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Administration of fenfluramine at different ambient temperatures produces different core temperature and 5-HT neurotoxicity profiles

Data up to Jan 2025

Published1997
Citations31
References31

Total Citations Per Year

Abstract

References (31)

Amphetamine: Effects on Catecholamine Systems and Behavior

1993 • 826 citations

A rapid method for the regional dissection of the rat brain

1980 • 540 citations

Further studies of the role of hyperthermia in methamphetamine neurotoxicity.

1994 • 401 citations

Environment-, drug- and stress-induced alterations in body temperature affect the neurotoxicity of substituted amphetamines in the C57BL/6J mouse.

1994 • 254 citations

The influence of environmental temperature on the transient effects of methamphetamine on dopamine levels and dopamine release in rat striatum.

1992 • 231 citations

Effects of 3,4-methylenedioxymethamphetamine on autonomic thermoregulatory responses of the rat

1991 • 222 citations

The substituted amphetamines 3,4-methylenedioxymethamphetamine, methamphetamine, p-chloroamphetamine and fenfluramine induce 5-hydroxytryptamine release via a common mechanism blocked by fluoxetine and cocaine

1992 • 209 citations

Co-administration of MDMA with drugs that protect against MDMA neurotoxicity produces different effects on body temperature in the rat.

1996 • 147 citations

Anatomic evidence for a neurotoxic effect of (±)-fenfluramine upon serotonergic projections in the rat

1990 • 121 citations

Effect of ambient temperature on hyperthermia and hyperkinesis induced by 3,4-methylenedioxymethamphetamine (MDMA or “ecstasy”) in rats

1994 • 111 citations

Effects of repeated fenfluramine administration on indices of monoamine function in rat brain: pharmacokinetic, dose response, regional specificity and time course data.

1990 • 109 citations

Effects of a cold environment or age on methamphetamine-induced dopamine release in the caudate putamen of female rats

1993 • 106 citations

Role of hypothermia in the mechanism of protection against serotonergic toxicity. II. Experiments with methamphetamine, p-chloroamphetamine, fenfluramine, dizocilpine and dextromethorphan.

1995 • 94 citations

The effects of D-amphetamine and related drugs on colonic temperatures of rats kept at various ambient temperatures

1972 • 93 citations

The role of temperature, stress, and other factors in the neurotoxicity of the substituted amphetamines 3,4-methylenedioxymethamphetamine and fenfluramine

1995 • 93 citations

3,4-Methylenedioxyamphetamine (MDA) analogues exhibit differential effects on synaptosomal release of 3H-dopamine and 3H-5-hydroxytryptamine

1991 • 91 citations

Long-term effects of fenfluramine on central serotonergic mechanisms

1979 • 78 citations

Species differences in the kinetics and metabolism of fenfluramine isomers.

1982 • 68 citations

Fenfluramine: neurotoxicity.

1986 • 68 citations

Effect of depletion of brain serotonin by repeated fenfluramine on neurochemical and anorectic effects of acute fenfluramine.

1988 • 64 citations

Determination of dopamine norepinephrine, serotonin and their major metabolic products in rat brain by reverse-phase ion-pair high performance liquod chromatography with electrochemical detection

1985 • 62 citations

Hyperthermia Induced by Amphetamine, p-Chloroamphetamine and Fenfluramine in the Rat

1975 • 51 citations

Effects of Fenfluramine and Norfenfluramine on Brain Serotonin Metabolism in Rats

1978 • 49 citations

Report on the NIH Workshop on Pharmacologic Treatment of Obesity

1994 • 48 citations

Antagonism of fenfluramine‐induced hyperthermia in rats by some, but not all, selective inhibitors of 5‐hydroxytryptamine uptake

1984 • 22 citations

Fenfluramine's appetite suppression and serotonin neurotoxicity are separable

1995 • 15 citations

Interaction of fenfluramine with d-amphetamine-induced excitatory behaviour and hyperthermia

1972 • 15 citations

Ambient temperature modulation of fenfluramine-induced thermogenesis in the rat

1990 • 14 citations

Fenfluramine and body temperature

1969 • 10 citations

New Evidence for a Loss of Serotonergic Nerve Terminals in Rats Treated with d,l‐Fenfluramine

1993 • 9 citations

Disparate effects of fenfluramine on thermogenesis in brown adipose tissue in the rat

1992 • 6 citations

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Administration of fenfluramine at different ambient temperatures produces different core… (1997) – Brain Research | Metascience Observatory Explorer