Estrogen Up-regulates Apolipoprotein E (ApoE) Gene Expression by Increasing ApoE mRNA in the Translating Pool via the Estrogen Receptor α-Mediated Pathway

Cloning of a novel receptor expressed in rat prostate and ovary.

1996 • 4,782 citations

Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology

1988 • 3,984 citations

ERβ: Identification and characterization of a novel human estrogen receptor

1996 • 2,262 citations

Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene.

1993 • 1,836 citations

Magnesium precipitation of ribonucleoprotein complexes. Expedient techniques for the isolation of undegraded polysomes and messenger ribonucleic acid

1974 • 987 citations

Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor.

1988 • 947 citations

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells.

1992 • 897 citations

Cloning, Chromosomal Localization, and Functional Analysis of the Murine Estrogen Receptor β

1997 • 862 citations

The LDL–receptor–related protein, LRP, is an apolipoprotein E-binding protein

1989 • 680 citations

Abnormal lipoprotein receptor-binding activity of the human E apoprotein due to cysteine-arginine interchange at a single site.

1982 • 674 citations

Estrogen inhibits the vascular injury response in estrogen receptor α-deficient mice

1997 • 499 citations

Enhanced binding by cultured human fibroblasts of apo-E-containing lipoproteins as compared with low density lipoproteins

1978 • 430 citations

Activation and Entrainment Mapping Defines the Tricuspid Annulus as the Anterior Barrier in Typical Atrial Flutter

1996 • 343 citations

The Effects of Estrogen Administration on Plasma Lipoprotein Metabolism in Premenopausal Females

1983 • 340 citations

Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene

1993 • 315 citations

Estrogen Receptor-β mRNA Expression in Rat Ovary: Down-Regulation by Gonadotropins

1997 • 312 citations

Vascular estrogen receptors and endothelium-derived nitric oxide production in the mouse aorta. Gender difference and effect of estrogen receptor gene disruption.

1997 • 269 citations

Estrogen reduces atherosclerotic lesion development in apolipoprotein E-deficient mice.

1996 • 248 citations

Apolipoprotein E Produced by Human Monocyte-derived Macrophages Mediates Cholesterol Efflux That Occurs in the Absence of Added Cholesterol Acceptors

1996 • 147 citations

Overexpression of apolipoprotein E in transgenic mice: marked reduction in plasma lipoproteins except high density lipoprotein and resistance against diet-induced hypercholesterolemia.

1992 • 145 citations

Lipoprotein binding and endosomal itinerary of the low density lipoprotein receptor-related protein in rat liver.

1989 • 112 citations

Effects of estrogen replacement on plasma lipoproteins and apolipoproteins in postmenopausal, dyslipidemic women

1992 • 105 citations

A polymorphism affecting apolipoprotein A-II translational efficiency determines high density lipoprotein size and composition.

1990 • 103 citations

Evolution of apolipoprotein E: mouse sequence and evidence for an 11-nucleotide ancestral unit.

1985 • 92 citations

Influence of development, estrogens, and food intake on apolipoprotein A-I, A-II, and E mRNA in rat liver and intestine.

1989 • 90 citations

Apolipoprotein E gene expression in various tissues of mouse and regulation by estrogen.

1996 • 88 citations

In vivo regulation of low‐density lipoprotein receptors by estrogen differs at the post‐transcriptional level in rat and mouse

1993 • 82 citations

Differential effects of estrogen on low-density lipoprotein subclasses in healthy postmenopausal women

1993 • 79 citations

Effects of an atherogenic diet on apolipoprotein E biosynthesis in the rat

1981 • 78 citations

Apolipoprotein E gene mapping and expression: localization of the structural gene to human chromosome 19 and expression of ApoE mRNA in lipoprotein- and non-lipoprotein-producing tissues

1985 • 70 citations

Regulation of hepatic apolipoprotein synthesis in the 17 alpha-ethinyl estradiol-treated rat.

1991 • 61 citations

Effect of Sucrose Diet on Apolipoprotein Biosynthesis in Rat Liver

1989 • 61 citations

Dietary fatty acids and dietary cholesterol differ in their effect on the in vivo regulation of apolipoprotein A-I and A-II gene expression in inbred strains of mice

1992 • 50 citations

Post-translational regulation of macrophage apoprotein E production.

1992 • 50 citations

In vivo regulation of apolipoprotein A-I gene expression by estradiol and testosterone occurs by different mechanisms in inbred strains of mice.

1991 • 48 citations

Effects of ethynyl estradiol on serum lipoprotein lipids in male and female rats

1978 • 44 citations

Cap binding complexes and cellular growth control

1995 • 34 citations

Hormonal and nutritional stimuli modulate apolipoprotein B mRNA editing in mouse liver

1992 • 33 citations

Hepatic polysomes that contain apoprotein B mRNA have unusual physical properties.

1993 • 31 citations

Actions of oestrogen on vascular endothelial and smooth-muscle cells

1997 • 29 citations

Regulation of the apolipoprotein E by dietary lipids occurs by transcriptional and post-transcriptional mechanisms

1996 • 29 citations

Expression of LDL receptor, apolipoprotein B, apolipoprotein A-I and apolipoprotein A-IV mRNA in various mouse organs as determined by a novel RNA-excess solution hybridization assay

1991 • 28 citations

Regulation of lipoprotein metabolism by estrogen in inbred strains of mice occurs primarily by posttranscriptional mechanisms.

1997 • 27 citations

Quantification of apolipoproteins in rat serum and in cultured rat hepatocytes by enzyme-linked immunosorbent assay

1986 • 25 citations

Use of riboprobes for northern blotting analysis.

1991 • 19 citations

Hormonal regulation of human apolipoprotein E gene expression in HepG2 cells

1993 • 19 citations

Oestrogens as antioxidant cardioprotectants

1997 • 16 citations

Increased apoB100 mRNA in Inbred Strains of Mice by Estrogen Is Caused by Decreased RNA Editing Protein mRNA

1995 • 14 citations

Translational control of ornithine-δ-aminotransferase (OAT) by estrogen

1993 • 12 citations