Transcriptional control of herpesvirus gene expression: gene functions required for positive and negative regulation.

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Regulation of Herpesvirus Macromolecular Synthesis I. Cascade Regulation of the Synthesis of Three Groups of Viral Proteins

1974 • 1,479 citations

Transcriptional regulation of the ovalbumin and conalbumin genes by steroid hormones in chick oviduct.

1979 • 975 citations

Transcriptional regulation of hemoglobin switching in chicken embryos.

1981 • 800 citations

Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptides.

1975 • 616 citations

Identification of herpes simplex virus DNA sequences which encode a trans-acting polypeptide responsible for stimulation of immediate early transcription

1984 • 567 citations

Control of herpes simplex virus type 1 mRNA synthesis in cells infected with wild-type virus or the temperature-sensitive mutant tsK

1979 • 496 citations

Regulation of α genes of herpes simplex virus: Expression of chimeric genes produced by fusion of thymidine kinase with α gene promoters

1981 • 449 citations

Fine-structure mapping and functional analysis of temperature-sensitive mutants in the gene encoding the herpes simplex virus type 1 immediate early protein VP175

1980 • 436 citations

A herpes simplex virus type 1 function continuously required for early and late virus RNA synthesis

1980 • 429 citations

Characterization of the herpes simplex virion-associated factor responsible for the induction of alpha genes

1983 • 423 citations

Trans activation of transcription by herpes virus products: requirement for two HSV-1 immediate-early polypeptides for maximum activity.

1984 • 396 citations

Evidence for a direct role for both the 175,000- and 110,000-molecular-weight immediate-early proteins of herpes simplex virus in the transactivation of delayed-early promoters

1985 • 345 citations

Structural features of the herpes simplex virus alpha gene 4, 0, and 27 promoter-regulatory sequences which confer alpha regulation on chimeric thymidine kinase genes

1982 • 315 citations

Herpes simplex virus mutants defective in the virion-associated shutoff of host polypeptide synthesis and exhibiting abnormal synthesis of alpha (immediate early) viral polypeptides

1983 • 293 citations

Temporal regulation of herpes simplex virus type 1 transcription: location of transcripts on the viral genome

1977 • 274 citations

Transcriptional Regulation of Hemoglobin Switching in Chicken Embryos

1981 • 265 citations

Molecular genetics of herpes simplex virus. VII. Characterization of a temperature-sensitive mutant produced by in vitro mutagenesis and defective in DNA synthesis and accumulation of gamma polypeptides

1981 • 264 citations

Stimulation of expression of a herpes simplex virus DNA-binding protein by two viral functions.

1985 • 242 citations

Detailed analysis of the portion of the herpes simplex virus type 1 genome encoding glycoprotein C

1983 • 230 citations

Regulation of herpesvirus macromolecular synthesis. VIII. The transcription program consists of three phases during which both extent of transcription and accumulation of RNA in the cytoplasm are regulated

1979 • 169 citations

Stimulation of Expression of a Herpes Simplex Virus DNA-Binding Protein by Two Viral Functions

1985 • 165 citations

Transcriptional and genetic analyses of the herpes simplex virus type 1 genome: coordinates 0.29 to 0.45

1984 • 160 citations

Viral DNA synthesis is required for the efficient expression of specific herpes simplex virus type 1 mRNA species

1980 • 152 citations

Mode of inhibition of Herpes simplex virus DNA polymerase by phosphonoacetate

1975 • 138 citations

Definition of a series of stages in the association of two herpesviral proteins with the cell nucleus

1982 • 129 citations

Temperature-sensitive mutants in herpes simplex virus type 1 ICP4 permissive for early gene expression

1984 • 122 citations

Molecular genetics of herpes simplex virus: Demonstration of regions of obligatory and nonobligatory identity within diploid regions of the genome by sequence replacement and insertion

1978 • 115 citations

RNA synthesis in cells infected with herpes simplex virus. X. Properties of viral symmetric transcripts and of double-stranded RNA prepared from them

1975 • 111 citations

Temperature-sensitive mutants of herpes simplex virus type 1 defective in lysis but not in transformation

1975 • 100 citations

Functional analysis of a herpes simplex virus type 1 promoter: identification of far-upstream regulatory sequences

1983 • 98 citations

Regulation of Herpesvirus Macromolecular Synthesis: Nuclear Retention of Nontranslated Viral RNA Sequences

1974 • 86 citations

gamma 2-Thymidine kinase chimeras are identically transcribed but regulated a gamma 2 genes in herpes simplex virus genomes and as beta genes in cell genomes.

1985 • 85 citations

DNA-Binding Proteins of Cells Infected by Herpes Simplex Virus Type 1 and Type 2

1976 • 77 citations

Mutations in the major DNA-binding protein gene of herpes simplex virus type 1 result in increased levels of viral gene expression

1983 • 75 citations

Identification of a herpes simplex virus function that represses late gene expression from parental viral genomes

1985 • 63 citations

An immunoassay for the study of DNA-binding activities of herpes simplex virus protein ICP8

1985 • 62 citations

Characterization of the major mRNAs transcribed from the genes for glycoprotein B and DNA-binding protein ICP8 of herpes simplex virus type 1

1984 • 62 citations

Characterization of two conformational forms of the major DNA-binding protein encoded by herpes simplex virus 1

1982 • 58 citations

Characterization of a major late herpes simplex virus type 1 mRNA

1981 • 53 citations

γ₂-Thymidine Kinase Chimeras Are Identically Transcribed but Regulated a γ₂ Genes in Herpes Simplex Virus Genomes and as β Genes in Cell Genomes

1985 • 53 citations

Isolation and localization of herpes simplex virus type 1 mRNA abundant before viral DNA synthesis

1979 • 46 citations

A genetic enrichment for mutations constructed by oligodeoxynucleotide-directed mutagenesis

1985 • 45 citations