Induction of the multispecific organic anion transporter (cMoat/mrp2) gene and biliary glutathione secretion by the herbicide 2,4,5-trichlorophenoxyacetic acid in the mouse liver

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

[70] Determination of glutathione and glutathione disulfide in biological samples

1985 • 2,678 citations

Growth of human hepatoma cells lines with differentiated functions in chemically defined medium.

1982 • 1,367 citations

Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line

1979 • 1,305 citations

Congenital Jaundice in Rats with a Mutation in a Multidrug Resistance-Associated Protein Gene

1996 • 827 citations

cDNA Cloning of the Hepatocyte Canalicular Isoform of the Multidrug Resistance Protein, cMrp, Reveals a Novel Conjugate Export Pump Deficient in Hyperbilirubinemic Mutant Rats

1996 • 641 citations

A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome

1997 • 551 citations

CHRONIC IDIOPATHIC JAUNDICE WITH UNIDENTIFIED PIGMENT IN LIVER CELLS

1954 • 442 citations

Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport

1995 • 385 citations

Molecular aspects of hepatobiliary transport

1997 • 304 citations

ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2

1997 • 300 citations

Molecular cloning of canalicular multispecific organic anion transporter defective in EHBR

1997 • 294 citations

Expression and localization of the conjugate export pump encoded by the MRP2 (cMRP/cMOAJ) gene in liver

1997 • 269 citations

Coordinated Induction of / Pump and γ-Glutamylcysteine Synthetase by Heavy Metals in Human Leukemia Cells

1996 • 264 citations

Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione

1999 • 246 citations

Fatty acid oxidation by human liver peroxisomes

1979 • 197 citations

Hepatobiliary transport of glutathione and glutathione conjugate in rats with hereditary hyperbilirubinemia.

1989 • 172 citations

Tumor Necrosis Factor Increases Hepatocellular Glutathione by Transcriptional Regulation of the Heavy Subunit Chain of γ-Glutamylcysteine Synthetase

1997 • 145 citations

Fibrates induce mdr2 gene expression and biliary phospholipid secretion in the mouse

1996 • 144 citations

The role of the canalicular multispecific organic anion transporter in the disposal of endo-and xenobiotics

1994 • 106 citations

Rapid oxidation in vitro of endogenous and exogenous glutathione in bile of rats.

1981 • 96 citations

Sequence Analysis and Functional Characterization of the 5′-Flanking Region of the Rat Multidrug Resistance Protein 2 (MRP2) Gene

1998 • 92 citations

Induction ofcMrp/cMoat gene expression by cisplatin, 2- acetylaminofluorene, or cycloheximide in rat hepatocytes

1997 • 90 citations

ATP-dependent Transport of Reduced Glutathione on YCF1, the Yeast Orthologue of Mammalian Multidrug Resistance Associated Proteins

1998 • 72 citations

Frequent coexpression of MRP/GS-X pump and γ-glutamylcysteine synthetase mRNA in drug-resistant cells, untreated tumor cells, and normal mouse tissues

1998 • 56 citations

Hepatobiliary excretion of organic anions in double-mutant rats with a combination of defective canalicular transport and uridine 5′-diphosphate-glucuronyltransferase deficiency

1987 • 44 citations

Overexpression of mdr2 gene by peroxisome proliferations in the mouse liver

1997 • 41 citations

Differences between nuclear run-off and mRNA levels for multidrug resistance gene expression in the cephalocaudal axis of the mouse intestine

1995 • 34 citations

The effect of the herbicide 2,4,5 trichlorophenoxy acetic acid (245T) on the growth and metabolism of Tetrahymena pyriformis

1975 • 10 citations

Metabolism and distribution of 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) in pregnant mice.

1979 • 4 citations