A Novel Clinically Relevant Approach to Tip the Balance Toward Regulation in Stringent Transplant Model

Regulatory T cells mediate maternal tolerance to the fetus

2004 • 1,568 citations

Foxp3⁺CD25⁺CD4⁺ natural regulatory T cells in dominant self‐tolerance and autoimmune disease

2006 • 1,535 citations

Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells

2005 • 1,090 citations

Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell Programs

2008 • 1,088 citations

Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance

1999 • 762 citations

Cutting Edge: Regulatory T Cells Induce CD4+CD25−Foxp3− T Cells or Are Self-Induced to Become Th17 Cells in the Absence of Exogenous TGF-β

2007 • 704 citations

Homeostasis and anergy of CD4+CD25+ suppressor T cells in vivo

2001 • 658 citations

The lifestyle of naturally occurring CD4⁺CD25⁺Foxp3⁺ regulatory T cells

2006 • 589 citations

Cd4+Cd25+ Immune Regulatory Cells Are Required for Induction of Tolerance to Alloantigen via Costimulatory Blockade

2001 • 580 citations

Mechanisms of action of antithymocyte globulin: T-cell depletion and beyond

2007 • 539 citations

Prevention of acute and chronic allograft rejection with CD4+CD25+Foxp3+ regulatory T lymphocytes

2007 • 502 citations

Heterogeneity of natural Foxp3 ⁺ T cells: A committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity

2009 • 493 citations

Homeostatic proliferation is a barrier to transplantation tolerance

2003 • 403 citations

A Novel Mechanism of Action for Anti-Thymocyte Globulin

2006 • 365 citations

Protective Conditioning for Acute Graft-versus-Host Disease

2005 • 324 citations

Contrasting Effects of Cyclosporine and Rapamycin in De Novo Generation of Alloantigen-Specific Regulatory T Cells

2007 • 258 citations

Regulatory T cells in virus infections

2006 • 254 citations

Induction of Fas (Apo-1, CD95)-Mediated Apoptosis of Activated Lymphocytes by Polyclonal Antithymocyte Globulins

1998 • 212 citations

ANTIBODIES AGAINST FUNCTIONAL LEUKOCYTE SURFACE MOLECULES IN POLYCLONAL ANTILYMPHOCYTE AND ANTITHYMOCYTE GLOBULINS

1991 • 203 citations

CD4+CD25+Regulatory T Cells in Transplantation: Progress, Challenges and Prospects

2007 • 186 citations

Cutting Edge: Foxp3-Mediated Induction of Pim 2 Allows Human T Regulatory Cells to Preferentially Expand in Rapamycin

2008 • 180 citations

Cutting Edge: CD4+CD25+ Alloantigen-Specific Immunoregulatory Cells That Can Prevent CD8+ T Cell-Mediated Graft Rejection: Implications for Anti-CD154 Immunotherapy

2002 • 177 citations

A COMPREHENSIVE DEFINITION OF THE MAJOR ANTIBODY SPECIFICITIES IN POLYCLONAL RABBIT ANTITHYMOCYTE GLOBULIN1

1994 • 167 citations

COMPARATIVE POLYCLONAL ANTITHYMOCYTE GLOBULIN AND ANTILYMPHOCYTE/ANTILYMPHOBLAST GLOBULIN ANTI-CD ANTIGEN ANALYSIS BY FLOW CYTOMETRY

1995 • 166 citations

COMPARATIVE POLYCLONAL ANTITHYMOCYTE GLOBULIN AND ANTILYMPHOCYTE/ANTILYMPHOBLAST GLOBULIN ANTI-CD ANTIGEN ANALYSIS BY FLOW CYTOMETRY

1995 • 166 citations

Achieving Donor-Specific Hyporesponsiveness Is Associated with FOXP3+ Regulatory T Cell Recruitment in Human Renal Allograft Infiltrates

2007 • 158 citations

A New Look at Blockade of T-cell Costimulation: A Therapeutic Strategy for Long-term Maintenance Immunosuppression

2006 • 142 citations

Accelerated Memory Cell Homeostasis during T Cell Depletion and Approaches to Overcome It

2006 • 139 citations

Antigen-specific precursor frequency impacts T cell proliferation, differentiation, and requirement for costimulation

2007 • 126 citations

Control of Memory CD4 T Cell Recall by the CD28/B7 Costimulatory Pathway

2006 • 124 citations

Memory T Cells in Transplantation: Generation, Function, and Potential Role in Rejection

2004 • 121 citations

The balance of deletion and regulation in allograft tolerance

2003 • 108 citations

CD4+ Regulatory T Cells Are Spared from Deletion by Antilymphocyte Serum, a Polyclonal Anti-T Cell Antibody

2006 • 95 citations

Ex Vivo-Expanded Natural CD4+CD25+ Regulatory T Cells Synergize With Host T-Cell Depletion to Promote Long-Term Survival of Allografts

2008 • 92 citations

THE CLINICAL USE OF ANTILYMPHOCYTE GLOBULIN IN RENAL HOMOTRANSPLANTATION

1967 • 82 citations

Murine Antithymocyte Globulin Therapy Alters Disease Progression in NOD Mice by a Time-Dependent Induction of Immunoregulation

2007 • 77 citations

Targeting Acute Allograft Rejection by Immunotherapy With Ex Vivo-Expanded Natural CD4+CD25+ Regulatory T Cells

2006 • 62 citations

Induction of immunosuppression with polyclonal antithymocyte globulins: an overview.

2003 • 58 citations

A Role for CD28 in Lymphopenia-Induced Proliferation of CD4 T Cells

2004 • 57 citations

Allograft Rejection in a New Allospecific CD4+ TCR Transgenic Mouse

2003 • 54 citations

Characterization of in vitro antimurine thymocyte globulin–induced regulatory T cells that inhibit graft-versus-host disease in vivo

2007 • 44 citations

Dynamic regulation of FoxP3 expression controls the balance between CD4⁺ T cell activation and cell death

2005 • 41 citations

Strategies to Induce Marked Prolongation of Secondary Skin Allograft Survival in Alloantigen-Primed Mice

2008 • 32 citations

Tolerizing Effects of Co-stimulation Blockade Rest on Functional Dominance of CD4+CD25+ Regulatory T Cells

2005 • 25 citations

CTLA-4 Engagement and Regulatory CD4+CD25+ T Cells Independently Control CD8+-Mediated Responses under Costimulation Blockade

2006 • 17 citations

Rabbit Polyclonal Mouse Antithymocyte Globulin Administration Alters Dendritic Cell Profile and Function in NOD Mice to Suppress Diabetogenic Responses

2009 • 15 citations

Do Regulatory T Cells Play a Role in the Control of Homeostatic Proliferation?

2005 • 11 citations