Suppressor gene alterations in the colorectal adenoma-carcinoma sequence

A genetic model for colorectal tumorigenesis

1990 • 11,800 citations

p53 Mutations in Human Cancers

1991 • 8,133 citations

Genetic Alterations during Colorectal-Tumor Development

1988 • 6,691 citations

Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms

1990 • 3,720 citations

Mutations in the p53 gene occur in diverse human tumour types

1989 • 2,765 citations

Identification of FAP Locus Genes from Chromosome 5q21

1991 • 2,358 citations

Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas

1989 • 2,081 citations

Mutations of Chromosome 5q21 Genes in FAP and Colorectal Cancer Patients

1991 • 1,890 citations

Identification of a Chromosome 18q Gene that Is Altered in Colorectal Cancers

1990 • 1,747 citations

Localization of the gene for familial adenomatous polyposis on chromosome 5

1987 • 1,386 citations

Allelotype of Colorectal Carcinomas

1989 • 1,333 citations

Hereditary cancer, oncogenes, and antioncogenes.

1985 • 1,261 citations

Identification of deletion mutations and three new genes at the familial polyposis locus

1991 • 769 citations

Identification of a Gene Located at Chromosome 5q21 that Is Mutated in Colorectal Cancers

1991 • 758 citations

The Gene for Familial Polyposis Coli Maps to the Long Arm of Chromosome 5

1987 • 683 citations

Chromosome 5 allele loss in human colorectal carcinomas

1987 • 566 citations

Distinct sequence elements control the specificity of G protein activation by muscarinic acetylcholine receptor subtypes.

1990 • 192 citations

Suppression of tumorigenicity in human colon carcinoma cells by introduction of normal chromosome 5 or 18

1991 • 184 citations

Hereditary nonpolyposis colorectal cancer (lynch syndromes I and II). II. Biomarker studies

1985 • 165 citations

Regional mapping panel for human chromosome 17: Application to neurofibromatosis type 1

1987 • 120 citations

Evidence supporting exclusion of the DCC gene and a portion of chromosome 18q as the locus for susceptibility to hereditary nonpolyposis colorectal carcinoma in five kindreds.

1991 • 43 citations

Twelve loci form a continuous linkage map for human chromosome 18

1988 • 32 citations