets

1990 • 23 citations

Increased frequency of autoimmune diseases in patients with primary sclerosing cholangitis

2000 • 9 citations