Statins in Stroke Prevention and Carotid Atherosclerosis

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

1994 • 8,631 citations

The Effect of Pravastatin on Coronary Events after Myocardial Infarction in Patients with Average Cholesterol Levels

1996 • 7,450 citations

Prevention of Coronary Heart Disease with Pravastatin in Men with Hypercholesterolemia

1995 • 7,378 citations

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: a randomised placebocontrolled trial

2002 • 6,780 citations

Primary Prevention of Acute Coronary Events With Lovastatin in Men and Women With Average Cholesterol Levels

1998 • 5,293 citations

Prevention of Cardiovascular Events and Death with Pravastatin in Patients with Coronary Heart Disease and a Broad Range of Initial Cholesterol Levels

1998 • 5,229 citations

Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial—Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial

2003 • 3,816 citations

PREVENTION OF CORONARY HEART DISEASE WITH PRAVASTATIN IN MEN WITH HYPERCHOLESTEROLEMIA

1995 • 3,524 citations

Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial

2002 • 3,347 citations

MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial

2003 • 2,931 citations

Effects of Atorvastatin on Early Recurrent Ischemic Events in Acute Coronary Syndromes<SUBTITLE>The MIRACL Study: A Randomized Controlled Trial</SUBTITLE>

2001 • 2,473 citations

Simvastatin and Niacin, Antioxidant Vitamins, or the Combination for the Prevention of Coronary Disease

2001 • 1,999 citations

Antibodies to glutamic acid decarboxylase as predictors of insulin-dependent diabetes mellitus before clinical onset of disease

1994 • 1,697 citations

Measurement of C-Reactive Protein for the Targeting of Statin Therapy in the Primary Prevention of Acute Coronary Events

2001 • 1,537 citations

Inflammation, Pravastatin, and the Risk of Coronary Events After Myocardial Infarction in Patients With Average Cholesterol Levels

1998 • 1,398 citations

Major Outcomes in Moderately Hypercholesterolemic, Hypertensive Patients Randomized to Pravastatin vs Usual Care: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT)

2002 • 1,311 citations

Pleiotropic Effects of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors

2001 • 1,290 citations

Serum Cholesterol Levels and Six-Year Mortality from Stroke in 350,977 Men Screened for the Multiple Risk Factor Intervention Trial

1989 • 1,123 citations

Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20 536 people with cerebrovascular disease or other high-risk conditions

2004 • 1,050 citations

Cardiovascular Events and Their Reduction With Pravastatin in Diabetic and Glucose-Intolerant Myocardial Infarction Survivors With Average Cholesterol Levels

1998 • 1,000 citations

Pravastatin Treatment Increases Collagen Content and Decreases Lipid Content, Inflammation, Metalloproteinases, and Cell Death in Human Carotid Plaques

2001 • 995 citations

Antiatherothrombotic Properties of Statins

1998 • 972 citations

The Effect of Aggressive Lowering of Low-Density Lipoprotein Cholesterol Levels and Low-Dose Anticoagulation on Obstructive Changes in Saphenous-Vein Coronary-Artery Bypass Grafts

1997 • 954 citations

Effect of aggressive versus conventional lipid lowering on atherosclerosis progression in familial hypercholesterolemia (ASAP): a prospective, randomised, double-blind trial

2001 • 937 citations

Effect of lovastatin on early carotid atherosclerosis and cardiovascular events. Asymptomatic Carotid Artery Progression Study (ACAPS) Research Group.

1994 • 887 citations

Cholesterol, diastolic blood pressure, and stroke: 13 000 strokes in 450 000 people in 45 prospective cohorts

1995 • 852 citations

Effects of Lipid Lowering by Pravastatin on Progression and Regression of Coronary Artery Disease in Symptomatic Men With Normal to Moderately Elevated Serum Cholesterol Levels

1995 • 846 citations

Stroke: Pathophysiology, Diagnosis, and Management.

1988 • 763 citations

Cholesterol Lowering With Statin Drugs, Risk of Stroke, and Total Mortality

1997 • 737 citations

Implications of Small Reductions in Diastolic Blood Pressure for Primary Prevention

1995 • 736 citations

Cholesterol Reduction in Cardiovascular Disease — Clinical Benefits and Possible Mechanisms

1995 • 676 citations

Effect of simvastatin on coronary atheroma: the Multicentre Anti-Atheroma Study (MAAS)

1994 • 648 citations

Coronary Angiographic Changes with Lovastatin Therapy: The Monitored Atherosclerosis Regression Study (MARS)

1993 • 637 citations

Pravastatin, lipids, and atherosclerosis in the carotid arteries (PLAC-II)

1995 • 612 citations

ARBITER: Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol

2002 • 557 citations

Kuopio Atherosclerosis Prevention Study (KAPS)

1995 • 557 citations

Treatment with Atorvastatin to the National Cholesterol Educational Program Goal Versus 'Usual' Care in Secondary Coronary Heart Disease Prevention

2002 • 537 citations

Cholesterol Lowering With Statin Drugs, Risk of Stroke, and Total Mortality

1998 • 509 citations

The design of a prospective study of pravastatin in the elderly at risk (PROSPER)

1999 • 451 citations

Pravastatin limitation of atherosclerosis in the coronary arteries (PLAC I): Reduction in atherosclerosis progression and clinical events

1995 • 431 citations

Cholesterol and all-cause mortality in elderly people from the Honolulu Heart Program: a cohort study

2001 • 423 citations

Influence of total cholesterol, high density lipoprotein cholesterol, and triglycerides on risk of cerebrovascular disease: the Copenhagen city heart study

1994 • 369 citations

Pravastatin Therapy and the Risk of Stroke

2000 • 339 citations

Cumulative Effects of High Cholesterol Levels, High Blood Pressure, and Cigarette Smoking on Carotid Stenosis

1997 • 329 citations

Stroke, Statins, and Cholesterol

1997 • 316 citations

Serum cholesterol and hemorrhagic stroke in the Honolulu Heart Program.

1989 • 308 citations

Lack of Effect of Lovastatin on Restenosis after Coronary Angioplasty

1994 • 291 citations

Reduction of Stroke Events With Pravastatin

2001 • 284 citations

Effect of the HMG-CoA Reductase Inhibitors on Blood Pressure in Patients With Essential Hypertension and Primary Hypercholesterolemia

1999 • 281 citations

Long-Term Effects of Cholesterol Lowering and Angiotensin-Converting Enzyme Inhibition on Coronary Atherosclerosis

2000 • 268 citations

Pravastatin reduces carotid intima-media thickness progression in an asymptomatic hypercholesterolemic Mediterranean population: The Carotid Atherosclerosis Italian Ultrasound Study

1996 • 265 citations

B-Mode Ultrasound Assessment of Pravastatin Treatment Effect on Carotid and Femoral Artery Walls and Its Correlations With Coronary Arteriographic Findings: A Report of the Regression Growth Evaluation Statin Study (REGRESS)

1998 • 264 citations

Effects of Lowering Average or Below-Average Cholesterol Levels on the Progression of Carotid Atherosclerosis

1998 • 258 citations

Epidemiology of Stroke

2004 • 241 citations

Reductase Inhibitor Monotherapy and Stroke Prevention

1997 • 213 citations

Effects of Atorvastatin on Stroke in Patients With Unstable Angina or Non-Q-Wave Myocardial Infarction

2002 • 194 citations

Design and Baseline Characteristics of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Study

2003 • 187 citations

Effects of pravastatin in patients with serum total cholesterol levels from 5.2 to 7.8 mmol/liter (200 to 300 mg/dl) plus two additional atherosclerotic risk factors

1993 • 176 citations

Low Concentration of Serum Total Cholesterol Is Associated With Multifocal Signal Loss Lesions on Gradient-Echo Magnetic Resonance Imaging

2002 • 172 citations

Cross-Sectional and 4-Year Longitudinal Associations Between Brachial Pulse Pressure and Common Carotid Intima-Media Thickness in a General Population

1999 • 144 citations

Hypercholesterolemia, lipid-lowering agents, and the risk for brain infarction

2001 • 83 citations

Pravastatin, lipids, and atherosclerosis in the carotid arteries: Design features of a clinical trial with carotid atherosclerosis outcome

1992 • 68 citations

Effects of Cholesterol Lowering on the Progression of Coronary Atherosclerosis in Women

1995 • 66 citations

Pravastatin Use and Risk of Coronary Events and Cerebral Infarction in Japanese Men with Moderate Hypercholesterolemia : The Kyushu Lipid Intervention Study

2000 • 66 citations

Effect of simvastatin on coronary atheroma

1994 • 51 citations

Effect of Cholesterol-Lowering Medications on Progression of Mild Atherosclerotic Lesions of the Carotid Arteries and on the Risk of Stroke

1995 • 26 citations

Baseline characteristics of subjects in the lipoprotein and coronary atherosclerosis study (LCAS) with fluvastatin

1994 • 18 citations

Deleted Work

1955 • 0 citations