Increased serum transforming growth factor-β1 in human colorectal cancer correlates with reduced circulating dendritic cells and increased colonic Langerhans cell infiltration

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Immunobiology of Dendritic Cells

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Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells

1996 • 1,908 citations

Dendritic Cells Induce Peripheral T Cell Unresponsiveness under Steady State Conditions in Vivo

2001 • 1,845 citations

Natural adjuvants: Endogenous activators of dendritic cells

1999 • 1,611 citations

Langerin, a Novel C-Type Lectin Specific to Langerhans Cells, Is an Endocytic Receptor that Induces the Formation of Birbeck Granules

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Clinical significance of defective dendritic cell differentiation in cancer.

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Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells

1993 • 595 citations

In Breast Carcinoma Tissue, Immature Dendritic Cells Reside within the Tumor, Whereas Mature Dendritic Cells Are Located in Peritumoral Areas

1999 • 540 citations

A Novel Lysosome-Associated Membrane Glycoprotein, DC-LAMP, Induced upon DC Maturation, Is Transiently Expressed in MHC Class II Compartment

1998 • 402 citations

TGF-beta 1 prevents the noncognate maturation of human dendritic Langerhans cells.

1999 • 379 citations

Volume determinations using computed tomography

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Pitfalls in the Measurement of Circulating Vascular Endothelial Growth Factor

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TGF-beta 1 promotes in vitro development of dendritic cells from CD34+ hemopoietic progenitors.

1996 • 312 citations

TGF-β1 Prevents the Noncognate Maturation of Human Dendritic Langerhans Cells

1999 • 303 citations

Is cancer dangerous to the immune system?

1996 • 296 citations

High levels of transforming growth factor beta 1 in patients with colorectal cancer: Association with disease progression

1996 • 285 citations

The monoclonal antibody DCGM4 recognizes Langerin, a protein specific of Langerhans cells, and is rapidly internalized from the cell surface

1999 • 282 citations

Antigen decoding by T lymphocytes: from synapses to fate determination

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Dendritic cells: a link between innate and adaptive immunity.

1999 • 228 citations

Contrasting Effects of TGF‐β1 and TNF‐α on the Development of Dendritic Cells from Progenitors in Mouse Bone Marrow

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TGF-β1 regulation of dendritic cells

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S-100 protein-positive dendritic cells in colorectal adenocarcinomas. Distribution and relation to the clinical prognosis

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Inflammatory cells infiltrating human colorectal carcinomas express HLA class II but not B7-1 and B7-2 costimulatory molecules of the T-cell activation.

1996 • 160 citations

Defective Function of Langerhans Cells in Tumor-Bearing Animals Is the Result of Defective Maturation from Hemopoietic Progenitors

1998 • 154 citations

Dendritic cells: Immunological sentinels with a central role in health and disease

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Determination of vascular endothelial growth factor (VEGF) in circulating blood: significance of VEGF in various leucocytes and platelets

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Elevated serum levels of transforming growth factor-?1 in patients with colorectal carcinoma

1999 • 140 citations

Respective involvement of TGF-β and IL-4 in the development of Langerhans cells and non-Langerhans dendritic cells from CD34+ progenitors

1999 • 136 citations

The Host-Pathogen Interaction

2001 • 132 citations

CD34+ cell-derived CD14+ precursor cells develop into Langerhans cells in a TGF-beta 1-dependent manner.

1999 • 126 citations

TGF-beta 1 promotes in vitro generation of dendritic cells by protecting progenitor cells from apoptosis.

1997 • 115 citations

Prognostic impact of matched preoperative plasma and serum VEGF in patients with primary colorectal carcinoma

2002 • 109 citations

Effect of Vascular Endothelial Growth Factor and FLT3 Ligand on Dendritic Cell Generation In Vivo

1999 • 107 citations

Abnormally enhanced blood concentrations of vascular endothelial growth factor (VEGF) in metastatic cancer patients and their relation to circulating dendritic cells, IL-12 and endothelin-1.

2001 • 101 citations

CD34+ Cell-Derived CD14+ Precursor Cells Develop into Langerhans Cells in a TGF-β1-Dependent Manner

1999 • 100 citations

Dendritic Cell Infiltration in Colon Cancer

2001 • 94 citations

Transforming Growth Factor-β1 Polarizes Murine Hematopoietic Progenitor Cells to Generate Langerhans Cell-Like Dendritic Cells Through a Monocyte/Macrophage Differentiation Pathway

1999 • 89 citations

Soluble vascular endothelial growth factor levels in patients with primary colorectal carcinoma

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Statistics Notes: Comparing several groups using analysis of variance

1996 • 86 citations

Plasma vascular endothelial but not fibroblast growth factor levels correlate with colorectal liver metastasis vascularity and volume

2000 • 61 citations

Multidimensional flow-cytometric analysis of dendritic cells in peripheral blood of normal donors and cancer patients

1998 • 60 citations

Lineage-negative human leukocyte antigen-DR+ cells with the phenotype of undifferentiated dendritic cells in patients with carcinoma of the abdomen and pelvis.

1998 • 57 citations

Prognostic value of plasma vascular endothelial growth factor in patients with colorectal cancer.

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Role of Tumor Cell Apoptosis in Tumor Antigen Migration to the Draining Lymph Nodes

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Comparative loss and maturation of peripheral blood dendritic cell subpopulations in African and non-African HIV-1-infected patients

2001 • 42 citations

Circulating dendritic cells in early and advanced cancer patients: diminished percent in the metastatic disease.

2000 • 40 citations

Tumor Immunology

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Measurement of response to treatment in colorectal liver metastases

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Circulating Immature and Mature Dendritic Cells in Relation to Lymphocyte Subsets in Patients with Gastrointestinal Tract Cancer

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Immunohistochemical evidence of immune responses to tumor-associated antigens in lymph nodes of colon carcinoma patients

1991 • 14 citations

Association between extent of colonic mucosal sialomucin change and subsequent local recurrence after curative excision of primary colorectal cancer

1990 • 8 citations