Mutual Stabilization of V_Land V_Hin Single-Chain Antibody Fragments, Investigated with Mutants Engineered for Stability

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

1986 • 6,284 citations

Protein structure: A practical approach

1990 • 2,071 citations

Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme

1996 • 490 citations

Sequence Statistics Reliably Predict Stabilizing Mutations in a Protein Domain

1994 • 338 citations

Antibody scFv fragments without disulfide bonds, made by molecular evolution 1 1Edited by I. A. Wilson

1998 • 240 citations

‘Camelising’ human antibody fragments: NMR studies on VH domains

1994 • 149 citations

A natural antibody missing a cysteine in VH: consequences for thermodynamic stability and folding

1997 • 127 citations

ANTIBODY ENGINEERING

1997 • 105 citations

Characterization of the linker peptide of the single‐chain F_v fragment of an antibody by NMR spectroscopy

1993 • 82 citations

Expressing Antibodies in Escherichia coli

1995 • 29 citations

Prospects for genetic diagnosis of inherited predisposition to cancer

1990 • 28 citations

Effects of substitutions of amino acids on the thermal stability of the Fv fragments of antibodies

1994 • 27 citations

Comparison of the amide proton exchange behavior of the rapidly formed folding intermediate and the native state of an antibody scFv fragment

1997 • 22 citations

From the National Institutes of Health

1992 • 11 citations