Large differences in the helix propensities of alanine and glycine

Determination of the helix and β form of proteins in aqueous solution by circular dichroism

1974 • 2,040 citations

Theory of the Phase Transition between Helix and Random Coil in Polypeptide Chains

1959 • 1,756 citations

Biophysical chemistry

1979 • 1,709 citations

A Thermodynamic Scale for the Helix-Forming Tendencies of the Commonly Occurring Amino Acids

1990 • 1,173 citations

On the Theory of Helix—Coil Transition in Polypeptides

1961 • 785 citations

Unusually stable helix formation in short alanine-based peptides.

1989 • 752 citations

Theory of helix-coil transitions in biopolymers

1970 • 734 citations

Tests of the helix dipole model for stabilization of α-helices

1987 • 598 citations

Relative helix-forming tendencies of nonpolar amino acids

1990 • 455 citations

Side Chain Contributions to the Stability of Alpha-Helical Structure in Peptides

1990 • 455 citations

Conformational energy estimates for statistically coiling polypeptide chains

1967 • 349 citations

Helix-coil stability constants for the naturally occurring amino acids in water. 22. Histidine parameters from random poly[(hydroxybutyl)glutamine-co-L-histidine]

1984 • 162 citations

Effect of central-residue replacements on the helical stability of a monomeric peptide

1990 • 122 citations

The stabilization of the α‐helix in aqueous solution by hydrophobic side‐chain interaction

1966 • 102 citations

Molecular Theory of the Helix–Coil Transition in Polyamino Acids. III. Evaluation and Analysis of s and σ for Polyglycine and Poly-<scp>l</scp>-alanine in Water

1971 • 58 citations

Effect of the substitution Ala .fwdarw. Gly at each of five residue positions in the C-peptide helix

1989 • 55 citations

Effect of side chain-backbone electrostatic interactions on the stability of alpha-helices.

1985 • 39 citations

Helix‐coil stability constants for the naturally occurring amino acids in water. XXIII. Proline parameters from random poly(hydroxybutylglutamine‐<scp>CO</scp>‐<scp>L</scp>‐proline)

1990 • 36 citations