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2006 • 6,720 citations

The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

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Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

2005 • 4,573 citations

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1996 • 4,512 citations

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

2005 • 4,165 citations

Toll-like receptor control of the adaptive immune responses

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IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

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1992 • 3,751 citations

TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

2006 • 3,545 citations

A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment

2000 • 3,456 citations

Approaching the Asymptote? Evolution and Revolution in Immunology

1989 • 3,079 citations

Transforming growth factor-β induces development of the TH17 lineage

2006 • 3,014 citations

Interleukin-23 Promotes a Distinct CD4 T Cell Activation State Characterized by the Production of Interleukin-17

2003 • 1,828 citations

A function for interleukin 2 in Foxp3-expressing regulatory T cells

2005 • 1,744 citations

IgG Fc Receptors

2001 • 1,667 citations

Requirement of Interleukin 17 Receptor Signaling for Lung Cxc Chemokine and Granulocyte Colony-Stimulating Factor Expression, Neutrophil Recruitment, and Host Defense

2001 • 1,505 citations

Th17: An Effector CD4 T Cell Lineage with Regulatory T Cell Ties

2006 • 1,403 citations

Cooperation of Toll-like receptor signals in innate immune defence

2007 • 1,320 citations

Dectin-1 is required for β-glucan recognition and control of fungal infection

2006 • 1,105 citations

Regulation of the Interleukin (IL)-12R β2 Subunit Expression in Developing T Helper 1 (Th1) and Th2 Cells

1997 • 1,022 citations

Molecular Mechanisms RegulatinG Th1 Immune Responses

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Syk-Dependent Cytokine Induction by Dectin-1 Reveals a Novel Pattern Recognition Pathway for C Type Lectins

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Regulation of Immunity to Parasites by T Cells and T Cell-Derived Cytokines

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Requirement of Interleukin‐17A for Systemic Anti–Candida albicansHost Defense in Mice

2004 • 840 citations

Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity

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Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans

2006 • 600 citations

Expanding the effector CD4 T-cell repertoire: the Th17 lineage

2006 • 595 citations

The TREM receptor family and signal integration

2006 • 531 citations

Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance

2006 • 525 citations

Myeloid C-type lectins in innate immunity

2006 • 505 citations

Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production

2005 • 501 citations

Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling

2005 • 473 citations

T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis

2007 • 469 citations

A role for fungal β-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice

2005 • 423 citations

The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens

2006 • 403 citations

Signals mediated by transforming growth factor-β initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease

2006 • 392 citations

Transferring functional immune responses to pathogens after haploidentical hematopoietic transplantation

2005 • 377 citations

Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs

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2003 • 353 citations

One-Step Purification of Recombinant Proteins Using a Nanomolar-Affinity Streptavidin-Binding Peptide, the SBP-Tag

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Cytokine production by mouse myeloid dendritic cells in relation to differentiation and terminal maturation induced by lipopolysaccharide or CD40 ligation

2001 • 230 citations

A Protective and Agonistic Function of IL-12p40 in Mycobacterial Infection

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T Cell Vaccination in Mice with Invasive Pulmonary Aspergillosis

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Th1 and Th2 cytokines in mice with invasive aspergillosis

1997 • 216 citations

Immunity to fungi

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Innate Immune Activation and CD4+ T Cell Priming during Respiratory Fungal Infection

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TGF-beta is important in determining the in vivo patterns of susceptibility or resistance in mice infected with Candida albicans.

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T Cells Induce Extended Class II MHC Compartments in Dendritic Cells in a Toll-Like Receptor-Dependent Manner

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Immunity to fungi

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Innate and adaptive determinants of host susceptibility to medically important fungi

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Distinct contributions of different CD40 TRAF binding sites to CD154‐induced dendritic cell maturation and IL‐12 secretion

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β‐Glucan Derived from Zymosan Acts as an Adjuvant for Collagen‐Induced Arthritis

2006 • 22 citations