New Evidence for a Loss of Serotonergic Nerve Terminals in Rats Treated with d,l‐Fenfluramine

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

1978 • 6,494 citations

A rapid method for preparing synaptosomes: Comparison, with alternative procedures

1981 • 392 citations

Fenfluramine

1975 • 210 citations

Serotonergic Responsivity in Male Young Adults With Autistic Disorder

1989 • 206 citations

Autism: Review of neurochemical investigation

1990 • 188 citations

Action of fenfluramine on monoamine stores of rat tissues

1971 • 185 citations

Mechanisms of effects of d-Fenfluramine on brain serotonin metabolism in rats: Uptake inhibition versus release

1988 • 157 citations

Effects of repeated fenfluramine administration on indices of monoamine function in rat brain: pharmacokinetic, dose response, regional specificity and time course data.

1990 • 109 citations

5-Hydroxytryptamine uptake blockers attenuate the 5-hydroxytryptamine-releasing effect of 3,4-methylenedioxymethamphetamine and related agents

1990 • 106 citations

Distribution of Specific High‐Affinity Binding Sites for [³H]Imipramine in Human Brain

1981 • 104 citations

High affinity binding of3H-paroxetine and3H-imipramine to rat neuronal membranes

1986 • 98 citations

Optimization of freezing, storage, and thawing conditions for the preparation of metabolically active synaptosomes from frozen rat and human brain

1986 • 90 citations

Fenfluramine selectively and differentially decreases the density of serotonergic nerve terminals in rat brain: evidence from immunocytochemical studies.

1989 • 82 citations

Long-term effects of fenfluramine on central serotonergic mechanisms

1979 • 78 citations

Radioligand—receptor binding studies: what's wrong with the scatchard analysis?

1984 • 71 citations

Fenfluramine: neurotoxicity.

1986 • 68 citations

Effect of depletion of brain serotonin by repeated fenfluramine on neurochemical and anorectic effects of acute fenfluramine.

1988 • 64 citations

Anorexigene Phenylalkylamine und Serotoninstoffwechsel

1967 • 64 citations

Effect of d-fenfluramine on serotonin release in brains of anaesthetized rats

1989 • 63 citations

Comparison between the neurotoxic and serotonin-depleting effects of various halogenated derivatives of amphetamine in the rat.

1977 • 61 citations

Effects of high‐dose fenfluramine treatment on monoamine uptake sites in rat brain: Assessment using quantitative autoradiography

1990 • 59 citations

Fenfluramine: Long-term reduction in brain serotonin (5-hydroxytryptamine)

1976 • 55 citations

Pharmacokinetics of fenfluramine and norfenfluramine in volunteers given d- and dl-fenfluramine for 15 days

1985 • 50 citations

Effects of fluoxetine ord-fenfluramine on serotonin release from, and levels in, rat frontal cortex

1990 • 50 citations

Comparative serotonin neurotoxicity of the stereoisomers of fenfluramine and norfenfluramine

1990 • 50 citations

Immunohistochemical study of short- and long-term effects ofdl-fenfluramine on the serotonergic innervation of the rat hippocampal formation

1991 • 41 citations

FENFLURAMINE TREATMENT OF AUTISM

1988 • 41 citations

Reversible, short-lasting, and dose-dependent effect of (+)-fenfluramine on neocortical serotonergic axons

1991 • 38 citations

In Vitro and In Vivo Irreversible Blockade of Cortical S₂ Serotonin Receptors by N‐Ethoxycarbonyl‐2‐Ethoxy‐1,2‐Dihydroquinoline: A Technique for Investigating S₂ Serotonin Receptor Recovery

1986 • 30 citations

Evidence for the existence of at least two different binding sites for 5HT-reuptake inhibitors within the 5HT-reuptake system from human platelets

1988 • 26 citations

Evidence against a neurotoxic action of halogenated amphetamines on serotoninergic B9 cells. A morphometric fluorescence histochemical study

1978 • 24 citations

Lack of morphological changes in the neurons of the B-9 group in rats treated with fenfluramine

1979 • 22 citations

Interconversion into a low active state protects vascular 5-HT2-receptors against irreversible antagonism by phenoxybenzamine

1987 • 16 citations

Neuropathology & pathogenesis of experimental fenfluramine toxicity in young rodents.

1990 • 5 citations