Regulation of herpesvirus macromolecular synthesis. VIII. The transcription program consists of three phases during which both extent of transcription and accumulation of RNA in the cytoplasm are regulated

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

PLAQUE FORMATION AND ISOLATION OF PURE LINES WITH POLIOMYELITIS VIRUSES

1954 • 3,832 citations

Regulation of Herpesvirus Macromolecular Synthesis I. Cascade Regulation of the Synthesis of Three Groups of Viral Proteins

1974 • 1,479 citations

Characterization of Herpes Simplex Virus Strains Differing in their Effects on Social Behaviour of Infected Cells

1968 • 874 citations

Purification and Further Properties of Single‐Strand‐Specific Nuclease from Aspergillus oryzae

1973 • 862 citations

Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptides.

1975 • 616 citations

On the lability of poly(A) sequences during extraction of messenger RNA from polyribosomes

1972 • 566 citations

Proteins Specified by Herpes Simplex Virus V. Purification and Structural Proteins of the Herpesvirion

1972 • 565 citations

Isolation of mammalian messenger ribonucleic acid

1972 • 425 citations

Enzymatic Synthesis of Deoxyribonucleic Acid

1970 • 424 citations

Size, Composition, and Structure of the Deoxyribonucleic Acid of Herpes Simplex Virus Subtypes 1 and 2

1971 • 380 citations

Inverted Repetitions in the Chromosome of Herpes Simplex Virus

1974 • 357 citations

Anatomy of herpes simplex virus (HSV) DNA. X. Mapping of viral genes by analysis of polypeptides and functions specified by HSV-1 X HSV-2 recombinants

1978 • 339 citations

Anatomy of herpes simplex virus DNA: evidence for four populations of molecules that differ in the relative orientations of their long and short components.

1975 • 337 citations

Proteins Specified by Herpes Simplex Virus XI. Identification and Relative Molar Rates of Synthesis of Structural and Nonstructural Herpes Virus Polypeptides in the Infected Cell

1973 • 317 citations

The chromosome of bacteriophage T5

1972 • 289 citations

Temporal regulation of herpes simplex virus type 1 transcription: location of transcripts on the viral genome

1977 • 274 citations

Anatomy of herpes simplex virus DNA. II. Size, composition, and arrangement of inverted terminal repetitions

1975 • 265 citations

Regulation of herpesvirus macromolecular synthesis V. Properties of α polypeptides made in HSV-1 and HSV-2 infected cells

1977 • 253 citations

Physical mapping of herpes simplex virus-induced polypeptides

1978 • 248 citations

THE ISOLATION AND PROPERTIES OF A VARIANT OF HERPES SIMPLEX PRODUCING MULTINUCLEATED GIANT CELLS IN MONOLAYER CULTURES IN THE PRESENCE OF ANTIBODY1

1959 • 232 citations

Inhibitors of Protein Biosynthesis

1968 • 230 citations

STRUCTURAL BASIS FOR INHIBITION OF PROTEIN SYNTHESIS BY EMETINE AND CYCLOHEXIMIDE BASED ON AN ANALOGY BETWEEN IPECAC ALKALOIDS AND GLUTARIMIDE ANTIBIOTICS

1966 • 223 citations

Control of Protein Synthesis in Herpesvirus-infected Cells: Analysis of the Polypeptides Induced by Wild Type and Sixteen Temperature-sensitive Mutants of HSV strain 17

1976 • 211 citations

Anatomy of Herpes Simplex Virus DNA XII. Accumulation of Head-to-Tail Concatemers in Nuclei of Infected Cells and Their Role in the Generation of the Four Isomeric Arrangements of Viral DNA

1979 • 204 citations

Inhibition of DNA Polymerase from Herpes Simplex Virus-Infected Wi-38 Cells by Phosphonoacetic Acid

1975 • 174 citations

Anatomy of herpes simplex virus DNA: strain differences and heterogeneity in the locations of restriction endonuclease cleavage sites.

1975 • 165 citations

Anatomy of Herpes Simplex Virus DNA. IX. Apparent Exclusion of Some Parental DNA Arrangements in the Generation of Intertypic (HSV-1 × HSV-2) Recombinants

1977 • 163 citations

Herpes simplex virus resistance and sensitivity to phosphonoacetic acid

1977 • 156 citations

A Partial Denaturation Map of Herpes Simplex Virus Type 1 DNA: Evidence for Inversions of the Unique DNA Regions

1976 • 155 citations

Herpes simplex virus DNA

1968 • 148 citations

Inhibition of Herpes Simplex Virus Replication by Phosphonoacetic Acid

1974 • 148 citations

RNA synthesis in cells infected with herpes simplex virus. X. Properties of viral symmetric transcripts and of double-stranded RNA prepared from them

1975 • 111 citations

Preparation and characterization of highly radioactive in vitro labeled adenovirus DNA and DNA restriction fragments

1977 • 106 citations

Preparation of herpes simplex virus of high titer

1968 • 96 citations

Anatomy of herpes simplex virus DNA VII. alpha-RNA is homologous to noncontiguous sites in both the L and S components of viral DNA

1977 • 94 citations

Regulation of Herpesvirus Macromolecular Synthesis: Nuclear Retention of Nontranslated Viral RNA Sequences

1974 • 86 citations

Ribonucleic Acid Synthesis in Cells Infected with Herpes Simplex Virus: Controls of Transcription and of RNA Abundance

1972 • 72 citations

Regulation of Herpesvirus Macromolecular Synthesis: Evidence for Multilevel Regulation of Herpes Simplex 1 RNA and Protein Synthesis

1974 • 69 citations

Regulation of synthesis of herpes simplex type 1 virus mRNA during productive infection

1974 • 63 citations

The synthesis of herpes simplex virus proteins in the absence of virus DNA synthesis

1975 • 54 citations

A Temperature-sensitive Mutant of Herpes Simplex Virus Type 1 Defective in the Synthesis of the Major Capsid Polypeptide

1974 • 52 citations

Restricted transcription of the herpes simplex virus genome occurring early after infection and in the presence of metabolic inhibitors

1975 • 51 citations

Inhibitors of protein synthesis in eukaryotes: tools in cell research.

1973 • 50 citations

RNA synthesis in cells infected with herpes simplex virus. IX. Evidence for accumulation of abundant symmetric transcripts in nuclei

1975 • 49 citations

Transcription of the Herpes Simplex Virus Genome in Human Cells

1972 • 46 citations

Suppression of RNA precipitation during Cs2SO4 density gradient centrifugation

1966 • 42 citations

RNA SYNTHESIS IN CELLS INFECTED WITH HERPES SIMPLEX VIRUS, II. EVIDENCE THAT A CLASS OF VIRAL mRNA IS DERIVED FROM A HIGH MOLECULAR WEIGHT PRECURSOR SYNTHESIZED IN THE NUCLEUS

1969 • 37 citations

RNA Synthesis in Cells Infected with Herpes Simplex Virus VII. Control of Transcription and of Transcript Abundancies of Unique and Common Sequences of Herpes Simplex Virus 1 and 2

1973 • 30 citations

RNA synthesis in cells infected with herpes simplex virus. XII. Sequence complexity and properties of RNA differing in extent of adenylation

1976 • 30 citations

Evidence for transcriptional control of the herpes simplex virus genome in infected human cells

1972 • 29 citations

Relationship Between Post-Transcriptional Adenylation of Herpes Virus RNA and Messenger RNA Abundance

1973 • 26 citations

Ribonucleic Acid Synthesis in Cells Infected with Herpes Simplex Virus: Characterization of Viral High Molecular Weight Nuclear RNA

1975 • 21 citations

Mapping early transcripts of herpes simplex virus type 1 by electron microscopy

1978 • 20 citations

Regulation of herpesvirus macromolecular synthesis. VI. Synthesis and modification of viral polypeptides in enucleated cells

1977 • 20 citations

Symmetrical transcription of herpes simplex virus DNA in infected BSC-1 cells

1975 • 12 citations

RNA and Protein Synthesis in Herpesvirus-Infected Cells

1977 • 6 citations