Cholesterol Lowering With Statin Drugs, Risk of Stroke, and Total Mortality

Statistical Aspects of the Analysis of Data From Retrospective Studies of Disease

1959 • 14,850 citations

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

1994 • 8,631 citations

The Effect of Pravastatin on Coronary Events after Myocardial Infarction in Patients with Average Cholesterol Levels

1996 • 7,450 citations

Prevention of Coronary Heart Disease with Pravastatin in Men with Hypercholesterolemia

1995 • 7,378 citations

PREVENTION OF CORONARY HEART DISEASE WITH PRAVASTATIN IN MEN WITH HYPERCHOLESTEROLEMIA

1995 • 3,524 citations

Beta blockade during and after myocardial infarction: An overview of the randomized trials

1985 • 3,248 citations

Regression of Coronary Artery Disease as a Result of Intensive Lipid-Lowering Therapy in Men with High Levels of Apolipoprotein B

1990 • 2,192 citations

By how much and how quickly does reduction in serum cholesterol concentration lower risk of ischaemic heart disease?

1994 • 1,235 citations

Serum Cholesterol Levels and Six-Year Mortality from Stroke in 350,977 Men Screened for the Multiple Risk Factor Intervention Trial

1989 • 1,123 citations

The Effect of Cholesterol-Lowering and Antioxidant Therapy on Endothelium-Dependent Coronary Vasomotion

1995 • 1,123 citations

Lowering cholesterol concentrations and mortality: a quantitative review of primary prevention trials.

1990 • 971 citations

Effect of lovastatin on early carotid atherosclerosis and cardiovascular events. Asymptomatic Carotid Artery Progression Study (ACAPS) Research Group.

1994 • 887 citations

Cholesterol, diastolic blood pressure, and stroke: 13 000 strokes in 450 000 people in 45 prospective cohorts

1995 • 852 citations

Effects of Lipid Lowering by Pravastatin on Progression and Regression of Coronary Artery Disease in Symptomatic Men With Normal to Moderately Elevated Serum Cholesterol Levels

1995 • 846 citations

HMG-CoA Reductase Inhibitors for Treatment of Hypercholesterolemia

1988 • 760 citations

Effect of simvastatin on coronary atheroma: the Multicentre Anti-Atheroma Study (MAAS)

1994 • 648 citations

Coronary Angiographic Changes with Lovastatin Therapy: The Monitored Atherosclerosis Regression Study (MARS)

1993 • 637 citations

Pravastatin, lipids, and atherosclerosis in the carotid arteries (PLAC-II)

1995 • 612 citations

Kuopio Atherosclerosis Prevention Study (KAPS)

1995 • 557 citations

Effects of monotherapy with an HMG-CoA reductase inhibitor on the progression of coronary atherosclerosis as assessed by serial quantitative arteriography. The Canadian Coronary Atherosclerosis Intervention Trial.

1994 • 504 citations

Expanded Clinical Evaluation of Lovastatin (EXCEL) study results. I. Efficacy in modifying plasma lipoproteins and adverse event profile in 8245 patients with moderate hypercholesterolemia

1991 • 489 citations

Pravastatin limitation of atherosclerosis in the coronary arteries (PLAC I): Reduction in atherosclerosis progression and clinical events

1995 • 431 citations

The Value of Lowering Cholesterol after Myocardial Infarction

1990 • 427 citations

Should there be a moratorium on the use of cholesterol lowering drugs?

1992 • 345 citations

Serum cholesterol and hemorrhagic stroke in the Honolulu Heart Program.

1989 • 308 citations

Lack of Effect of Lovastatin on Restenosis after Coronary Angioplasty

1994 • 291 citations

Cholesterol Reduction Yields Clinical Benefit

1995 • 283 citations

Reduction in Cardiovascular Events During Pravastatin Therapy

1995 • 283 citations

An analysis of randomized trials evaluating the effect of cholesterol reduction on total mortality and coronary heart disease incidence.

1990 • 247 citations

Cholesterol Reduction and the Risk for Stroke in Men

1993 • 216 citations

Current Status of Risk Factors for Stroke

1983 • 193 citations

Effect on coronary atherosclerosis of decrease in plasma cholesterol concentrations in normocholesterolaemic patients

1994 • 187 citations

Prevention of restenosis by lovastatin after successful coronary angioplasty

1991 • 165 citations

Might treatment of hypercholesterolaemia increase non-cardiac mortality?

1991 • 161 citations

Lipid-lowering interventions in angiographic trials

1995 • 115 citations

Treatment of osteoporosis with human parathyroid peptide and observations on effect of sodium fluoride.

1990 • 114 citations

An Overview of Trials of Cholesterol Lowering and Risk of Stroke

1995 • 109 citations

Expanded Clinical Evaluation of Lovastatin (EXCEL) study results. Effect of patient characteristics on lovastatin-induced changes in plasma concentrations of lipids and lipoproteins.

1992 • 82 citations

Pravastatin, lipids, and major coronary events

1994 • 81 citations

Prescribed Use of Cholesterol-Lowering Drugs in the United States, 1978 Through 1988

1990 • 71 citations

Pravastatin, lipids, and atherosclerosis in the carotid arteries: Design features of a clinical trial with carotid atherosclerosis outcome

1992 • 68 citations

Once‐daily pravastatin in patients with primary hypercholesterolemia: A dose‐response study

1991 • 66 citations

Cholesterol reduction and its impact on coronary artery disease and total mortality

1995 • 61 citations

Does Lowering Cholesterol Cause Cancer?

1996 • 43 citations

Expanded clinical evaluation of lovastatin (EXCEL) study: Design and patient characteristics of a double-blind, placebo-controlled study in patients with moderate hypercholesterolemia

1990 • 39 citations

Effect of cholesterol reduction by simvastatin on progression of coronary atherosclerosis: Design, baseline characteristics, and progress of the Multicenter Anti-Atheroma Study (MAAS)

1993 • 25 citations

Cholesterol Reduction: Weighing the Benefits and Risks

1996 • 24 citations

Design features of a controlled clinical trial to assess the effect of an HMG CoA reductase inhibitor on the progression of coronary artery disease

1993 • 18 citations