The effects of lipids and detergents on ATPase-active P-glycoprotein

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

1989 • 7,327 citations

Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies

1985 • 927 citations

Regulation of membrane enzymes by lipids

1978 • 906 citations

Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase.

1992 • 629 citations

P‐glycoprotein: multidrug‐resistance and a superfamily of membrane‐associated transport proteins

1989 • 512 citations

A method for the determination of inorganic phosphate in the presence of labile organic phosphate and high concentrations of protein: Application to lens ATPases

1988 • 480 citations

Phospholipid requirements for (Na+ + K+)-ATPase activity: Head-group specificity and fatty acid fluidity

1972 • 359 citations

Purification of the 170- to 180-kilodalton membrane glycoprotein associated with multidrug resistance. 170- to 180-kilodalton membrane glycoprotein is an ATPase.

1988 • 340 citations

The function of Gp170, the multidrug resistance gene product, in rat liver canalicular membrane vesicles

1989 • 329 citations

Binding protein-dependent transport systems

1990 • 272 citations

Bacterial periplasmic permeases belong to a family of transport proteins operating from to human: Traffic ATPases

1990 • 230 citations

Multidrug Resistance

1991 • 207 citations

Investigation of the essential boundary layer phospholipids of cytochrome c oxidase using Triton X-100 delipidation

1980 • 194 citations

Characterization of the ATPase activity of the Mr 170,000 to 180,000 membrane glycoprotein (P-glycoprotein) associated with multidrug resistance in K562/ADM cells.

1988 • 176 citations

Competitive interaction of cyclosporins with the Vinca alkaloid-binding site of P-glycoprotein in multidrug-resistant cells.

1990 • 167 citations

ATPase activity of partially purified P-glycoprotein from multidrug-resistant Chinese hamster ovary cells

1992 • 147 citations

Interactions between components in biological membranes and their implications for membrane function

1984 • 141 citations

Functional reconstitution of the sodium pump. Kinetics of exchange reactions performed by reconstituted Na/K-ATPase

1991 • 126 citations

Genetic basis of multidrug resistance of tumor cells

1990 • 124 citations

The membrane-bound proteins of periplasmic permeases form a complex. Identification of the histidine permease HisQMP complex

1991 • 119 citations

Transport properties of P-glycoprotein in plasma membrane vesicles from multidrug-resistant Chinese hamster ovary cells

1992 • 114 citations

Interaction of D-beta-hydroxybutyrate apodehydrogenase with phospholipids.

1975 • 113 citations

Current ideas on the significance of protein glycosylation

1986 • 108 citations

Properties of the Neurospora crassa plasma membrane ATPase

1977 • 102 citations

Lipid specificity of beta-hydroxybutyrate dehydrogenase activation.

1975 • 91 citations

Agents which reverse multidrug-resistance are inhibitors of [3H]vinblastine transport by isolated vesicles

1991 • 85 citations

Simultaneous expression of two P-glycoprotein genes in drug-sensitive Chinese hamster ovary cells.

1987 • 84 citations

Phospholipid-protein interactions in the Ca2+-adenosine triphosphatase of sarcoplasmic reticulum.

1976 • 81 citations

The role of N-linked oligosaccharides in glycoprotein function

1991 • 73 citations

P-glycoprotein. ATP hydrolysis by the N-terminal nucleotide-binding domain.

1992 • 69 citations

Lipid requirements of the plasma membrane ATPases from oat roots and yeast

1988 • 66 citations

The role of phospholipid acyl chains in the activation of mitochondrial ATPase complex

1975 • 66 citations

Phospholipid reactivation of the purified plasma membrane ATPase of yeast.

1980 • 61 citations

The phospholipid headgroup specificity of an atp-dependent calcium pump

1978 • 51 citations

Membrane translocation of proteins without hydrophobic signal peptides

1990 • 48 citations

Strategies for the purification of P-glycoprotein from multidrug-resistant Chinese hamster ovary cells

1991 • 38 citations

Uptake at Ca2+ mediated by the (Ca2+ + Mg2+)-ATPase in reconstituted vesicles

1987 • 32 citations