Evidence supporting exclusion of the DCC gene and a portion of chromosome 18q as the locus for susceptibility to hereditary nonpolyposis colorectal carcinoma in five kindreds.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Mutation and Cancer: Statistical Study of Retinoblastoma

1971 • 7,335 citations

Genetic Alterations during Colorectal-Tumor Development

1988 • 6,691 citations

Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms

1990 • 3,720 citations

Strategies for multilocus linkage analysis in humans.

1984 • 2,600 citations

Identification of a Chromosome 18q Gene that Is Altered in Colorectal Cancers

1990 • 1,747 citations

Localization of the gene for familial adenomatous polyposis on chromosome 5

1987 • 1,386 citations

Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants.

1977 • 1,372 citations

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li–Fraumeni syndrome

1990 • 1,228 citations

A genetic linkage map of the human genome

1987 • 913 citations

The Gene for Familial Polyposis Coli Maps to the Long Arm of Chromosome 5

1987 • 683 citations

Re-evaluation of the linkage relationship between chromosome 11p loci and the gene for bipolar affective disorder in the Old Order Amish

1989 • 443 citations

Hereditary nonpolyposis colorectal cancer (lynch syndromes I and II). I. Clinical description of resource

1985 • 402 citations

Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder

1990 • 396 citations

Use of cyclosporin a in establishing epstein-barr virus-transformed human lymphoblastoid cell lines

1984 • 355 citations

MULTIPLE GENETIC ALTERATIONS IN DISTAL AND PROXIMAL COLORECTAL CANCER

1989 • 306 citations

Frequency of hereditary colorectal carcinoma

1987 • 271 citations

Genetic Analysis of an Inherited Predisposition to Colon Cancer in a Family with a Variable Number of Adenomatous Polyps

1990 • 254 citations

Clinical features of colorectal carcinoma in cancer family syndrome

1986 • 206 citations

Tumor spectrum in cancer family syndrome (hereditary nonpolyposis colorectal cancer)

1991 • 199 citations

The tumour spectrum in hereditary non‐polyposis colorectal cancer: A study of 24 kindreds in the netherlands

1990 • 190 citations

Suppression of tumorigenicity in human colon carcinoma cells by introduction of normal chromosome 5 or 18

1991 • 184 citations

Hereditary nonpolyposis colorectal cancer (lynch syndromes I and II). II. Biomarker studies

1985 • 165 citations

DNA rearrangements in human follicular lymphoma can involve the 5' or the 3' region of the bcl-2 gene.

1987 • 151 citations

Natural history of colorectal cancer in hereditary nonpolyposis colorectal cancer (Lynch syndromes I and II)

1988 • 137 citations

Cancer family syndrome. Genetic analysis of 22 Finnish kindreds.

1986 • 119 citations

Heredity and Adenocarcinoma of the Colon

1967 • 108 citations

Inheritance of Proliferative Breast Disease in Breast Cancer Kindreds

1990 • 106 citations

Report of the nomenclature committee and the 1989 catalog of mapped genes (Part 1 of 3)

1989 • 63 citations

Phenotypic variation in colorectal adenoma/cancer expression in two families. Hereditary flat adenoma syndrome

1990 • 59 citations

Frequency of hereditary nonpolyposis colorectal carcinoma (Lynch syndromes I and II)

1986 • 57 citations

Cancer family syndrome

1986 • 57 citations

The Kidd (JK) blood group locus assigned to chromosome 18 by close linkage to a DNA-RFLP

1987 • 54 citations

Twelve loci form a continuous linkage map for human chromosome 18

1988 • 32 citations