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Calcium is essential for both the membrane binding and lytic activity of pore-forming protein (perforin) from cytotoxic T-lymphocyte

Data up to Jan 2025

Published1990
Citations30
References18

Total Citations Per Year

Abstract

References (18)

Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules.

1985 • 398 citations

A family of serine esterases in lytic granules of cytolytic T lymphocytes

1987 • 393 citations

Cytolytic T cell granules. Isolation, structural, biochemical, and functional characterization.

1984 • 329 citations

Mononuclear cells in myopathies: Quantitation of functionally distinct subsets, recognition of antigen-specific cell-mediated cytotoxicity in some diseases, and implications for the pathogenesis of the different inflammatory myopathies

1986 • 290 citations

The Ninth Component of Complement and the Pore-Forming Protein (Perforin 1) from Cytotoxic T Cells: Structural, Immunological, and Functional Similarities

1986 • 272 citations

Homology of perforin to the ninth component of complement (C9)

1988 • 268 citations

Cell-mediated killing: A common mechanism?

1986 • 114 citations

Liposomes as targets for granule cytolysin from cytotoxic large granular lymphocyte tumors.

1984 • 95 citations

Are proteinases functional molecules of T lymphocytes?

1987 • 74 citations

Dissociation of membrane binding and lytic activities of the lymphocyte pore-forming protein (perforin).

1987 • 73 citations

Intracellular proteolysis

1999 • 62 citations

Role of granule proteins in lymphocyte‐mediated killing

1986 • 37 citations

A C9 related channel forming protein in the cytoplasmic granules of human large granular lymphocytes

1985 • 21 citations

Proposed classification of leukocyte- associated cytolytic molecules

1987 • 18 citations

Effects of Heparin and Other Acid Mucopolysaccharides on the Activity of a Cytolytic Pore-Forming Protein (Perforin) from Cytotoxic T-Lymphocytes1

1988 • 5 citations

Isolation of a Ca-Dependent Erythrolytic Protein (Perforin) from Cytotoxic T-Lymphocytes

1987 • 4 citations

[Cytotoxic molecules, perforin and serine esterase in cytotoxic T lymphocyte].

1989 • 2 citations

Localization of BLT serine esterase is distinct from that of perforin in cytotoxic T lymphocyte.

1988 • 1 citations

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Calcium is essential for both the membrane binding and lytic activity of pore-forming… (1990) – Molecular Immunology | Metascience Observatory Explorer