CD34+ Cell-Derived CD14+ Precursor Cells Develop into Langerhans Cells in a TGF-β1-Dependent Manner

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

1994 • 5,204 citations

Proliferating dendritic cell progenitors in human blood.

1994 • 1,922 citations

Determination of lymphocyte division by flow cytometry

1994 • 1,712 citations

GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells

1992 • 1,608 citations

CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alpha.

1996 • 962 citations

The Transforming Growth Factor-βs

1990 • 741 citations

The cell biology of transforming growth factor β

1990 • 537 citations

Transforming Growth Factor β1, in the Presence of Granulocyte/Macrophage Colony-stimulating Factor and Interleukin 4, Induces Differentiation of Human Peripheral Blood Monocytes into Dendritic Langerhans Cells

1998 • 507 citations

Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response.

1997 • 489 citations

A Role for Endogenous Transforming Growth Factor β1 in Langerhans Cell Biology: The Skin of Transforming Growth Factor β1 Null Mice Is Devoid of Epidermal Langerhans Cells

1996 • 479 citations

CD34+ Hematopoietic Progenitors From Human Cord Blood Differentiate Along Two Independent Dendritic Cell Pathways in Response to Granulocyte-Macrophage Colony-Stimulating Factor Plus Tumor Necrosis Factor α: II. Functional Analysis

1997 • 442 citations

The Cytokine Profile Expressed by Human Dendritic Cells Is Dependent on Cell Subtype and Mode of Activation

1998 • 436 citations

B cell differentiation and isotype switching is related to division cycle number.

1996 • 393 citations

Expression of functional high affinity immunoglobulin E receptors (Fc epsilon RI) on monocytes of atopic individuals.

1994 • 378 citations

Expansion of immunostimulatory dendritic cells among the myeloid progeny of human CD34+ bone marrow precursors cultured with c-kit ligand, granulocyte-macrophage colony-stimulating factor, and TNF-alpha.

1995 • 350 citations

Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets.

1993 • 347 citations

Peripheral blood dendritic cells express Fc epsilon RI as a complex composed of Fc epsilon RI alpha- and Fc epsilon RI gamma-chains and can use this receptor for IgE-mediated allergen presentation.

1996 • 332 citations

TGF-beta 1 promotes in vitro development of dendritic cells from CD34+ hemopoietic progenitors.

1996 • 312 citations

TGF-β1 Prevents the Noncognate Maturation of Human Dendritic Langerhans Cells

1999 • 303 citations

Generation of human dendritic cells/Langerhans cells from circulating CD34+ hematopoietic progenitor cells

1996 • 259 citations

Dynamics and Requirements of T Cell Clonal Expansion In Vivo at the Single-Cell Level: Effector Function Is Linked to Proliferative Capacity

1999 • 253 citations

A Skin Homing Molecule Defines the Langerhans Cell Progenitor in Human Peripheral Blood

1997 • 173 citations

A role for TGFbeta1 in langerhans cell biology. Further characterization of the epidermal Langerhans cell defect in TGFbeta1 null mice.

1997 • 125 citations

TGF-beta 1 promotes in vitro generation of dendritic cells by protecting progenitor cells from apoptosis.

1997 • 115 citations