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Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

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Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

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GROWTH FACTOR RECEPTOR TYROSINE KINASES

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Purification and characterization of a newly identified growth factor specific for epithelial cells.

1989 • 842 citations

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1986 • 793 citations

Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET.

1991 • 698 citations

Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells.

1990 • 695 citations

Clonal expansion of p53 mutant cells is associated with brain tumour progression

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Evidence for the identity of human scatter factor and human hepatocyte growth factor.

1991 • 651 citations

Transforming growth factor alpha may be a physiological regulator of liver regeneration by means of an autocrine mechanism.

1989 • 528 citations

A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor.

1991 • 502 citations

Influence of organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice.

1988 • 462 citations

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Cancer metastasis: tumor cell and host organ properties important in metastasis to specific secondary sites

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Clinical perspective of human colorectal cancer metastasis

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1988 • 365 citations

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1988 • 356 citations

Polypeptide Growth Factors: Roles In Normal And Abnormal Cell Growth

1987 • 339 citations

Metastatic Model for Human Prostate Cancer Using Orthotopic Implantation in Nude Mice

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Mechanisms of human tumor metastasis studied in patients with peritoneovenous shunts.

1984 • 301 citations

Expression of hepatocyte growth factor gene in endothelial and kupffer cells of damaged rat livers, as revealed by insitu hydridization

1990 • 299 citations

?Seed and soil? revisited: mechanisms of site-specific metastasis

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Hepatocyte growth factor inhibits growth of hepatocellular carcinoma cells.

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Epidermal growth factor and transforming growth factor α

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Metastatic behavior of tumor cells isolated from primary and metastatic human colorectal carcinomas implanted into different sites in nude mice.

1986 • 243 citations

Hepatocyte growth factor--scatter factor: mitogen, motogen, and met.

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Transforming growth factor alpha and beta expression in human colon cancer lines: implications for an autocrine model.

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The biology of cancer metastasis and implications for therapy

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Orthotopic implantation of human colon carcinomas into nude mice provides a valuable model for the biology and therapy of metastasis

1991 • 181 citations

Growth Dominance of the Metastatic Cancer Cell: Cellular and Molecular Aspects

1990 • 179 citations

Localization of hepatocyte growth factor in human and rat tissues: An immunohistochemical study

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Formation of metastasis by human breast carcinoma cells (MCF-7) in nude mice

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Evidence for the identy of human scatter factor and human hepatocyte growth factor.

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Novel intrapulmonary model for orthotopic propagation of human lung cancers in athymic nude mice.

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Transfer of motogenic and invasive response to scatter factor/hepatocyte growth factor by transfection of human MET protooncogene.

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Cancer Progression and Growth: Relationship of Paracrine and Autocrine Growth Mechanisms to Organ Preference of Metastasis

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Experimental Nude Mouse Model of Human Colorectal Cancer Liver Metastases<xref ref-type="fn" rid="FN2">2</xref>

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Growth stimulation by coexpression of transforming growth factor-alpha and epidermal growth factor-receptor in normal and adenomatous human colon epithelium.

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Intravenous but not intragastric urogastrone-EGF is trophic to the intestine of parenterally fed rats.

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Expression of the Transforming Growth Factor-α/Epidermal Growth Factor Receptor Pathway in Normal Human Breast Epithelial Cells

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Expression of transforming growth factor alpha messenger rna in the normal and neoplastic gastro‐intestinal tract

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Growth-Regulatory Factors for Normal, Premalignant, and Malignant Human Cells In Vitro

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Separable growth and migration factors for large-cell lymphoma cells secreted by microvascular endothelial cells derived from target organs for metastasis

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ON THE CAUSE OF THE LOCALIZATION OF SECONDARY TUMORS AT POINTS OF INJURY

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A rapid colorimetric in situ messenger RNA hybridization technique for analysis of epidermal growth factor receptor in paraffin-embedded surgical specimens of human colon carcinomas.

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Susceptibility of Injured Tissues to Hematogenous Metastases

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Fibroblasts are critical determinants in prostatic cancer growth and dissemination

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Transforming growth factor receptors in liver regeneration following partial hepatectomy in the rat.

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Enhanced growth of tumour cells in healing colonie anastomoses and laparotomy wounds

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A rapid colorimetric in situ mRNA hybridization technique using hyperbiotinylated oligonucleotide probes for analysis of mdr1 in mouse colon carcinoma cells.

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Enhanced Tumorigenicity, Melanogenesis, and Metastases of a Human Malignant Melanoma After Subdermal Implantation in Nude Mice

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Automated Molecular Pathology : One Hour In Situ DNA Hybridization

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Increased expression of the epidermal growth factor receptor on human colon carcinoma cells

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Trauma as a Cause of Localization of Blood-Borne Metastases

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Proto-oncogene expression and growth factors during liver regeneration.

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The Development of Blood-Borne Metastases

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Growth factors and their receptors in metastasis.

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EXPERIMENTAL STUDY OF FACTORS INFLUENCING DEVELOPMENT OF HEPATIC METASTASES FROM CIRCULATING TUMOR CELLS.

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Organ distribution of experimental metastases of a human colorectal carcinoma injected in nude mice

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Facilitation by partial hepatectomy of tumor growth within the rat liver following intraportal injection of syngeneic tumor cells

1991 • 39 citations

Expression level of the nm23 gene in clonal populations of metastatic murine and human neoplasms.

1992 • 38 citations

Increased Expression of the Epidermal Growth Factor Receptor on Human Colon Carcinoma Cells

1986 • 38 citations

Pattern of spread of bloodborne tumour

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The use of molecular genetic markers to demonstrate the effect of organ environment on clonal dominance in a human renal‐cell carcinoma grown in nude mice

1992 • 31 citations

The biology of colorectal carcinoma

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Modulation of a high molecular weight form of transforming growth factor-α in human colon carcinoma cell lines

1988 • 28 citations

Colorimetric detection of herpes simplex virus by DNA insitusandwich hybridization: a rapid, formamide-free, random oligomer-enhanced method

1992 • 26 citations

Expression of multi-cytokine resistance and multi-growth factor independence in advanced stage metastatic cancer. Malignant melanoma as a paradigm.

1992 • 26 citations

Brain acetylcholinesterase after acute parathion poisoning: A comparative quantitative histochemical analysis post mortem

1988 • 24 citations

Effect of partial hepatectomy on experimental liver invasion by intraportally injected colon carcinoma cells in rats.

1988 • 23 citations

Altered establishment/clearance mechanisms during experimental micrometastasis with live and/or disabled bacterial lacZ-tagged tumor cells.

1992 • 21 citations

Clonal diversity of the Kirsten-ras oncogene during tumor progression in athymic nude mice: mechanisms of amplification and rearrangement.

1988 • 20 citations

High-resolution analyses of two different classes of tumor cells in situ tagged with alternative histochemical marker genes.

1992 • 19 citations

Clonal dominance of select subsets of viral kirsten ras⁺‐transformed 3T3 cells during tumor progression

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Adhesion of Kirsten-ras+ tumor-progressing and Kirsten-ras- revertant 3T3 cells on fibronectin proteolytic fragments.

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Hepatocyte growth factor—How do I know thee? Let me count the ways

1992 • 11 citations

Critical molecular determinants of carcinogenesis

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Preferential growth stimulation of metastatic rat mammary adenocarcinoma cells by organ-derived syngeneic fibroblasts in vitro.

1992 • 5 citations

Foreword

1992 • 5 citations

Extracellular Matrix Interactions with Tumor-Progressing Cells: Tumor versus Cell Type-Specific Mechanisms

1991 • 3 citations