Carrier mediated delivery of NGF: alterations in basal forebrain neurons in aged rats revealed using antibodies against low and high affinity NGF receptors.

Central cholinergic pathways in the rat: An overview based on an alternative nomenclature (Ch1–Ch6)

1983 • 2,305 citations

The trk proto-oncogene encodes a receptor for nerve growth factor

1991 • 1,396 citations

Nerve Growth Factor Treatment After Brain Injury Prevents Neuronal Death

1987 • 942 citations

Functional Interactions of Neurotrophins and Neurotrophin Receptors

1995 • 825 citations

NGF-Mediated increase of choline acetyltransferase (ChAT) in the neonatal rat forebrain: Evidence for a physiological role of NGF in the brain?

1983 • 725 citations

Neurotrophin receptors: A window into neuronal differentiation

1992 • 704 citations

Specific retrograde transport of nerve growth factor (NGF) from neocortex to nucleus basalis in the rat

1984 • 598 citations

Neurotrophin signal transduction by the Trk receptor

1994 • 511 citations

Choline Acetyltransferase Activity in Striatum of Neonatal Rats Increased by Nerve Growth Factor

1985 • 483 citations

Nerve growth factor (NGF) in the rat CNS: Absence of specific retrograde axonal transport and tyrosine hydroxylase induction in locus coeruleus and substantia nigra

1979 • 422 citations

p140trk mRNA marks NGF-responsive forebrain neurons: Evidence that trk gene expression is induced by NGF

1992 • 371 citations

p75LNGFR regulates Trk signal transduction and NGF-induced neuronal differentiation in MAH cells

1994 • 353 citations

Function and evolution in the NGF family and its receptors

1992 • 338 citations

Degenerative Changes in Forebrain Cholinergic Nuclei Correlate with Cognitive Impairments in Aged Rats

1989 • 335 citations

TrkA‐immunoreactive profiles in the central nervous system: Colocalization with neurons containing p75 nerve growth factor receptor, choline acetyltransferase, and serotonin

1994 • 330 citations

Blood-Brain Barrier Penetration and in Vivo Activity of an NGF Conjugate

1993 • 316 citations

Keeping track of neurotrophin receptors

1991 • 297 citations

Progressive decline in spatial learning and integrity of forebrain cholinergic neurons in rats during aging

1992 • 294 citations

Developmental Neurobiology and the Natural History of Nerve Growth Factor

1982 • 289 citations

Memory impairments following basal forebrain lesions

1985 • 264 citations

NGF improves spatial memory in aged rodents as a function of age

1991 • 263 citations

Nerve growth factor receptor and choline acetyltransferase colocalization in neurons within the rat forebrain: Response to fimbria‐fornix transection

1989 • 255 citations

Brain-derived neurotrophic factor (BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection

1993 • 254 citations

NGF-stimulated retrograde transport of trkA in the mammalian nervous system.

1995 • 239 citations

Expression of Functional Nerve Growth Factor Receptors After Gene Transfer

1989 • 235 citations

Detection of NGF-like activity in human brain tissue: increased levels in Alzheimer's disease

1993 • 234 citations

Nerve growth factor in Alzheimerʼs disease: defective retrograde transport to nucleus basalis

1995 • 226 citations

Regulation of TrkA and ChAT expression in developing rat basal forebrain: evidence that both exogenous and endogenous NGF regulate differentiation of cholinergic neurons

1995 • 224 citations

TrkA cross-linking mimics neuronal responses to nerve growth factor.

1994 • 222 citations

Differential Actions of Neurotrophins in the Locus Coeruleus and Basal Forebrain

1993 • 212 citations

Characteristics of memory impairment following lesioning of the basal forebrain and medial septal nucleus in rats

1987 • 194 citations

Human nerve growth factor improves spatial memory in aged but not in young rats

1994 • 193 citations

Reversal of spatial memory impairments in aged rats by nerve growth factor and neurotrophins 3 and 4/5 but not by brain-derived neurotrophic factor.

1994 • 172 citations

Localization of nerve growth factor receptors in the normal human brain and in Alzheimer's disease

1989 • 168 citations

Somatic gene transfer of NGF to the aged brain: behavioral and morphological amelioration

1995 • 161 citations

High-affinity nerve growth factor receptor (Trk) immunoreactivity is localized in cholinergic neurons of the basal forebrain and striatum in the adult rat brain

1993 • 148 citations

Systemic Administration of a Nerve Growth Factor Conjugate Reverses Age-Related Cognitive Dysfunction and Prevents Cholinergic Neuron Atrophy

1996 • 142 citations

Age-related loss of nerve growth factor sensitivity in rat basal forebrain neurons

1988 • 128 citations

HSV-1 vector-mediated gene transfer of the human nerve growth factor receptor p75hNGFR defines high-affinity NGF binding

1993 • 127 citations

Intravenous administration of a transferrin receptor antibody-nerve growth factor conjugate prevents the degeneration of cholinergic striatal neurons in a model of Huntington disease.

1994 • 123 citations

Reduced transport of [125I]nerve growth factor by cholinergic neurons and down-regulated trka expression in the medial septum of aged rats

1994 • 121 citations

Loss of NGF receptor immunoreactivity in basal forebrain neurons of aged rats: correlation with spatial memory impairment

1989 • 119 citations

Aging is associated with a diffuse impairment of forebrain cholinergic neurons

1990 • 114 citations

NGF and anti-transferrin receptor antibody conjugate: short and long-term effects on survival of cholinergic neurons in intraocular septal transplants.

1994 • 108 citations

Axonal atrophy in aging is associated with a decline in neurofilament gene expression

1995 • 98 citations

Concentration-dependent regulation of neuronal gene expression by nerve growth factor

1992 • 94 citations

Age-dependent loss and compensatory changes of septohippocampal cholinergic neurons in two rat strains differing in longevity and response to stress

1987 • 88 citations

Delivery of Trophic Factors to the Primate Brain

1993 • 85 citations

Nerve growth factor increases extracellular acetylcholine levels in the parietal cortex and hippocampus of aged rats and restores object recognition

1994 • 80 citations

Morphologic alterations of choline acetyltransferase-positive neurons in the basal forebrain of aged behaviorally characterized fisher 344 rats

1993 • 73 citations

Distribution of [125I]nerve growth factor in the rat brain following a single intraventricular injection: Correlation with the topographical distribution of trk a messenger RNA-expressing cells

1993 • 63 citations

Involvement of Nerve Growth Factor and Its Receptor in the Regulation of the Cholinergic Function in Aged Rats

1991 • 60 citations

Nerve growth factor‐like immunoreactive profiles in the primate basal forebrain and hippocampal formation

1994 • 58 citations

Age-dependent loss of cholinergic neurones in basal ganglia of rats

1988 • 46 citations

Regional changes in ngf receptor immunohistochemical labeling in the septum of the aged rat

1990 • 40 citations

Anti-NGF treatment blocks the upregulation of NGF receptor mRNA expression associated with collateral sprouting of rat dorsal root ganglion neurons

1995 • 38 citations

Placental Alkaline Phosphatase Types and Transplacental IgG Transport

1995 • 32 citations

Chapter 2 Axonal transport of the trkA high-affinity NGF receptor

1994 • 12 citations