Mutations in the major DNA-binding protein gene of herpes simplex virus type 1 result in increased levels of viral gene expression

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

A membrane-filter technique for the detection of complementary DNA

1966 • 3,996 citations

Analysis of restriction fragments of T7 DNA and determination of molecular weights by electrophoresis in neutral and alkaline gels

1977 • 1,607 citations

Regulation of Herpesvirus Macromolecular Synthesis I. Cascade Regulation of the Synthesis of Three Groups of Viral Proteins

1974 • 1,479 citations

Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs

1979 • 756 citations

Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptides.

1975 • 616 citations

The binding site on SV40 DNA for a T antigen-related protein

1978 • 542 citations

Fine-structure mapping and functional analysis of temperature-sensitive mutants in the gene encoding the herpes simplex virus type 1 immediate early protein VP175

1980 • 436 citations

A herpes simplex virus type 1 function continuously required for early and late virus RNA synthesis

1980 • 429 citations

Effect of Growth Conditions on the Formation of the Relaxation Complex of Supercoiled ColE1 Deoxyribonucleic Acid and Protein in Escherichia coli

1972 • 351 citations

Molecular genetics of herpes simplex virus. VII. Characterization of a temperature-sensitive mutant produced by in vitro mutagenesis and defective in DNA synthesis and accumulation of gamma polypeptides

1981 • 264 citations

T antigen repression of SV40 early transcription from two promoters

1981 • 247 citations

THE ISOLATION AND PROPERTIES OF A VARIANT OF HERPES SIMPLEX PRODUCING MULTINUCLEATED GIANT CELLS IN MONOLAYER CULTURES IN THE PRESENCE OF ANTIBODY1

1959 • 232 citations

Relationship Between the Envelope and the Infectivity of Herpes Simplex Virus.

1964 • 220 citations

Cloning of herpes simplex virus type 1 sequences representing the whole genome

1981 • 202 citations

Temperature-sensitive mutants of herpes simplex virus type 1: Isolation, complementation and partial characterization

1973 • 200 citations

BamI, KpnI, and SalI restriction enzyme maps of the DNAs of herpes simplex virus strains Justin and F: occurrence of heterogeneities in defined regions of the viral DNA

1979 • 189 citations

Genetic analysis of temperature-sensitive mutants which define the gene for the major herpes simplex virus type 1 DNA-binding protein

1983 • 179 citations

Mutations that allow human Ad2 and Ad5 to express late genes in monkey cells map in the viral gene encoding the 72K DNA binding protein

1979 • 170 citations

Separation and characterization of herpes simplex virus type 1 immediate-early mRNA's

1979 • 155 citations

An adenovirus type 5 gene function required for initiation of viral DNA replication

1975 • 147 citations

Regulation of early adenovirus transcription: A protein product of early region 2 specifically represses region 4 transcription

1980 • 141 citations

The stability of early adenovirus mRNA is controlled by the viral 72 kd DNA-binding protein

1981 • 134 citations

Definition of a series of stages in the association of two herpesviral proteins with the cell nucleus

1982 • 129 citations

DNA synthesis and DNA polymerase activity of herpes simplex virus type 1 temperature-sensitive mutants

1975 • 120 citations

Regulation of herpesvirus macromolecular synthesis: transcription-initiation sites and domains of alpha genes.

1980 • 112 citations

Epstein-Barr virus RNA. VIII. Viral RNA in permissively infected B95-8 cells

1982 • 104 citations

Characterization of Herpes Simplex Virus Type 1 RNA Present in the Absence of De Novo Protein Synthesis

1980 • 101 citations

Temperature-sensitive mutants of herpes simplex virus type 1 defective in lysis but not in transformation

1975 • 100 citations

DNA-Binding Proteins of Cells Infected by Herpes Simplex Virus Type 1 and Type 2

1976 • 77 citations

Thermolabile in vivo DNA-binding activity associated with a protein encoded by mutants of herpes simplex virus type 1

1983 • 59 citations

Characterization of two conformational forms of the major DNA-binding protein encoded by herpes simplex virus 1

1982 • 58 citations

Characterization of a major late herpes simplex virus type 1 mRNA

1981 • 53 citations

Purification and molecular characterization of adenovirus type 2 DNA-binding protein

1977 • 39 citations

12 Herpes Simplex Viruses

1980 • 20 citations