Structural mimicry of DH domains by Arfaptin suggests a model for the recognition of Rac–GDP by its guanine nucleotide exchange factors

Small GTP-Binding Proteins

2001 • 2,449 citations

Structural Basis for Activation of ARF GTPase

1998 • 534 citations

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins

1994 • 518 citations

The Dbl family of oncogenes

1996 • 497 citations

Structural Basis for Relief of Autoinhibition of the Dbl Homology Domain of Proto-Oncogene Vav by Tyrosine Phosphorylation

2000 • 381 citations

Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1

2000 • 356 citations

GEFs: structural basis for their activation of small GTP-binding proteins

1999 • 334 citations

Structure of the TPR Domain of p67phox in Complex with Rac·GTP

2000 • 300 citations

The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways

2001 • 251 citations

A role for POR1, a Rac1-interacting protein, in ARF6-mediated cytoskeletal rearrangements

1997 • 234 citations

The Kinetic Mechanism of Ran-Nucleotide Exchange Catalyzed by RCC1

1995 • 224 citations

Kinetic Analysis by Fluorescence of the Interaction between Ras and the Catalytic Domain of the Guanine Nucleotide Exchange Factor Cdc25^Mm

1998 • 221 citations

Crystal Structure of the Dbl and Pleckstrin Homology Domains from the Human Son of Sevenless Protein

1998 • 220 citations

The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue

1997 • 192 citations

Identification of a novel Rac1-interacting protein involved in membrane ruffling.

1996 • 171 citations

NMR Structure and Mutagenesis of the N-Terminal Dbl Homology Domain of the Nucleotide Exchange Factor Trio

1998 • 171 citations

Modulation of Host Signaling by a Bacterial Mimic

2000 • 170 citations

GEFs, GAPs, GDIs and effectors: taking a closer (3D) look at the regulation of Ras-related GTP-binding proteins

1997 • 168 citations

Structure and mutagenesis of the Dbl homology domain

1998 • 142 citations

Crystal Structure of the Rac1−RhoGDI Complex Involved in NADPH Oxidase Activation^,

2001 • 135 citations

The structural GDP/GTP cycle of human Arf6

2001 • 123 citations

Structure-based Mutagenesis Reveals Distinct Functions for Ras Switch 1 and Switch 2 in Sos-catalyzed Guanine Nucleotide Exchange

2001 • 122 citations

How the Pseudomonas aeruginosa ExoS toxin downregulates Rac.

2001 • 116 citations

Arfaptin 1, a Putative Cytosolic Target Protein of ADP-ribosylation Factor, Is Recruited to Golgi Membranes

1997 • 112 citations

Differential Binding of Arfaptin 2/POR1 to ADP-Ribosylation Factors and Rac1

2001 • 54 citations

Effects of Arfaptin 1 on Guanine Nucleotide-dependent Activation of Phospholipase D and Cholera Toxin by ADP-ribosylation Factor

1998 • 27 citations

Structure of the small G protein Rap2 in a non-catalytic complex with GTP

1999 • 23 citations

Sequence and 3D structural relationships between mammalian Ras‐ and Rho‐specific GTPase‐activating proteins (GAPs): the cradle fold

1998 • 16 citations